Fast alignment of reads to a variation graph with application to SNP detection [0.03%]
快速将读取与变异图对齐在SNP检测中的应用
Maurilio Monsu,Matteo Comin
Maurilio Monsu
Sequencing technologies has provided the basis of most modern genome sequencing studies due to its high base-level accuracy and relatively low cost. One of the most demanding step is mapping reads to the human reference genome. The reliance...
Glioblastoma gene network reconstruction and ontology analysis by online bioinformatics tools [0.03%]
通过在线生物信息学工具重建胶质母细胞瘤基因网络和本体论分析
Natalya V Gubanova,Nina G Orlova,Arthur I Dergilev et al.
Natalya V Gubanova et al.
Glioblastoma is the most aggressive type of brain tumors resistant to a number of antitumor drugs. The problem of therapy and drug treatment course is complicated by extremely high heterogeneity in the benign cell populations, the random ar...
An evaluation study of biclusters visualization techniques of gene expression data [0.03%]
基因表达数据双聚类可视化技术的评估研究
Haithem Aouabed,Mourad Elloumi,Rodrigo Santamaría
Haithem Aouabed
Biclustering is a non-supervised data mining technique used to analyze gene expression data, it consists to classify subgroups of genes that have similar behavior under subgroups of conditions. The classified genes can have independent beha...
Specifications of standards in systems and synthetic biology: status and developments in 2021 [0.03%]
系统与合成生物学标准规范：2021年的状况与发展
Falk Schreiber,Padraig Gleeson,Martin Golebiewski et al.
Falk Schreiber et al.
This special issue of the Journal of Integrative Bioinformatics contains updated specifications of COMBINE standards in systems and synthetic biology. The 2021 special issue presents four updates of standards: Synthetic Biology Open Languag...
Hasan Baig,Pedro Fontanarossa,James McLaughlin et al.
Hasan Baig et al.
People who engineer biological organisms often find it useful to draw diagrams in order to communicate both the structure of the nucleic acid sequences that they are engineering and the functional relationships between sequence features and...
John H Gennari,Matthias König,Goksel Misirli et al.
John H Gennari et al.
A standardized approach to annotating computational biomedical models and their associated files can facilitate model reuse and reproducibility among research groups, enhance search and retrieval of models and data, and enable semantic comp...
Big data in the healthcare system: a synergy with artificial intelligence and blockchain technology [0.03%]
医疗保健系统中的大数据：与人工智能及区块链技术的结合力
Reyes-González Juan Pablo,Díaz-Peregrino Roberto,Soto-Ulloa Victor et al.
Reyes-González Juan Pablo et al.
In the last decades big data has facilitating and improving our daily duties in the medical research and clinical fields; the strategy to get to this point is understanding how to organize and analyze the data in order to accomplish the fin...
Aneesh Kotipalli,Ravikumar Gutti,Chanchal K Mitra
Aneesh Kotipalli
MicroRNAs (miRNAs) are short noncoding RNA sequences ~22 nucleotides in length that play an important role in gene regulation-transcription and translation. The processing of these miRNAs takes place in both the nucleus and the cytoplasm wh...
In silico gene knockout prediction using a hybrid of Bat algorithm and minimization of metabolic adjustment [0.03%]
基于蝙蝠算法和代谢调整最小化的基因敲除预测（英文）
Mei Yen Man,Mohd Saberi Mohamad,Yee Wen Choon et al.
Mei Yen Man et al.
Microorganisms commonly produce many high-demand industrial products like fuels, food, vitamins, and other chemicals. Microbial strains are the strains of microorganisms, which can be optimized to improve their technological properties thro...
On the border of the amyloidogenic sequences: prefix analysis of the parallel beta sheets in the PDB_Amyloid collection [0.03%]
基于PDB_Amyloid数据库的平行β折叠前体序列分析
Kristóf Takács,Vince Grolmusz
Kristóf Takács
The Protein Data Bank (PDB) today contains more than 174,000 entries with the 3-dimensional structures of biological macromolecules. Using the rich resources of this repository, it is possible identifying subsets with specific, interesting ...