Immunophenotypes of Systemic Lupus Erythematosus-Features of Clinical and Laboratory Disorders [0.03%]
系统性红斑狼疮的免疫表型及其临床和实验特征
A S Avdeeva,A P Aleksankin,E V Chetina et al.
A S Avdeeva et al.
Objective: to evaluate subpopulations of B lymphocytes and features of interferon (IFN) status in patients with systemic lupus erythematosus (SLE), to clarify the relationship of immunological parameters with clinical man...
Intravital Optical Bioimaging of Ovarian Cancer Using a Luminescent Cell Line [0.03%]
采用发光细胞系进行卵巢癌活体光学生物影像学研究
E I Shramova,G M Proshkina,S M Deyev
E I Shramova
Intravital bioimaging based on luminescence is an important method for the development and testing of antitumor drugs on model animals and is an essential part of preclinical studies. Bioimaging based on luminescent systems, compared with f...
Comparative Characteristics of Axial Spondyloarthritis and Psoriatic Arthritis with Axial Involvement [0.03%]
轴型强直性脊柱炎与附着点炎型银屑病关节炎的比较特征研究
E E Gubar,T V Korotaeva,T V Dubinina et al.
E E Gubar et al.
of the study was to compare clinical characteristics of patients with axial spondyloarthritis (axSpA)/ankylosing spondylitis (AS) and with axial psoriatic arthritis (axPsA). MATERIALS AND METHODS: . A total of 100 patients were examined: 45...
Assessment of the Damage Index and Its Dynamics in Patients with Non-Systemic Variants of Juvenile Arthritis during the Treatment with Biologics [0.03%]
生物制剂治疗非全身型幼年关节炎患儿疗效及损伤指数评估研究
Z A Kolkhidova,I P Nikishina,S I Glukhova
Z A Kolkhidova
Juvenile idiopathic arthritis (JIA) is characterized by a high risk of joint destruction, extra-articular changes, and rapidly progressive disability. The CHAQ (Childhood Health Assessment Questionnaire) and X-ray are often used to assess f...
Cognitive Impairments in Patients with Rheumatoid Arthritis and Comorbid Anxiety and Depressive Disorders: Outcomes of the Five-Year Prospective Study [0.03%]
类风湿关节炎伴发焦虑和抑郁患者的认知障碍：五年前瞻性研究结果
A A Abramkin,T A Lisitsyna,D Yu Veltishchev et al.
A A Abramkin et al.
The aim of this study was to assess the baseline rates and five-years outcomes of mild cognitive impairments (MCIs) in patients with rheumatoid arthritis (RA) and comorbid anxiety and depressive disorders (ADDs) receiving traditional synthe...
Relation of Cytokine Profile and Antibody Values to Post-Translational Protein Modifications in Patients with Rheumatoid Arthritis (Preliminary Data) [0.03%]
风湿病患者细胞因子谱及抗体值与蛋白翻译后修饰关系的初步研究
D A Dibrov,A S Avdeeva,M E Diatroptov et al.
D A Dibrov et al.
of the study was to investigate the correlation between cytokine levels and values of antibodies to cyclic citrullinated peptide (ACCP) and antibodies to carbamylated proteins (anti-CarP) in patients with rheumatoid arthritis (RA). ...
Intravenous Administration of Heterodimeric Phospholipase A2 HDP-1 Disturbs Cardiovascular System Functions and Biochemical Composition of Blood in Anesthetized Rats [0.03%]
静脉注射异二聚体磷脂酶A2 HDP-1可扰乱麻醉大鼠心血管系统功能及血液生化组成
A M Ismailova,M S Severyukhina,E R Shaykhutdinova et al.
A M Ismailova et al.
Heterodimeric phospholipase A2 HDP-1 from the venom of Nikolsky viper consists of two noncovalently bound subunits-HDP-1P and HDP-1In, the first of which exhibits lipolytic activity, while the second does not. The subunits have similar mole...
Dynamics of Modified Cardiovascular Risk Factors in Patients with Rheumatoid Arthritis on the Background of 5-Year Therapy with an Interleukin 6 Receptor Inhibitor [0.03%]
风湿性关节炎患者接受5年IL-6受体抑制剂治疗的修改心血管危险因素动态监测结果
E V Gerasimova,T V Popkova,I G Kirillova et al.
E V Gerasimova et al.
The effect of an inhibitor of interleukin (IL) 6 receptors on the state of the cardiovascular system in patients with rheumatoid arthritis (RA) remains poorly understood, especially with its long-term use. ...
The Efficacy and Safety of BCD-180, an Anti-TRBV9+ T cell Monoclonal Antibody, in Patients with Active Radiographic Axial Spondyloarthritis: 36-week Results from the Randomized, Double-Blind, Placebo-Controlled Phase 2 Clinical Study ELEFTA [0.03%]
抗TRBV9+T细胞单克隆抗体BCD-180治疗活动性放射学轴向脊柱关节炎患者的疗效和安全性：随机、双盲、安慰剂对照的II期临床研究ELEFTA的52周结果
E L Nasonov,V I Mazurov,A M Lila et al.
E L Nasonov et al.
The study aims to evaluate the clinical efficacy, safety, pharmacokinetics, pharmacodynamics and immunogenicity of seniprutug (BCD-180) in patients with active radiographic axial spondyloarthritis (r-axSpA, or ankylosing spondylitis). ...
T M Reshetnyak,F A Cheldieva,S I Glukhova et al.
T M Reshetnyak et al.
Thrombotic antiphospholipid syndrome (APS) is a condition affecting young people in whom a thromboembolic event occurs in the presence of circulating antiphospholipid antibodies (aPL). ...