From Symbiosis to Cytotoxicity: Biosynthesis, Molecular Mechanisms, and Anticancer Potential of Lichen-Derived Depsides and Depsidones [0.03%]
地衣衍生的二氢衍生物和二氢双烯酮的生物合成、分子机制及抗癌潜力:从共生到细胞毒性
Sachin V Mapari,Subhash B Gaikwad,Ruchira R Sutar et al.
Sachin V Mapari et al.
Lichen is a unique symbiotic organism that consists of fungi and photosynthetic algae and or cyanobacteria. They are known for producing a large repository of secondary metabolites, among which depsides and depsidones gain pharmacological i...
Synthesis, Characterization, In Vitro Anticancer Activity, In Silico ADMET Profiling, and Molecular Docking Studies of Novel 2-Substituted Benzothiazoles: (2-((1S,2S)-2-((E)-substituestyryl)cyclopentyl)benzo[d]thiazoles) [0.03%]
新型2-取代苯并噻唑类化合物的合成、表征、体外抗肿瘤活性及ADMET性质与分子对接研究:(E)-2-((1S,2S)-2-(芳亚乙基)cyclopentyl)benzo[d]thiazoles)
Nuray Üremiş,Muhammed Mehdi Üremiş,Begüm Berna Yerlikaya et al.
Nuray Üremiş et al.
In line with the need for new candidate molecules in cancer treatment, 2-substituted benzothiazole derivatives were synthesized in this study, their antiproliferative activities were evaluated, and their potential was investigated through A...
Integrated Phytochemical and Bioactivity Evaluation of Ocimum tenuiflorum Linn. Essential Oil Against Multidrug-Resistant Aeromonas spp [0.03%]
马拉巴胡椒油树脂对多重耐药爱德华氏菌的植物化学及生物活性评价
Sanghamitra Buragohain,Radhika Rimal,Naisringdi Thaosen et al.
Sanghamitra Buragohain et al.
Plant essential oils extracted from various parts are known for their potential antimicrobial properties. The gas chromatography and mass spectrometry (GC-MS) of Ocimum tenuiflorum essential oil (TEO) revealed estragole and eugenol as major...
Design, Synthesis, and Antifungal Activity of N'-Phenylpicolinohydrazide Derivatives as Potential Antifungal Agents [0.03%]
设计、合成和抗真菌活性的N'-苯基吡啶酰肼衍生物作为潜在的抗真菌剂
Yuhao Zhang,Qi Zhang,Shanshan Yang et al.
Yuhao Zhang et al.
Discovery and development of novel antifungal agents featuring distinctive chemical scaffolds are of paramount importance for sustainable plant protection. In this study, a series of twenty-one N'-phenylpicolinohydrazide derivatives was des...
Chemical Profiling and Biological Activity of Alpinia graminifolia Essential Oils: In Vitro and In Silico Studies [0.03%]
基于Alpinia graminifolia叶和根须精油的化学成分分析及其体外与分子对接研究
Nguyen Hoang Tuan,Le Duc Giang,Hieu Tran-Trung et al.
Nguyen Hoang Tuan et al.
This study aimed to characterize, for the first time, the chemical composition and bioactivities of essential oils (EOs) obtained from different parts of Alpinia graminifolia. Materials and Methods: Fresh samples collected in Bac Giang prov...
Magnoliae flos (Shin-i) Essential Oil and Its Principal Component Eucalyptol Inhibit JAK1 to Counteract the LPS-Induced RAW264.7 Inflammation [0.03%]
木兰花油及其主要成分桉叶素通过抑制JAK1来对抗LPS诱导的RAW264.7炎症反应
Wei Wang,Xiaona Zhang,Penghui Ou et al.
Wei Wang et al.
Magnoliae flos (Shin-i) has been traditionally utilized in Chinese medicine for rhinitis, sinusitis, and headaches. However, the underlying anti-inflammatory mechanisms of Shin-i essential oil (SIEO), especially its effects on the Janus kin...
Antimalarial Bioactive Compounds From Aegle marmelos and Syzygium aromaticum: In Vitro Evaluation and In Silico Molecular Insights [0.03%]
从Aeglemarmelos和Syzygiumaromaticum中获得的抗疟活性化合物:体外评价与计算机分子分析新的见解
Selvam Naveenkumar,Chinnaperumal Kamaraj,Pradisha Prem et al.
Selvam Naveenkumar et al.
Aegle marmelos (Rutaceae) and Syzygium aromaticum (Myrtaceae), have a rich use in Indian traditional medicine with broad-spectrum cures for a range of illnesses. Although crude extract of these plants was found to exhibit antimalarial poten...
Design, Synthesis, and Fungicidal Activity of Isoxazoles/Isoxazolines Containing Dihydrobenzofuran [0.03%]
含二氢苯并呋喃异噁唑/异噁唑啉的合成、设计及杀菌活性研究
Wu Tianle,Liu Shiyu,Zeng Taining et al.
Wu Tianle et al.
In the search for new antifungal agents, a series of isoxazoles (D) and isoxazolines (E) analogs were designed and synthesized. The 2,3-dihydro-2,2-dimethyl-7-benzofuranol was used as the raw material, and the chalcone derivatives were obta...
Phytochemical and Biological Evaluation of Leaves, Stems, and Roots of Schinus weinmanniifolia Mart. Ex Engl [0.03%]
Schinus weinmanniifolia 马特。茎、叶和根的植物化学和生物评价英文摘要英文关键词:Schinus weinmanniifolia;安第斯樱桃;生长抑素;抗氧化剂;抗炎;毒性
João Andrade,Adriana Araújo de Almeida-Apolonio,Fabiana Gomes da Silva Dantas et al.
João Andrade et al.
The genus Schinus L. includes plants used in folk medicine with important pharmacological effects. However, little is known about Schinus weinmanniifolia Mart. ex Engl. This study evaluated the antioxidant, photoprotective, antimicrobial, a...
Emex spinosa (L.) Campd.: A Review on Ethnomedicinal, Phytochemical, Pharmacological, and Toxicological Profile [0.03%]
刺黄耆的药用、植物化学、药理和毒理学特征综述
Smail Amtaghri,Kolawole Olofinsan,Mitchel Otieno Okumu et al.
Smail Amtaghri et al.
Emex spinosa (L.) Campd. (E. spinosa) is a plant species belonging to the Polygonaceae family. It is native to the Middle East, North Africa, and Europe and is most commonly seen on the coastlines of Mediterranean countries. Additionally, i...