The imbalance between regulatory memory B cells reveals possible pathogenesis involvement in pediatric immune thrombocytopenia [0.03%]
儿童免疫性血小板减少症中调节性记忆B细胞的失衡可能参与了其发病机制
Junyue Fang,Li Lin,Dijin Lin et al.
Junyue Fang et al.
Introduction: CD19+CD24hiCD38hi regulatory B cells (Bregs) and CD19+CD27+ memory B cells (Bmems) are B cell subsets with specific immunoregulatory properties. In this study, the balance of these subsets was investigated in pediatric immune ...
Time course of peripheral blood count recovery during induction chemotherapy for childhood acute lymphoblastic leukemia [0.03%]
儿童急性淋巴细胞白血病诱导化疗外周血象恢复的时序规律研究
Julie Dalsgaard Grunnan,Steen Rosthøj
Julie Dalsgaard Grunnan
Introduction: Children with newly diagnosed acute lymphoblastic leukemia (ALL) present with low peripheral blood counts caused by bone marrow replacement. The recovery of counts during induction chemotherapy is not well described. Material ...
Interactions of unstable hemoglobin Rush with thalassemia and hemoglobin E result in thalassemia intermedia [0.03%]
不稳定血红蛋白Rush与地中海贫血和血红蛋白E的相互作用导致中间型地中海贫血
Kai Huang,Shijun Ge,Wei Yi et al.
Kai Huang et al.
Background: The clinical consequences and significance of many unstable hemoglobins interacting with other hemoglobinopathies remain unrecognized. Here we first explore molecular and hematological characterizations of previously undescribed...
Upfront autologous hematopoietic stem cell transplantation in patients with high-risk stage III to IV Hodgkin lymphoma: a multicenter retrospective cohort study [0.03%]
高危III-IV期霍奇金淋巴瘤患者自体造血干细胞移植的诱导序贯移植方案：一项多中心回顾性队列研究
Li Gao,Xixi Xiang,Cheng Zhang et al.
Li Gao et al.
Background/objective: Nearly 30% of patients with advanced-stage Hodgkin lymphoma (HL) are not cured. We should better control tumors with initial treatment for patients with advanced stage HL whose interim positron emiss...
Qi-Guo Zhang,Jing Wang,Wen-Yu Gong et al.
Qi-Guo Zhang et al.
Objectives and importance: Chronic neutrophilic leukemia (CNL) is a distinct myeloproliferative neoplasm with a high prevalence (>80%) of mutations in the colony-stimulating factor 3 receptor (CSF3R); these mutations activate the receptor, ...
Clinicopathologic significance and therapeutic implication of de novo CD5+ diffuse large B-cell lymphoma [0.03%]
新型CD5⁺弥漫性大B细胞淋巴瘤的临床病理意义及治疗意义
Huifen Tang,Hui Zhou,Juying Wei et al.
Huifen Tang et al.
Background: Various subsets of diffuse large B-cell lymphoma(DLBCL) are distinguished based on molecular and immunohistochemical features. As we know, CD5 is a pan-T-cell surface marker and is seldom expressed in DLBCL. L...
Advances in the treatment and prognosis of anaplastic lymphoma kinase negative anaplastic large cell lymphoma [0.03%]
ALK阴性间变大细胞淋巴瘤的治疗和预后进展
Xiaoli Wang,Jingjing Wu,Mingzhi Zhang
Xiaoli Wang
Anaplastic lymphoma kinase negative anaplastic large cell lymphoma (ALK- ALCL) is a definite entity in the WHO 2016 Classification that represents 2-3% of non-Hodgkin lymphoma (NHL) and 12% of T-cell NHL cases. ALK- ALCL lacks ALK protein e...
Beta-thalassemia: renal complications and mechanisms: a narrative review [0.03%]
β-地中海贫血的肾脏并发症及机制：综述
Christos Demosthenous,Efthymia Vlachaki,Chrysa Apostolou et al.
Christos Demosthenous et al.
Objectives: Beta-thalassemias are a group of recessively autosomal inherited disorders of hemoglobin synthesis, which, due to mutations of the beta-globin gene, lead to various degrees of defective beta-chain production, ...
Compound heterozygous mutations Glu502Lys and Met527Thr of the FXII gene in a patient with factor XII deficiency [0.03%]
FXII基因化合物杂合突变（E502K和M527T）所致凝血因子十二缺乏症患者的临床特征及实验室特点分析
Haiyue Zhang,Siqi Liu,Chanchan Lin et al.
Haiyue Zhang et al.
Objective: To study the gene mutation of human coagulation factor XII (FXII) in a Chinese family with FXII deficiency and it will help us to understand the pathogenesis of this type of disease. ...
Clinical characteristics and prognostic factors of primary extranodal classical Hodgkin lymphoma: a retrospective study [0.03%]
原发性结外经典型霍奇金淋巴瘤的临床特征和预后因素：一项回顾性研究
Mingzi Yang,Lingyan Ping,Weiping Liu et al.
Mingzi Yang et al.
Objectives: To analyze the clinical characteristics and prognosis of primary extranodal classical Hodgkin lymphoma (PE-cHL). Methods: C...