E E Gubar,T V Korotaeva,L D Vorobyova et al.
E E Gubar et al.
To develop a unified diagnostic algorithm for axial psoriatic arthritis (axPsA). MATERIALS AND METHODS. : A total of 122 patients with psoriatic arthritis (PsA), duration less than 10 years, were included in the study according to CASPAR cr...
The Effect of RNA Tertiary Structure on Trans-Splicing of the mod(mdg4) Gene in Drosophila melanogaster [0.03%]
RNA三级结构对果蝇mod(mdg4)基因反式剪接的影响
Iu V Soldatova,O Beginyazova,P G Georgiev et al.
Iu V Soldatova et al.
Trans-splicing is a rare variant of the splicing process, wherein exons are joined between different pre-mRNAs. This mechanism enables the formation of a broad spectrum of mRNAs encoded by a single locus. The most prominent example in Droso...
Evaluation of Effectiveness of Long-Term Therapy with Russian Rituximab Biosimilar (Acellbia) in Sjogren's Disease in Real Clinical Practice [0.03%]
俄罗斯利妥昔单抗仿制药(Acellbia)治疗干燥综合征长期疗效的实临床评价研究
B D Chaltsev,V I Vasilyev,A V Torgashina et al.
B D Chaltsev et al.
to evaluate the effectiveness of long-term therapy with Russian rituximab (RTX) biosimilar in Sjögren's disease (SjD) in real-life clinical practice. MATERIALS AND METHODS: -The retrospective study included 53 patients with SjD (Russian 20...
Efficacy of Olokizumab in Treating Comorbid Depression in Patients with Rheumatoid Arthritis: Results of a Single-Center Randomized Controlled Trial [0.03%]
奥洛克珠单抗治疗类风湿关节炎共病抑郁的疗效：一项单中心随机对照试验的结果
T A Lisitsyna,A A Abramkin,D Yu Veltishchev et al.
T A Lisitsyna et al.
Interleukin (IL)-6 plays an important role in the pathogenesis of comorbid rheumatoid arthritis (RA) depression. IL-6 inhibitors used to treat patients with RA may also have an antidepressant effect. THE OBJECTIVE-: of this study is to eval...
The Late Boundary Complex (LBC) Selectively Binds the Fab-7/Fab-8 Boundaries, but not Fab-6 or Mcp, in the Abd-B Regulatory Region of Drosophila melanogaster [0.03%]
后来的边界复合物（LBC）特异性地结合果蝇Abd-B调控区的Fab-7 / Fab-8边界，而不是Fab-6或Mcp
A N Ibragimov,O V Kyrchanova,P G Georgiev et al.
A N Ibragimov et al.
Boundary elements in the Drosophila Bithorax complex partition the Abd-B regulatory landscape into autonomous domains that require insulation and boundary bypass. We surveyed Large Boundary Complex (LBC) occupancy across Abd-B boundaries an...
Features of Biochemical and Hematological Parameters and Chromosomal Disorders in Lymphocytes of Aging Primates of the Kurchatovsky Complex of Medical Primatology [0.03%]
库恰特夫斯基医学灵长类研究中心衰老猴淋巴细胞生化、血液学参数及染色体异常的特征
O P Chzhu,N S Rudenko,D E Araviaashvili et al.
O P Chzhu et al.
Aging is a key challenge for modern society. In particular, brain aging is accompanied by chronic inflammation, depletion of energy potential, and an increased level of oxidative stress, with changes in blood composition playing a special r...
Pathomorphological Features of Lung Damage Caused by Infection with Various Variants of SARS-CoV-2 in Humanized Model Animals [0.03%]
人源化模式动物感染各种变异株后肺损伤的病理特征分析
A S Chernov,V A Kazakov,I S Gogleva et al.
A S Chernov et al.
The genotypic variability of the SARS-CoV-2 virus is extremely high, and the emergence of new strains raises concerns about their possible high virulence and ability to bypass responses of the body's immune system induced by previous infect...
Expression of Antioxidant Defense Genes Determines Synergistic Ferroptosis Induction by the Combination of Erastin and Omega-3 Docosahexaenoic Acid in Prostate Cancer Cells [0.03%]
泛酸防御基因表达决定尔塞丁和欧米茄-3二十二碳六烯酸联合诱导前列腺癌细胞铁死亡的协同效应
M O Silkina,T A Kulagin,K V Klycheva et al.
M O Silkina et al.
Ferroptosis is considered a promising strategy for inducing the death of tumor cells. However, the effectiveness of known ferroptosis inducers, such as erastin, is in some cases limited, which stimulates the search for new combined applicat...
Investigating the Role of Membrane Environment in the Recognition of GD2 Ganglioside with Antibodies [0.03%]
探究膜环境在抗体识别GD2神经节苷脂过程中所起的作用
M S Sokolova,V A Zubricheva,E M Rapoport et al.
M S Sokolova et al.
Antibodies to the ganglioside GD2 are used therapeutically, although the mechanism of their interaction with tumor cells antigen is poorly understood. To study the effect of membrane environment on GD2 recognition by antibodies, three synth...
Interaction of Human Peripheral NK Cells with Bacterial Polysaccharides [0.03%]
人外周自然杀伤细胞与细菌多糖的作用机制研究
A A Boyko,L M Kanevskiy,E M Rapoport et al.
A A Boyko et al.
NK cells participate in the antimicrobial immune response. NK cell activation by bacterial polysaccharides (PSs) can occur indirectly through signals from other immune cells or through direct influence of PSs on NK cells via interaction wit...