Shengjiang Powder alleviates oxidative stress damage and fibrosis in mice with atherosclerosis concurrent with non-alcoholic fatty liver disease [0.03%]
圣姜粉对动脉粥样硬化合并非酒精性脂肪肝病小鼠氧化应激损伤及纤维化的影响
Jia He,Bingjiu Lu,Yan Zhang et al.
Jia He et al.
Objective: To investigate the effects of "Shengjiang Powder", a representative formula for "simultaneous treatment of liver and heart," on liver tissue inflammation and fibrosis in mice with atherosclerosis(AS) concurrent...
LncRNA MEG8 promotes deep vein thrombosis by sponging miR-296-5p to regulate human umbilical vein endothelial cells [0.03%]
长链非编码RNA MEG8通过海绵吸附miR-296-5p来调节人脐静脉内皮细胞以促进深静脉血栓形成
Jiaqi Zhang,Menglan Li,Xingbang Na
Jiaqi Zhang
Aim: This study explored the diagnostic value and molecular mechanism of lncRNA MEG8 in deep vein thrombosis (DVT). Methods: This study...
In vitro culture media type impacts gene expression in the freshwater mussel Lampsilis siliquoidea (Bivalvia: Unionidae) [0.03%]
体外培养基类型影响淡水贻贝Lampsilis siliquoidea（瓣鳃动物： unionidae）的基因表达
Kaitlin E Ulin,Alexandra R Phelps,Chase J Ellis et al.
Kaitlin E Ulin et al.
Artificial propagation is an important conservation technique to mitigate the loss of native freshwater mussel diversity. In vitro propagation is an alternative method of metamorphosing freshwater mussel larvae (glochidia) to juveniles with...
The diagnostic and prognostic value of miR-188-5p in intracranial aneurysm (IA) and its potential regulatory mechanism [0.03%]
miR-188-5p在颅内动脉瘤诊断、预后价值及其潜在调控机制研究
Liujia Ma,Lei Shi,Wenjie Tang
Liujia Ma
Background and objectives: As the etiology of intracranial aneurysm (IA) remains uncertain and unruptured IA management continues to be debated, investigating biomarkers of the disease remains critical. This study thus ev...
Downregulation of KHSRP enhances carboplatin sensitivity in non-small cell lung cancer [0.03%]
KHSRP下调可增强顺铂对非小细胞肺癌的敏感性
Bao Wen,Shuguang Bao,Yanqing Gao et al.
Bao Wen et al.
Background: Carboplatin resistance represents a critical therapeutic challenge in non-small cell lung cancer (NSCLC) treatment. Although KHSRP has been implicated in lung cancer progression, its molecular mechanisms and i...
The synergistic antitumor effects of psoralidin and cisplatin in gastric cancer by inducing ACSL4-mediated ferroptosis [0.03%]
补骨脂定通过ACSL4介导的铁死亡与顺铂在胃癌中产生的协同抗肿瘤作用
Ling Yao,Jinhua Yan,Lihong Gan et al.
Ling Yao et al.
Objective: Cisplatin (DDP) is the major chemotherapeutic drug used to treat gastric cancer (GC). However, DDP-associated side effects and resistance chemoresistance have limited its clinical application. Psoralidin (PSO) ...
Downregulation of PDIA4 inhibits proliferation and migration in human oral squamous cell carcinoma [0.03%]
PDIA4下调抑制人舌鳞癌细胞增殖和迁移的作用及机制研究
Yue Hu,Wei Zhang,Fuyu Zhang et al.
Yue Hu et al.
Background: Protein disulfide isomerase family A member 4 (PDIA4), a member of the protein disulfide isomerase family, has been associated with the progression of cancer. Nevertheless, its specific function in oral squamo...
Identification of metabolic reprogramming-associated biomarkers in endometriosis through integrated bioinformatics analysis [0.03%]
通过集成生物信息学分析识别与代谢重组相关的子宫内膜异位症生物标志物
Jia Zhen,Ziyuan Zhao,Qi Wu et al.
Jia Zhen et al.
Background: Endometriosis (EMs), a common gynecological disorder, involves complex molecular mechanisms. Metabolic reprogramming (MR) has been recognized as a hallmark of EMs, contributing to lesion survival and immune mi...
The microRNAs landscape of luminal B breast cancer cells in a three-dimensional microenvironment [0.03%]
三维微环境中腔内B型乳腺癌细胞的microRNAs图谱
Stephanie I Nuñez-Olvera,Lorena Aguilar-Arnal,Jonathan Puente-Rivera et al.
Stephanie I Nuñez-Olvera et al.
Background: Three-dimensional (3D) culture captures key features of tumor architecture and microenvironmental signaling. Because microRNAs (miRNAs) are central post-transcriptional regulators, we asked whether 3D growth w...
Therapeutic effects of Bushen Chushi formula on knee osteoarthritis via modulation of MAPK/SLC7A11/GPX4 signaling in rats [0.03%]
补肾除湿方通过调节MAPK/SLC7A11/GPX4信号通路改善膝骨关节炎的系统研究
Yuanyuan Li,Hai Tang,Mingjiang He et al.
Yuanyuan Li et al.
Objective: The aim of this study is to evaluate the therapeutic efficacy of Bushen Chushi Formula (BSCSF) in a rat model of knee osteoarthritis (KOA), with a focus on the modulation of ferroptosis-related signaling pathwa...