Cancer cell plasticity and therapeutic resistance: mechanisms, crosstalk, and translational perspectives [0.03%]
癌症细胞的可塑性和治疗抵抗性：机制、相互作用和转化医学观点
Saeid Ghorbian
Saeid Ghorbian
Resistance to targeted cancer therapies is a significant barrier to favorable treatment outcomes. Malignant cells can tolerate and resist drug treatments due to their biological flexibility. Specifically, slow-cycling drug-resistant cells m...
Analysis of spermidine's effect on coronary heart disease risk using bidirectional Mendelian randomization and LC-MS/MS [0.03%]
利用双向孟德尔随机化和LC-MS/MS分析精胺对冠心病风险的影响
Tianyi Wang,Li Lin,Yaodong Ding et al.
Tianyi Wang et al.
Background: This study examines the causal relationship between spermidine levels and coronary artery disease (CHD) risk using a bidirectional Mendelian Randomization (MR) approach. ...
Bibliometric and visual analysis of palliative care in colorectal cancer research from 2015 to April 2025 [0.03%]
2015-2025年结直肠癌姑息治疗研究的 bibliometric 和可视化分析
Xiaohui Zhang,Liangliang Li,Anxia Li
Xiaohui Zhang
Objective: Palliative care, as a treatment method for incurable diseases, can alleviate patients’ pain and improve their quality of life(QOL) to a certain extent. This treatment method is also common in the treatment of ...
miR-423-5p mediates LINC00886 regulation of ovarian cancer aggressiveness and immune evasion via the TLR4/Myd88/NF-κB/PD-L1 pathway [0.03%]
microRNA-423-5p介导LINC00886通过TLR4/Myd88/NF-κB/PD-L1途径调节卵巢癌的侵袭性和免疫逃逸
Na Du,Xiaowen Zhang,Chao He et al.
Na Du et al.
Background: Ovarian cancer has poor treatment outcomes. This study aims to explore the clinical importance of LINC00886 and its effects on cancer cell behavior in ovarian cancer, potentially offering a new therapeutic tar...
miR-671-5p as a diagnostic biomarker and therapeutic target in periodontitis via THBS1 regulation [0.03%]
通过THBS1调节在牙周炎中作为诊断生物标志物和治疗靶点的miR-671-5p研究
Shan Huang,Wei Cheng,Jianlan Deng
Shan Huang
Background: Early diagnosis and therapeutic targeting of periodontitis remain challenging. This study aimed to investigate the clinical relevance and mechanistic role of miR-671-5p in pathogenesis of periodontitis. ...
The FOXD1/NAT10 positive feedback loop drives nasopharyngeal carcinoma progression [0.03%]
FOXD1/NAT10正反馈环路驱动鼻咽癌进展
Leifeng Liu,Qizhu Chen,Yiling Li et al.
Leifeng Liu et al.
Background: Nasopharyngeal carcinoma (NPC) is a malignant epithelial tumor. N4-acetylcytidine (ac4C) modification regulates mRNA stability and contributes to tumorigenesis. FOXD1, a crucial transcription factor, acts as a...
Identification of a KRT9 gene variant and preimplantation genetic diagnosis in a Chinese family with KRT9-palmoplantar epidermal differentiation disorder [0.03%]
KRT9基因变异的鉴定及其在棘皮松解角化病家系中的胚胎种植前遗传学诊断研究
Dan Lin,Na Lin,Yao Zhou et al.
Dan Lin et al.
Objective: To investigate a Chinese family with epidermolysis bullosa palmoplantar keratosis, analyze the mutation loci in this family lineage, and perform preimplantation genetic testing using assisted reproductive techn...
Unveiling the mechanisms of yanhusuo's therapeutic effects in neuropathic pain through network pharmacology, single-cell RNA sequencing, and molecular docking [0.03%]
基于网络药理学、单细胞测序及分子对接探究延胡索治疗神经病理性疼痛的机制研究
Rui Liu,Min Yu,Kaihan Zhuang et al.
Rui Liu et al.
Background: Current therapeutic strategies for neuropathic pain (NP) encompass pharmacological agents, physical modalities, psychological support, and interventional procedures, which aim to mitigate inflammation, enhance...
Correction: Qingjie Fuzheng granules attenuate cancer cachexia by restoring gut microbiota homeostasis and suppressing IL-6/NF-κB signaling in colorectal adenocarcinoma [0.03%]
清结扶正颗粒通过恢复肠道菌群稳态和抑制白介素-6/核因子-κB信号通路治疗结肠腺癌恶病质（纠错）
Yishun Jin,Lisha Lu,Hangju Hua et al.
Yishun Jin et al.
Published Erratum
Hereditas. 2025 Sep 17;162(1):181. DOI:10.1186/s41065-025-00577-3 2025
Hua-Sheng Chiu
Hua-Sheng Chiu
This Editorial introduces my research background as the new Non-coding RNA Section Editor at Hereditas and serves as a call for submissions for the special collection, "Single-Cell Multi-Omic Analysis of Cancer Interactome". Single-cell mul...