Efficacy and safety of TPO-RA combined with sirolimus in the treatment of relapsed immune thrombocytopenia [0.03%]
Dan Wang,Jia Liu,Aoxue Tan et al.
Dan Wang et al.
Background: Relapsed immune thrombocytopenia (ITP) poses challenges in treatment. Thrombopoietin receptor agonists (TPO-RAs) are recommended as second-line therapy, but the efficacy of monotherapy is limited to about 60%....
U-shaped association of red cell distribution width to platelet count ratio and prognosis in diffuse large B-cell lymphoma treated with rituximab-based therapy [0.03%]
Jiabin Pan,Luhui Lin,Suoyu Chen et al.
Jiabin Pan et al.
Objectives: To examine the nonlinear association between the red cell distribution width to platelet count ratio (RPR) and the prognosis of diffuse large B-cell lymphoma (DLBCL) patients treated with rituximab-based thera...
Association between red cell distribution width to albumin ratio and all-cause mortality in critically ill patients with myelodysplastic syndrome: a retrospective cohort study [0.03%]
Zicong Huang,Shan Liu,Zhi Guo
Zicong Huang
Background: The red cell distribution width to albumin ratio (RAR) has emerged as a novel, easily calculated biomarker demonstrating prognostic value across various diseases. However, the relationship of RAR for all-cause...
The correlation between cardiac T2*MRI and B-Type natriuretic peptides in patients with transfusion-dependent anemias and systemic iron overload: a systematic review and meta-analysis [0.03%]
Mohamad Amin Kharaghani,Reza Samiee,Amirhossein Shahsavand et al.
Mohamad Amin Kharaghani et al.
Objectives: Systemic iron overload in transfusion-dependent anemias leads to progressive myocardial iron accumulation, a major cause of morbidity and mortality. This study evaluated the relationship between cardiac T2* ma...
High body-mass index and multiple myeloma risk: insights from the global burden of disease 2021 study and identification of core target genes [0.03%]
高体重指数与多发性骨髓瘤风险:来自2021年全球疾病负担研究的见解及核心靶基因识别
Li Zhou,Yingzhe Zhang,Jiwei Li
Li Zhou
Background: High Body mass index (BMI) is a well-established risk factor for various hematological malignancies. However, the relation and mechanism between high BMI and multiple myeloma remain largely unknown. ...
Impact of frailty tools on outcomes in myeloma: MRP and simplified index predict survival but differ in infection risk stratification [0.03%]
脆弱工具对多发性骨髓瘤预后的影响:MRP和简化指数可预测生存率但不能区分感染风险分级
Shaoli Zhang,Linyu Li,Weiwei Tian et al.
Shaoli Zhang et al.
Objective: To explore the application efficacy of the UK Myeloma Alliance Risk Stratification (MRP) and the Simplified Frailty Index (FI) in patients with newly diagnosed multiple myeloma (NDMM). ...
Prognostic factors and clinical outcomes in pediatric Langerhans Cell Histiocytosis: a retrospective cohort study on event-free survival [0.03%]
儿童朗格汉斯细胞组织细胞增生症的预后因素和临床结局:关于无事件生存率的回顾性队列研究
Kang Wang,Chen Wang,Hua Zhu et al.
Kang Wang et al.
Objectives: Langerhans Cell Histiocytosis (LCH) is an inflammatory myeloid neoplasm with heterogeneous outcomes. This study aimed to identify independent risk factors influencing event-free survival (EFS) in pediatric LCH...
Neutrophil extracellular trap-related genes in PTCL: identification, prognosis and drug interaction prediction via bioinformatics-machine learning [0.03%]
利用生物信息学-机器学习鉴定外周T细胞淋巴瘤中与NETs相关的基因及其预后和药物相互作用预测
Jing Chen,Fanjun Cheng,Jun Fang
Jing Chen
Objective: This study aimed to identify neutrophil extracellular trap-related genes (NET-RGs), explore their prognostic significance, and predict drug interactions in peripheral T-cell lymphoma (PTCL). ...
Post-transplant cyclophosphamide as graft-versus-host disease prophylaxis for matched related donor hematopoietic stem cell transplantation in acute leukemia: a systematic review and meta-analysis [0.03%]
异基因造血干细胞移植后环磷酰胺预防急性白血病患者移植物抗宿主病的系统评价和 Meta 分析
Amirhossein Shahsavand,Shayan Forghani,Reza Samiee et al.
Amirhossein Shahsavand et al.
Although allogeneic hematopoietic stem cell transplantation (HSCT) offers curative potential for acute leukemia, graft-versus-host disease (GVHD) remains a major obstacle to optimal clinical outcomes. Evidence for post-transplant cyclophosp...
Whole transcriptome sequencing reveals differences in the pathogenesis of myelodysplastic syndromes and acute myeloid leukemia [0.03%]
全转录组测序揭示了骨髓增生异常综合征和急性髓系白血病发病机制的差异
Miao Zhou,Tongyu Li,Yun Li et al.
Miao Zhou et al.
Objectives: Myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) are closely related hematologic malignancies. However, the transcriptomic distinctions between them are not fully elucidated. This study aimed to...