Application of machine learning approach in emergency department to support clinical decision making for SARS-CoV-2 infected patients [0.03%]
机器学习在急诊科的应用可助力临床决策支持新型冠状病毒肺炎患者的诊疗
Nicolò Casano,Silvano Junior Santini,Pierpaolo Vittorini et al.
Nicolò Casano et al.
To support physicians in clinical decision process on patients affected by Coronavirus Disease 2019 (COVID-19) in areas with a low vaccination rate, we devised and evaluated the performances of several machine learning (ML) classifiers fed ...
Observational Study
Journal of integrative bioinformatics. 2023 Mar 7;20(2):20220047. DOI:10.1515/jib-2022-0047 2023
On the identification of potential novel therapeutic targets for spinocerebellar ataxia type 1 (SCA1) neurodegenerative disease using EvoPPI3 [0.03%]
基于EvoPPI3的脊髓小脑共济失调1型潜在药物靶点预测研究
André Sousa,Sara Rocha,Jorge Vieira et al.
André Sousa et al.
EvoPPI (http://evoppi.i3s.up.pt), a meta-database for protein-protein interactions (PPI), has been upgraded (EvoPPI3) to accept new types of data, namely, PPI from patients, cell lines, and animal models, as well as data from gene modifier ...
Community-wide collaboration is a must to reinstall trust in bioinformatics solutions and biomedical interpretation [0.03%]
重建人们对生物信息解决方案及生物医学解释信任须举社区之力
Savaş Takan,Jens Allmer
Savaş Takan
Science has become a highly competitive undertaking concerning, for example, resources, positions, students, and publications. At the same time, the number of journals presenting scientific findings skyrockets while the knowledge increase p...
Diabetes disease prediction system using HNB classifier based on discretization method [0.03%]
基于离散化方法的HNB分类器的糖尿病疾病预测系统
Bassam Abdo Al-Hameli,AbdulRahman A Alsewari,Shadi S Basurra et al.
Bassam Abdo Al-Hameli et al.
Diagnosing diabetes early is critical as it helps patients live with the disease in a healthy way - through healthy eating, taking appropriate medical doses, and making patients more vigilant in their movements/activities to avoid wounds th...
Irina Balaur,Ludovic Roy,Vasundra Touré et al.
Irina Balaur et al.
Systems biology researchers need feasible solutions for editing and visualisation of large biological diagrams. Here, we present the ySBGN bidirectional converter that translates metabolic pathways, developed in the general-purpose yEd Grap...
Towards a hybrid user interface for the visual exploration of large biomolecular networks using virtual reality [0.03%]
基于虚拟现实的大分子生物网络可视化探索混合用户界面的研究
Michael Aichem,Karsten Klein,Tobias Czauderna et al.
Michael Aichem et al.
Biomolecular networks, including genome-scale metabolic models (GSMMs), assemble the knowledge regarding the biological processes that happen inside specific organisms in a way that allows for analysis, simulation, and exploration. With the...
Co-creation environment with cloud virtual reality and real-time artificial intelligence toward the design of molecular robots [0.03%]
基于云虚拟现实和实时人工智能的分子机器人设计共创新环境
Akihiko Konagaya,Gregory Gutmann,Yuhui Zhang
Akihiko Konagaya
This paper describes the design philosophy for our cloud-based virtual reality (VR) co-creation environment (CCE) for molecular modeling. Using interactive VR simulation can provide enhanced perspectives in molecular modeling for intuitive ...
In silico studies of natural product-like caffeine derivatives as potential MAO-B inhibitors/AA2AR antagonists for the treatment of Parkinson's disease [0.03%]
计算研究咖啡因类似物作为治疗帕金森病的单胺氧化酶B抑制剂/5-HT2A受体拮抗剂的潜力
Yassir Boulaamane,Mahmoud A A Ibrahim,Mohammed Reda Britel et al.
Yassir Boulaamane et al.
Parkinson's disease is considered the second most frequent neurodegenerative disease. It is described by the loss of dopaminergic neurons in the mid-brain. For many decades, L-DOPA has been considered as the gold standard for treating Parki...
Bridging data management platforms and visualization tools to enable ad-hoc and smart analytics in life sciences [0.03%]
打通数据管理平台与可视化工具，实现生命科学领域的即席和智能分析
Christian Panse,Christian Trachsel,Can Türker
Christian Panse
Core facilities have to offer technologies that best serve the needs of their users and provide them a competitive advantage in research. They have to set up and maintain instruments in the range of ten to a hundred, which produce large amo...
Manuel Feser,Patrick König,Anne Fiebig et al.
Manuel Feser et al.
Over the last years it has been observed that the progress in data collection in life science has created increasing demand and opportunities for advanced bioinformatics. This includes data management as well as the individual data analysis...