Statistical estimates of multiple transcription factors binding in the model plant genomes based on ChIP-seq data [0.03%]
基于ChIP-seq数据的模式植物基因组中多个转录因子结合位点的统计估计方法研究
Arthur I Dergilev,Nina G Orlova,Oxana B Dobrovolskaya et al.
Arthur I Dergilev et al.
The development of high-throughput genomic sequencing coupled with chromatin immunoprecipitation technologies allows studying the binding sites of the protein transcription factors (TF) in the genome scale. The growth of data volume on the ...
Predicting the possible effect of miR-203a-3p and miR-29a-3p on DNMT3B and GAS7 genes expression [0.03%]
miR-203a-3p和miR-29a-3p可能影响DNMT3B和GAS7基因表达的预测分析研究
Afgar Ali,Sattarzadeh Bardsiri Mahla,Vahidi Reza et al.
Afgar Ali et al.
Aberrant expression of genes involved in methylation, including DNA methyltransferase 3 Beta (DNMT3B), can cause hypermethylation of various tumor suppressor genes. In this regard, various molecular factors such as microRNAs can play a crit...
Special Issue of the 1st International Applied Bioinformatics Conference (iABC'21) [0.03%]
第1届国际应用生物信息学会议(iABC'21)特刊
Jens Allmer,Mourad Elloumi,Matteo Comin et al.
Jens Allmer et al.
Modular network inference between miRNA-mRNA expression profiles using weighted co-expression network analysis [0.03%]
使用加权共表达网络分析在miRNA-mRNA表达谱之间进行模块化网络推断
Nisar Wani,Debmalya Barh,Khalid Raza
Nisar Wani
Connecting transcriptional and post-transcriptional regulatory networks solves an important puzzle in the elucidation of gene regulatory mechanisms. To decipher the complexity of these connections, we build co-expression network modules for...
Disparity-filtered differential correlation network analysis: a case study on CRC metabolomics [0.03%]
差异过滤的差异相关网络分析：一项关于CRC代谢组学的研究案例
Silvia Sabatini,Amalia Gastaldelli
Silvia Sabatini
Differential network analysis has become a widely used technique to investigate changes of interactions among different conditions. Although the relationship between observed interactions and biochemical mechanisms is hard to establish, dif...
In silico approach to understand epigenetics of POTEE in ovarian cancer [0.03%]
利用计算机模拟理解卵巢癌中POTEE的表观遗传学
Sahar Qazi,Khalid Raza
Sahar Qazi
Ovarian cancer is the third leading cause of cancer-related deaths in India. Epigenetics mechanisms seemingly plays an important role in ovarian cancer. This paper highlights the crucial epigenetic changes that occur in POTEE that get hypom...
Fast alignment of reads to a variation graph with application to SNP detection [0.03%]
快速将读取与变异图对齐在SNP检测中的应用
Maurilio Monsu,Matteo Comin
Maurilio Monsu
Sequencing technologies has provided the basis of most modern genome sequencing studies due to its high base-level accuracy and relatively low cost. One of the most demanding step is mapping reads to the human reference genome. The reliance...
Glioblastoma gene network reconstruction and ontology analysis by online bioinformatics tools [0.03%]
通过在线生物信息学工具重建胶质母细胞瘤基因网络和本体论分析
Natalya V Gubanova,Nina G Orlova,Arthur I Dergilev et al.
Natalya V Gubanova et al.
Glioblastoma is the most aggressive type of brain tumors resistant to a number of antitumor drugs. The problem of therapy and drug treatment course is complicated by extremely high heterogeneity in the benign cell populations, the random ar...
An evaluation study of biclusters visualization techniques of gene expression data [0.03%]
基因表达数据双聚类可视化技术的评估研究
Haithem Aouabed,Mourad Elloumi,Rodrigo Santamaría
Haithem Aouabed
Biclustering is a non-supervised data mining technique used to analyze gene expression data, it consists to classify subgroups of genes that have similar behavior under subgroups of conditions. The classified genes can have independent beha...
Specifications of standards in systems and synthetic biology: status and developments in 2021 [0.03%]
系统与合成生物学标准规范：2021年的状况与发展
Falk Schreiber,Padraig Gleeson,Martin Golebiewski et al.
Falk Schreiber et al.
This special issue of the Journal of Integrative Bioinformatics contains updated specifications of COMBINE standards in systems and synthetic biology. The 2021 special issue presents four updates of standards: Synthetic Biology Open Languag...