Features of Biochemical and Hematological Parameters and Chromosomal Disorders in Lymphocytes of Aging Primates of the Kurchatovsky Complex of Medical Primatology [0.03%]
库恰特夫斯基医学灵长类研究中心衰老猴淋巴细胞生化、血液学参数及染色体异常的特征
O P Chzhu,N S Rudenko,D E Araviaashvili et al.
O P Chzhu et al.
Aging is a key challenge for modern society. In particular, brain aging is accompanied by chronic inflammation, depletion of energy potential, and an increased level of oxidative stress, with changes in blood composition playing a special r...
Pathomorphological Features of Lung Damage Caused by Infection with Various Variants of SARS-CoV-2 in Humanized Model Animals [0.03%]
人源化模式动物感染各种变异株后肺损伤的病理特征分析
A S Chernov,V A Kazakov,I S Gogleva et al.
A S Chernov et al.
The genotypic variability of the SARS-CoV-2 virus is extremely high, and the emergence of new strains raises concerns about their possible high virulence and ability to bypass responses of the body's immune system induced by previous infect...
Expression of Antioxidant Defense Genes Determines Synergistic Ferroptosis Induction by the Combination of Erastin and Omega-3 Docosahexaenoic Acid in Prostate Cancer Cells [0.03%]
泛酸防御基因表达决定尔塞丁和欧米茄-3二十二碳六烯酸联合诱导前列腺癌细胞铁死亡的协同效应
M O Silkina,T A Kulagin,K V Klycheva et al.
M O Silkina et al.
Ferroptosis is considered a promising strategy for inducing the death of tumor cells. However, the effectiveness of known ferroptosis inducers, such as erastin, is in some cases limited, which stimulates the search for new combined applicat...
Investigating the Role of Membrane Environment in the Recognition of GD2 Ganglioside with Antibodies [0.03%]
探究膜环境在抗体识别GD2神经节苷脂过程中所起的作用
M S Sokolova,V A Zubricheva,E M Rapoport et al.
M S Sokolova et al.
Antibodies to the ganglioside GD2 are used therapeutically, although the mechanism of their interaction with tumor cells antigen is poorly understood. To study the effect of membrane environment on GD2 recognition by antibodies, three synth...
Interaction of Human Peripheral NK Cells with Bacterial Polysaccharides [0.03%]
人外周自然杀伤细胞与细菌多糖的作用机制研究
A A Boyko,L M Kanevskiy,E M Rapoport et al.
A A Boyko et al.
NK cells participate in the antimicrobial immune response. NK cell activation by bacterial polysaccharides (PSs) can occur indirectly through signals from other immune cells or through direct influence of PSs on NK cells via interaction wit...
Epitope Recognized by anti-A,B Antibodies of Blood Group O Individuals as Probed with STD NMR [0.03%]
STD-NMR探察血型O个体抗A、抗B抗体识别的抗原表位
S V Tsygankova,P S Obukhova,T V Tyrtysh et al.
S V Tsygankova et al.
The serum of people with blood group O contains not only classical anti-A and anti-B, but also anti-A,B antibodies, i.e., those whose Fab region equally recognizes both the A and B blood group antigens. The common epitope of the A and B ant...
Glucanosyltransglycosylase Activity of the Glucan-Remodeling Enzyme Bgl2p in the Yeast Cell Wall: Detection and Characterization [0.03%]
酵母细胞壁中的葡萄糖重塑酶Bgl2p的葡聚糖转糖基化酶活性:检测与表征
T S Kalebina,V V Rekstina,N A Drozdov et al.
T S Kalebina et al.
In isolated Saccharomyces cerevisiae cell walls (CWs) obtained without using denaturing agents, Bgl2p demonstrates hydrolysis of the laminaripentaose forming a disaccharide and generates the glucanosyltransglycosylase activity product, lami...
Textural Properties of Pectin-Carrageenan Hydrogels Produced by Food 3D Printing [0.03%]
基于食品3D打印的果胶琼脂糖水凝胶的流变学性质研究
S V Popov,F V Vityazev,N M Paderin et al.
S V Popov et al.
This study investigated the printability and textural properties of 3D-printed pectin-κ-carrageenan hydrogels with varying polysaccharide ratios. Inks with 50 and 60% κ-carrageenan exhibited optimal printability, producing structures cons...
Beyond FERONIA: Gene Expression Profiling Reveals Functional Diversification of Malectin/Malectin-Like Proteins in Tissues with Cell Walls Differing in Pectin Content [0.03%]
FERONIA 之外:基因表达谱分析揭示了细胞壁果胶含量不同组织中麦拉克汀/麦拉克汀-like蛋白功能多样化
N Syrchina,N Mokshina,N Petrova et al.
N Syrchina et al.
Malectin and malectin-like proteins (M/MLPs) form one of the largest plant lectin families, yet the carbohydrate specificity of most members remains largely unexplored. FERONIA, a receptor-like kinase and key regulator of cell expansion, is...
Isolation and Characterization of Halophilic Bacteria of the Halomonadaceae Family, Promising Producers of Extracellular Polysaccharides [0.03%]
盐杆菌科耐盐嗜极端细菌的分离和表征——一种有前景的产生胞外多糖菌种
Yu P Fedonenko,V S Grinev,N S Velichko et al.
Yu P Fedonenko et al.
Exopolysaccharide (EPS) production is one of the key mechanisms of bacterial survival in hypermineralized environments. Representatives of the Halomonadaceae family are recognized as basic organisms for next-generation industrial biotechnol...