Unlocking the power of AI models: exploring protein folding prediction through comparative analysis [0.03%]
解锁AI模型的力量：通过比较分析探索蛋白质折叠预测
Paloma Tejera-Nevado,Emilio Serrano,Ana González-Herrero et al.
Paloma Tejera-Nevado et al.
Protein structure determination has made progress with the aid of deep learning models, enabling the prediction of protein folding from protein sequences. However, obtaining accurate predictions becomes essential in certain cases where the ...
The simulation experiment description markup language (SED-ML): language specification for level 1 version 5 [0.03%]
模拟实验描述标记语言（SED-ML）：第1版第5次修订的规范说明
Lucian P Smith,Frank T Bergmann,Alan Garny et al.
Lucian P Smith et al.
Modern biological research is increasingly informed by computational simulation experiments, which necessitate the development of methods for annotating, archiving, sharing, and reproducing the conducted experiments. These simulations incre...
Auto-phylo v2 and auto-phylo-pipeliner: building advanced, flexible, and reusable pipelines for phylogenetic inferences, estimation of variability levels and identification of positively selected amino acid sites [0.03%]
Auto-phylo v2和auto-phylo-pipeliner：构建高级、灵活且可重用的管道进行系统发育推断、变异水平估计以及识别正向选择氨基酸位点
Hugo López-Fernández,Miguel Pinto,Cristina P Vieira et al.
Hugo López-Fernández et al.
The vast amount of genome sequence data that is available, and that is predicted to drastically increase in the near future, can only be efficiently dealt with by building automated pipelines. Indeed, the Earth Biogenome Project will produc...
MetaLo: metabolic analysis of Logical models extracted from molecular interaction maps [0.03%]
MetaLo：从分子相互作用图中提取的逻辑模型的代谢分析
Sahar Aghakhani,Anna Niarakis,Sylvain Soliman
Sahar Aghakhani
Molecular interaction maps (MIMs) are static graphical representations depicting complex biochemical networks that can be formalized using one of the Systems Biology Graphical Notation languages. Regardless of their extensive coverage of va...
PharmoCo: a graph-based visualization of pharmacogenomic plausibility check reports for clinical decision support systems [0.03%]
PharmoCo: 用于临床决策支持系统的药理基因组学合理检查报告的基于图形的可视化工具
Lena Raupach,Cassandra Königs
Lena Raupach
The first approaches in recent years for the integration of pharmacogenomic plausibility checks into clinical practice show both a promising improvement in the drug therapy safety, but also difficulties in application. One of the difficulti...
Gene-network based analysis of human placental trophoblast subtypes identifies critical genes as potential targets of therapeutic drugs [0.03%]
基于基因网络分析人类胎盘滋养外胚层亚型鉴别关键的基因为治疗药物的潜在靶点
Andreas Ian Lackner,Jürgen Pollheimer,Paulina Latos et al.
Andreas Ian Lackner et al.
During early pregnancy, extravillous trophoblasts (EVTs) play a crucial role in modifying the maternal uterine environment. Failures in EVT lineage formation and differentiation can lead to pregnancy complications such as preeclampsia, feta...
An overview of machine learning and deep learning techniques for predicting epileptic seizures [0.03%]
癫痫发作预测中机器学习和深度学习技术的概述
Marco Zurdo-Tabernero,Ángel Canal-Alonso,Fernando de la Prieta et al.
Marco Zurdo-Tabernero et al.
Epilepsy is a neurological disorder (the third most common, following stroke and migraines). A key aspect of its diagnosis is the presence of seizures that occur without a known cause and the potential for new seizures to occur. Machine lea...
SAMNA: accurate alignment of multiple biological networks based on simulated annealing [0.03%]
基于模拟退火的多生物网络精确对齐算法(SAMNA)
Jing Chen,Zixiang Wang,Jia Huang
Jing Chen
Proteins are important parts of the biological structures and encode a lot of biological information. Protein-protein interaction network alignment is a model for analyzing proteins that helps discover conserved functions between organisms ...
Application of Artificial Intelligence or machine learning in risk sharing agreements for pharmacotherapy risk management [0.03%]
人工智能或机器学习在药疗法风险管理中的分担风险协议中的应用
Grigory A Oborotov,Konstantin A Koshechkin,Yuriy L Orlov
Grigory A Oborotov
Applications of Artificial Intelligence in medical informatics solutions risk sharing have social value. At a time of ever-increasing cost for the provision of medicines to citizens, there is a need to restrain the growth of health care cos...
TidyGEO: preparing analysis-ready datasets from Gene Expression Omnibus [0.03%]
TidyGEO：从基因表达概况库准备分析型数据集
Avery Mecham,Ashlie Stephenson,Badi I Quinteros et al.
Avery Mecham et al.
TidyGEO is a Web-based tool for downloading, tidying, and reformatting data series from Gene Expression Omnibus (GEO). As a freely accessible repository with data from over 6 million biological samples across more than 4000 organisms, GEO p...