Specific human leucocyte antigen-DQ risk epitope mismatches are associated with chronic lung allograft dysfunction after lung transplantation [0.03%]
特定的人类白细胞抗原-DQ风险表位不匹配与肺移植后的慢性肺移植物功能障碍相关
Samantha L Ennis,Nick Olsen,Winnie W Y Tong et al.
Samantha L Ennis et al.
A high-risk epitope mismatch (REM) (found in DQA1∗05 + DQB1∗02/DQB1∗03:01) is associated with de novo donor specific antibodies after lung transplantation (LTx). Chronic lung allograft dysfunction (CLAD) remains a barrier to LTx survival...
Insights from immunoproteomic profiling of a rejected full-face transplant [0.03%]
面部移植排异反应的免疫蛋白质组学分析见解
Catherine A A Lee,Diana Wang,Martin Kauke-Navarro et al.
Catherine A A Lee et al.
Vascularized composite allografts (VCAs) of faces and extremities are subject to chronic rejection that is incompletely understood. Here we report on immunoproteomic evaluation of a full facial VCA removed 88 months after transplantation du...
Organ recovery from preterm infants following circulatory death: The tiniest package might hold the greatest gift [0.03%]
早产儿循环死亡后的器官获取：最小的身躯可能蕴藏着最珍贵的礼物
Thomas A Nakagawa
Thomas A Nakagawa
TNX-1500, a crystallizable fragment-modified anti-CD154 antibody, prolongs nonhuman primate cardiac allograft survival [0.03%]
一种可结晶片段改良的抗CD154抗体(TNX-1500)延长非人灵长类心脏移植物存活时间
Shuhei Miura,Zahra A Habibabady,Franziska Pollok et al.
Shuhei Miura et al.
Blockade of the CD40/CD154 T cell costimulation pathway is a promising approach to supplement or replace current clinical immunosuppression in solid organ transplantation. We evaluated the tolerability and activity of a novel humanized anti...
Efficacy of ceftazidime-avibactam in solid organ transplant recipients with bloodstream infections caused by carbapenemase-producing Klebsiella pneumoniae [0.03%]
卡泊霉素耐药肺炎克雷伯菌所致移植器官受者血流感染的头孢他啶-阿维巴坦疗效分析
Elena Pérez-Nadales,Mario Fernández-Ruiz,Alejandra M Natera et al.
Elena Pérez-Nadales et al.
We aimed to compare the efficacy of ceftazidime-avibactam (CAZ-AVI) versus the best available therapy (BAT) in solid organ transplant (SOT) recipients with bloodstream infection caused by carbapenemase-producing Klebsiella pneumoniae (CPKP-...
The future of organ donation in Europe: Is there a role for organ recovery centers? [0.03%]
欧洲器官捐献的未来：器官获取中心的作用几何？
Frank J M F Dor,Robert J Porte,Derek M Manas
Frank J M F Dor
Christina Papageorge,Sandeep Sharma,Seetharam Chadalavada et al.
Christina Papageorge et al.
Trends in Reported Babesiosis Cases - United States, 2011-2019 [0.03%]
2011-2019年美国 babesiosis 报告病例的流行趋势
Megan Swanson,Amy Pickrel,John Williamson et al.
Megan Swanson et al.
Liver transplantation for alcohol-associated liver disease: A call for national standards of best practices to monitor and bridge disparities in access and outcomes [0.03%]
酒精相关性肝病的肝脏移植：建立国家最佳临床实践标准以监测和缓解供体获取及预后不平等的呼吁
Brian P Lee,Norah A Terrault
Brian P Lee
Early (ie, without a mandated abstinence period) liver transplantation for alcohol-associated liver disease is the fastest-growing indication for liver transplantation in the United States. Despite widespread adoption, there is no standardi...
TNX-1500, a crystallizable fragment-modified anti-CD154 antibody, prolongs nonhuman primate renal allograft survival [0.03%]
一种可结晶片段修饰的抗CD154抗体(TNX-1500)延长非人灵长类肾脏移植物存活时间
Grace Lassiter,Ryo Otsuka,Takayuki Hirose et al.
Grace Lassiter et al.
The blockade of the CD154-CD40 pathway with anti-CD154 monoclonal antibody has been a promising immunomodulatory approach to prevent allograft rejection. However, clinical trials of immunoglobulin G1 antibodies targeting this pathway reveal...