PharmoCo: a graph-based visualization of pharmacogenomic plausibility check reports for clinical decision support systems [0.03%]
PharmoCo: 用于临床决策支持系统的药理基因组学合理检查报告的基于图形的可视化工具
Lena Raupach,Cassandra Königs
Lena Raupach
The first approaches in recent years for the integration of pharmacogenomic plausibility checks into clinical practice show both a promising improvement in the drug therapy safety, but also difficulties in application. One of the difficulti...
Gene-network based analysis of human placental trophoblast subtypes identifies critical genes as potential targets of therapeutic drugs [0.03%]
基于基因网络分析人类胎盘滋养外胚层亚型鉴别关键的基因为治疗药物的潜在靶点
Andreas Ian Lackner,Jürgen Pollheimer,Paulina Latos et al.
Andreas Ian Lackner et al.
During early pregnancy, extravillous trophoblasts (EVTs) play a crucial role in modifying the maternal uterine environment. Failures in EVT lineage formation and differentiation can lead to pregnancy complications such as preeclampsia, feta...
An overview of machine learning and deep learning techniques for predicting epileptic seizures [0.03%]
癫痫发作预测中机器学习和深度学习技术的概述
Marco Zurdo-Tabernero,Ángel Canal-Alonso,Fernando de la Prieta et al.
Marco Zurdo-Tabernero et al.
Epilepsy is a neurological disorder (the third most common, following stroke and migraines). A key aspect of its diagnosis is the presence of seizures that occur without a known cause and the potential for new seizures to occur. Machine lea...
SAMNA: accurate alignment of multiple biological networks based on simulated annealing [0.03%]
基于模拟退火的多生物网络精确对齐算法(SAMNA)
Jing Chen,Zixiang Wang,Jia Huang
Jing Chen
Proteins are important parts of the biological structures and encode a lot of biological information. Protein-protein interaction network alignment is a model for analyzing proteins that helps discover conserved functions between organisms ...
Application of Artificial Intelligence or machine learning in risk sharing agreements for pharmacotherapy risk management [0.03%]
人工智能或机器学习在药疗法风险管理中的分担风险协议中的应用
Grigory A Oborotov,Konstantin A Koshechkin,Yuriy L Orlov
Grigory A Oborotov
Applications of Artificial Intelligence in medical informatics solutions risk sharing have social value. At a time of ever-increasing cost for the provision of medicines to citizens, there is a need to restrain the growth of health care cos...
TidyGEO: preparing analysis-ready datasets from Gene Expression Omnibus [0.03%]
TidyGEO：从基因表达概况库准备分析型数据集
Avery Mecham,Ashlie Stephenson,Badi I Quinteros et al.
Avery Mecham et al.
TidyGEO is a Web-based tool for downloading, tidying, and reformatting data series from Gene Expression Omnibus (GEO). As a freely accessible repository with data from over 6 million biological samples across more than 4000 organisms, GEO p...
Katharina Wolff,Ronja Friedhoff,Friderieke Schwarzer et al.
Katharina Wolff et al.
With an ever increasing amount of research data available, it becomes constantly more important to possess data literacy skills to benefit from this valuable resource. An integrative course was developed to teach students the fundamentals o...
Accurate noise-robust classification of Bacillus species from MALDI-TOF MS spectra using a denoising autoencoder [0.03%]
基于MALDI-TOF质谱的芽孢杆菌种类噪声鲁棒分类及其去噪自动编码器实现
Yulia E Uvarova,Pavel S Demenkov,Irina N Kuzmicheva et al.
Yulia E Uvarova et al.
Bacillus strains are ubiquitous in the environment and are widely used in the microbiological industry as valuable enzyme sources, as well as in agriculture to stimulate plant growth. The Bacillus genus comprises several closely related gro...
Reconstruction of the regulatory hypermethylation network controlling hepatocellular carcinoma development during hepatitis C viral infection [0.03%]
丙型肝炎病毒感染过程中调控肝癌发生发展的表观遗传网络重塑
Evgeniya A Antropova,Tamara M Khlebodarova,Pavel S Demenkov et al.
Evgeniya A Antropova et al.
Hepatocellular carcinoma (HCC) has been associated with hepatitis C viral (HCV) infection as a potential risk factor. Nonetheless, the precise genetic regulatory mechanisms triggered by the virus, leading to virus-induced hepatocarcinogenes...
Yuriy L Orlov,Ming Chen,Nikolay A Kolchanov et al.
Yuriy L Orlov et al.