Composition and Content of Fatty Acids in Artemia Cyst (Artemia spp.) from Lakes of Southern Siberia as an Indicator of Biochemical Value for Fish Feed [0.03%]
南西伯利亚湖泊卤虫(Artemia spp.)卵脂肪酸组成和含量的测定及其作为鱼类饲料生化价值指标的意义
A E Rudchenko,V A Karpov,O S Dimenko et al.
A E Rudchenko et al.
For the first time, the composition and fatty acid content of Artemia spp. cysts from three hypersaline lakes in Southern Siberia were analyzed. The fatty acid composition of decapsulated Artemia cysts varied significantly between the studi...
Real-World Retention Rate, Effectiveness, and Safety of Netakimab in the Treatment of Patients with Ankylosing Spondylitis: Two-Year Results of the Real Word Evidence LIBRA Study [0.03%]
净达奇单抗治疗强直性脊柱炎患者的真实世界留存率、有效性和安全性：LIBRA研究2年结果
Sh F Erdes,V I Mazurov,I Z Gaidukova et al.
Sh F Erdes et al.
of the study was to obtain data on the safety of netakimab (NTK) in a population of patients with ankylosing spondylitis (AS), including various somatic diseases, as well as to assess treatment retention during 2 years of observation in rea...
Enhancement of Rotenone Cytotoxicity in the Presence of Bach1 Inhibitors [0.03%]
Bach1抑制剂可增强Rotenone细胞毒性作用
S V Nikulin,D Olkhovik,A V Razumovskaya et al.
S V Nikulin et al.
A novel trend in anticancer therapy is based on the combination of cytotoxic and metabolic drugs. Bach1 is a transcription factor activating glycolysis and increasing proliferation and metastatic potential in cancer cells. The cytotoxic eff...
ENY2 Protein Is Present at the Histone Locus Body HLB As Part of Complexes with Different Functions in Transcription and mRNA Export [0.03%]
ENY2蛋白作为转录和mRNA出口中具有不同功能的复合物的一部分存在于组蛋白基因区体中
S Y Ushakova,S G Georgieva,M M Kurshakova
S Y Ushakova
The evolutionarily conserved transcription factor ENY2 is a component of several distinct complexes that regulate various stages of gene expression: the SAGA transcription coactivator, the THO transcription elongation complex involved in mR...
Determinants of DNA Binding by Plant Homologs of 3-Methyladenine-DNA Glycosylase [0.03%]
植物3-甲基腺嘌呤-DNA glycosylase同源物DNA结合的决定因素
D V Petrova,L M Kulishova,A V Endutkin et al.
D V Petrova et al.
Tag proteins, widespread among prokaryotes, are DNA glycosylases that participate in the repair of alkylated DNA excising 3-methyladenine. Among eukaryotes, Tag homologs are found only in plants, but they have not yet been characterized. He...
Blockers of Acetylcholine Receptors Affect the Hypotensive Effect of the Central Loop Fragment of the WTX Toxin [0.03%]
乙酰胆碱受体阻滞剂影响外周神经毒素WXT中央环肽的降压效果
M S Severyukhina,A M Ismailova,E R Shaykhutdinova et al.
M S Severyukhina et al.
We previously demonstrated that fragments of the central loop of the non-conventional toxin WTX reduce blood pressure in rats and inhibit certain nicotinic acetylcholine receptor subtypes [10]. In the present study, we examined the effects ...
Efficacy and Safety of Rapid Dose Escalation of Methotrexate in Rheumatoid Arthritis (Results of the Multicenter METEOR Study) [0.03%]
甲氨蝶呤剂量快速递增治疗类风湿性关节炎的疗效和安全性：多中心METEOR研究结果
V N Amirdzhanova,E Yu Polischuk,O N Anoshenkova et al.
V N Amirdzhanova et al.
The aim of the study was to analyze the effectiveness and tolerability of subcutaneous methotrexate (sc MTX) (METHORTRIT; sc ROMPHARM Company) in RA patients with high disease activity with rapid dose escalation, to assess their quality of ...
Study of the Role of Transvection in the Regulation of Initiators That Determine Activity of the Regulatory Domains of the Drosophila melanogaster Abd-B Gene [0.03%]
关于反式作用在调节决定果蝇Abd-B基因调控域活性的启动子中的作用的研究
V O Dubrovskaya,E N Kozlov,P G Georgiev et al.
V O Dubrovskaya et al.
The iab-5 domain regulates transcription of the Abdominal-B (Abd-B) gene in A5 and A6 segments throughout Drosophila development. The iab-5 domain contains an initiator, which determines domain activity, and two enhancers that activate Abd-...
Trans-Splicing Enhances Processivity of RNA Polymerase II and Suppresses Polyadenylation Signals [0.03%]
反向剪接促进RNA聚合酶II的进程子并抑制多腺苷酸化信号
Iu V Soldatova,O Beginyazova,L S Melnikova et al.
Iu V Soldatova et al.
Trans-splicing, the process where exons from two different pre-mRNA molecules are joined, is an efficient mechanism for generating diverse isoforms encoded by a single locus. This process has been most thoroughly studied in the mod(mdg4) lo...
The Role of D/H Isotope Exchange in Stabilizing Trinucleotide Repeat Expansions in the CAG Tract of the ATXN2 Gene [0.03%]
氘氢同位素交换在稳定ATXN2基因CAG轨迹三核苷酸重复扩增中的作用
A A Dorohova,I M Chernukha,L V Fedulova et al.
A A Dorohova et al.
CAG repeats in the first exon of the ATXN2 gene play a key role in the development of a number of neurodegenerative diseases. Understanding the mechanisms underlying CAG tract expansions and the factors influencing them could lead to the de...