Polyphenols as Systems Modulators of the Gut-Brain-Liver Axis: A Narrative Review of Neuro-Metabolic and Immunomodulatory Networks [0.03%]
polyphenols对肠-脑-肝轴的系统调节作用：神经代谢和免疫网络叙述性综述
Aftab Alam,Talha Jawaid
Aftab Alam
Dietary polyphenols are gaining attention as regulators of gut-brain-liver (GBL) signaling in metabolic disease. The objective of this narrative review is to examine how polyphenols affect neuro-metabolic and immune pathways across the gut-...
Polyphenols as Systems Modulators of the Gut-Brain-Liver Axis: A Narrative Review of Neuro-Metabolic and Immunomodulatory Networks [0.03%]
polyphenols对肠-脑-肝轴的系统调节作用：神经代谢和免疫调节网络的叙述性综述
Aftab Alam,Talha Jawaid
Aftab Alam
Dietary polyphenols are gaining attention as regulators of gut-brain-liver (GBL) signaling in metabolic disease. The objective of this narrative review is to examine how polyphenols affect neuro-metabolic and immune pathways across the gut-...
Daidzein Mitigates Nicotine-Induced Atherogenesis via Nrf2/ROS/TXNIP-Dependent Inhibition of Macrophage Pyroptosis and Lipid Accumulation [0.03%]
染料小质诱导的核因子E2相关因子2/反应性氧物质/硫氧还蛋白结合蛋白依赖性的巨噬细胞焦亡和脂质积累抑制作用缓解尼古丁促动脉粥样硬化作用
Xiao-Dan Xu,Kun Ren,Xian Liu et al.
Xiao-Dan Xu et al.
Food-derived bioactive components play a crucial role in the prevention of cardiovascular diseases. Daidzein (DAI), a soy isoflavone, possesses notable cardioprotective potential; however, its precise role in nicotine-induced atherosclerosi...
Dietary Fatty Acids Differentially Modulate Hippocampal Glutamate-Related Gene Expression in Mice: Sex-Specific in Vivo and in Vitro Effects [0.03%]
膳食脂肪酸差异调节小鼠海马谷氨酸相关基因表达：性别特异的体内和体外效应
Laura Romero-Muñoz,Beatriz Merino,Enrique Sánchez-Hita et al.
Laura Romero-Muñoz et al.
High-fat diets (HFDs) disrupt hippocampal (HIP) glutamatergic transmission, reducing synaptic plasticity and contributing to cognitive decline. While excessive dietary fat is known to alter glutamate (Glu) homeostasis, the specific effects ...
The Dietary Protein Source Modulates Obesity Development and Induces Distinct Plasma Lipid Profiles and Transcriptome Profiles in Liver and Adipose Tissue [0.03%]
饮食性蛋白质来源可调节肥胖的发生，并诱导肝脏和脂肪组织中的不同的血浆脂质谱和转录组学谱式
Lene S Myrmel,Even Fjære,Annette Bernhard et al.
Lene S Myrmel et al.
Diets based on dairy or seafood proteins are reported to be less obesogenic than diets based on terrestrial meat proteins. The metabolic pathways underlying these differences, including processes related to thermogenesis, remain incompletel...
Phenolic-Rich Lentil Extracts Regulate Cytokine Production, Metabolic Pathways and Barrier Function in Intestinal Epithelial Cells [0.03%]
富含酚的扁豆提取物调节肠道上皮细胞的细胞因子产生、代谢途径和屏障功能
Rafaela Geraldo,Manuela Machado,Eduardo Costa et al.
Rafaela Geraldo et al.
Phenolic compounds are recognized for antioxidant, anti-inflammatory, and antidiabetic properties. Lentils are abundant in these compounds, yet comparative studies across varieties and intestinal cells effects remain limited. This study eva...
Effects of Probiotic Supplementation on Circadian Rhythm-Related Gene Expression and Body Weight in Mice With Disturbed Circadian Rhythms [0.03%]
益生菌对昼夜节律紊乱小鼠的基因表达和体重的影响
Büşra Tepebaşı,Mehtap Ünlü Söğüt,Menşure Nur Çelik et al.
Büşra Tepebaşı et al.
Given the limited knowledge of probiotic effects on clock genes, this study investigated whether probiotics that regulate gut integrity and microbiota balance influence central circadian clock gene expression. In this study conducted on thr...
DASH Diet, Dietary Nitrate, and Nitric Oxide Bioavailability: Implications for Endothelial Dysfunction and Hypertension in Older Adults [0.03%]
针对老年人血管内皮功能障碍和高血压的节氮饮食及膳食硝酸盐与一氧化氮生物利用度的关系研究
Ruhui Zhong,Yuxin Guo,Xinyi You et al.
Ruhui Zhong et al.
Hypertension in the elderly is closely associated with vascular aging, characterized by endothelial dysfunction (ED) and a progressive decline in nitric oxide (NO) bioavailability. Age-related dysfunction of endothelial nitric oxide synthas...
High Methoxyl Pectin Consistently Reduces β-Carotene Bioaccessibility Across Various Gastrointestinal Digestion Conditions [0.03%]
高甲氧基果胶在不同胃肠消化条件下均可降低β-胡萝卜素的生物可及性
Anushka Shukla,Thomas Schleeh,Patrick Borel et al.
Anushka Shukla et al.
Dietary fiber could inhibit β-carotene bioaccessibility by restricting its release from the food matrix, interfering with digestive enzyme activities, binding bile salts, or modifying viscosity and other physicochemical properties of the d...
Heat-Killed Bifidobacterium longum ZFML0012 Alleviates Rheumatoid Arthritis via Gut-Joint Axis Regulation: Remodeling Microbiota, Boosting SCFAs/L-Glutamine, and Rebalancing Th17/Treg Immunity [0.03%]
热灭活长双歧杆菌ZFML0012通过肠道-关节轴调节缓解类风湿性关节炎：重塑微生物群，促进SCFA/L-谷氨酰胺生成并重新平衡Th17/Treg免疫反应
Tiantian Yang,Yubin Zhang,Yingjie Huang et al.
Tiantian Yang et al.
Rheumatoid arthritis (RA) is an autoimmune disease closely associated with gut microbiota dysbiosis. Amid growing interest in microbial-derived therapeutics, postbiotics, defined as preparations of nonliving microorganisms and/or their comp...