Haoyu Chao,Shilong Zhang,Yueming Hu et al.
Haoyu Chao et al.
Crop plant breeding involves selecting and developing new plant varieties with desirable traits such as increased yield, improved disease resistance, and enhanced nutritional value. With the development of high-throughput technologies, such...
Artificial Bee Colony algorithm in estimating kinetic parameters for yeast fermentation pathway [0.03%]
人工蜂群算法在酵母发酵途径中估计动力学参数方面的应用
Ahmad Muhaimin Ismail,Muhammad Akmal Remli,Yee Wen Choon et al.
Ahmad Muhaimin Ismail et al.
Analyzing metabolic pathways in systems biology requires accurate kinetic parameters that represent the simulated in vivo processes. Simulation of the fermentation pathway in the Saccharomyces cerevisiae kinetic model help saves much time i...
Specifications of standards in systems and synthetic biology: status and developments in 2022 and the COMBINE meeting 2022 [0.03%]
系统与合成生物学中的标准规范：2022年标准规范工作组的现状与发展及COMBINE会议2022
Matthias König,Padraig Gleeson,Martin Golebiewski et al.
Matthias König et al.
This special issue of the Journal of Integrative Bioinformatics contains updated specifications of COMBINE standards in systems and synthetic biology. The 2022 special issue presents three updates to the standards: CellML 2.0.1, SBML Level ...
Study of NAD-interacting proteins highlights the extent of NAD regulatory roles in the cell and its potential as a therapeutic target [0.03%]
NAD互作蛋白的研究揭示了NAD在细胞中的调控作用及其作为治疗靶点的潜力
Sara Duarte-Pereira,Sérgio Matos,José Luís Oliveira et al.
Sara Duarte-Pereira et al.
Nicotinamide adenine dinucleotide (NAD) levels are essential for the normal physiology of the cell and are strictly regulated to prevent pathological conditions. NAD functions as a coenzyme in redox reactions, as a substrate of regulatory p...
Application of machine learning approach in emergency department to support clinical decision making for SARS-CoV-2 infected patients [0.03%]
机器学习在急诊科的应用可助力临床决策支持新型冠状病毒肺炎患者的诊疗
Nicolò Casano,Silvano Junior Santini,Pierpaolo Vittorini et al.
Nicolò Casano et al.
To support physicians in clinical decision process on patients affected by Coronavirus Disease 2019 (COVID-19) in areas with a low vaccination rate, we devised and evaluated the performances of several machine learning (ML) classifiers fed ...
Observational Study
Journal of integrative bioinformatics. 2023 Mar 7;20(2):20220047. DOI:10.1515/jib-2022-0047 2023
On the identification of potential novel therapeutic targets for spinocerebellar ataxia type 1 (SCA1) neurodegenerative disease using EvoPPI3 [0.03%]
基于EvoPPI3的脊髓小脑共济失调1型潜在药物靶点预测研究
André Sousa,Sara Rocha,Jorge Vieira et al.
André Sousa et al.
EvoPPI (http://evoppi.i3s.up.pt), a meta-database for protein-protein interactions (PPI), has been upgraded (EvoPPI3) to accept new types of data, namely, PPI from patients, cell lines, and animal models, as well as data from gene modifier ...
Community-wide collaboration is a must to reinstall trust in bioinformatics solutions and biomedical interpretation [0.03%]
重建人们对生物信息解决方案及生物医学解释信任须举社区之力
Savaş Takan,Jens Allmer
Savaş Takan
Science has become a highly competitive undertaking concerning, for example, resources, positions, students, and publications. At the same time, the number of journals presenting scientific findings skyrockets while the knowledge increase p...
Diabetes disease prediction system using HNB classifier based on discretization method [0.03%]
基于离散化方法的HNB分类器的糖尿病疾病预测系统
Bassam Abdo Al-Hameli,AbdulRahman A Alsewari,Shadi S Basurra et al.
Bassam Abdo Al-Hameli et al.
Diagnosing diabetes early is critical as it helps patients live with the disease in a healthy way - through healthy eating, taking appropriate medical doses, and making patients more vigilant in their movements/activities to avoid wounds th...
Irina Balaur,Ludovic Roy,Vasundra Touré et al.
Irina Balaur et al.
Systems biology researchers need feasible solutions for editing and visualisation of large biological diagrams. Here, we present the ySBGN bidirectional converter that translates metabolic pathways, developed in the general-purpose yEd Grap...
Towards a hybrid user interface for the visual exploration of large biomolecular networks using virtual reality [0.03%]
基于虚拟现实的大分子生物网络可视化探索混合用户界面的研究
Michael Aichem,Karsten Klein,Tobias Czauderna et al.
Michael Aichem et al.
Biomolecular networks, including genome-scale metabolic models (GSMMs), assemble the knowledge regarding the biological processes that happen inside specific organisms in a way that allows for analysis, simulation, and exploration. With the...