Integrating Deceased and Living Donation: Six-Year Outcomes of the Italian Deceased-Donor-Initiated Kidney Paired Exchange (DEC-K) Program [0.03%]
意大利脑死亡供肾者发起的肾交换项目的六年的结果(DEC-K项目)
Caterina Di Bella,Umberto Maggiore,Pamela Fiaschetti et al.
Caterina Di Bella et al.
Using a deceased donor (DD) to initiate living-donor (LD) exchange chains can expand access to kidney transplantation in recipients with an HLA or ABO incompatible living donor. The Italian DD-initiated Kidney Paired Exchange (DEC-K) progra...
Fused IL-12-TIGIT immunocytokines enable spatially targeted modification of immune responses [0.03%]
融合型IL-12-TIGIT免疫细胞因子能够实现对免疫反应的空间靶向调节
E M Gillis Buck,S R Aghi,J M Gardner
E M Gillis Buck
A Comparative Study of Once-Daily versus Twice-Daily Tacrolimus in Deceased Donor Kidney Transplant Recipients: A National Cohort Analysis [0.03%]
尸体供者肾脏移植受者的每日一次与每日两次他克莫司的比较研究——一项全国队列分析
Gaurav Gupta,Ahmet B Gungor,Maryam Emami Neyestanak et al.
Gaurav Gupta et al.
The comparative real-world effectiveness of extended-release (Life-Cycle Pharma Tacrolimus [LCPT]) versus immediate-release (IR) tacrolimus formulations in deceased-donor kidney transplantation remains incompletely characterized. We conduct...
Beyond Trough Levels: Tacrolimus Dose Requirements and Individualized Monitoring in Kidney Transplantation [0.03%]
环孢素剂量需求及肾脏移植受者的个体化监测超出低谷水平：Tacrolimus剂量需求及个体化监测在肾移植中的作用
Stefan Reuter,Dirk R J Kuypers
Stefan Reuter
Tacrolimus trough concentrations are essential after kidney transplantation but do not describe the dose required to achieve them. The concentration-to-dose (C/D) ratio adds this denominator and provides a low-cost, time-dependent dose-requ...
Improvements in Survival after Delisting without Transplant Signal Potential Data Quality Issue [0.03%]
移除供肝分配列表后的生存改善或预示数据质量问题的潜在信号
Maria Masotti,Daniel Y Johnson,Jessica R Golbus et al.
Maria Masotti et al.
Knowing the fate of patients removed from waiting lists without transplant is critical for evaluating the equity and efficiency of the US transplant system, but transplant centers are not required to report deaths after delisting. Our aim w...
Human lymphoid organoids as a platform for interrogating adaptive immunity, tolerance, and alloimmunity [0.03%]
人淋巴器官样组织作为研究适应性免疫、耐受性和移植物抗宿主病的平台
Lucas P Wachsmuth,Seleipiri Charles-Norfleet,James Gardner
Lucas P Wachsmuth
Designing CD8 T-cell mRNA vaccines targeting the viral large T antigen to prevent BK polyomavirus disease after kidney transplantation [0.03%]
设计靶向病毒大型T抗原的CD8 T细胞mRNA疫苗以预防肾移植后BK多瘤病毒病
Maud Wilhelm,Océane M Follonier,Anne Geng et al.
Maud Wilhelm et al.
BK polyomavirus (BKPyV) continues to threaten kidney transplantation outcomes by directly or indirectly causing premature allograft failure. Insufficient BKPyV-specific immunity underlies the onset and duration of BKPyV-DNAemia and nephropa...
Trypanosoma cruzi Retinitis Following Donor-Derived Chagas Disease After Heart Transplantation [0.03%]
一例心脏移植后捐献者传播的美洲幼虫病导致的眼底病变病例报告
Jessica A Kraker,Charlotte Mitchell,Nikita Saladi et al.
Jessica A Kraker et al.
Donor-derived Trypanosoma cruzi infection is a recognized complication of solid organ transplantation, but ocular involvement has never been reported. We described a case of necrotizing retinitis due to T. cruzi in a heart transplant recipi...
KSHV-Associated Diseases in Solid Organ Transplantation: Toward a Coordinated National Strategy in the United States [0.03%]
美国器官移植相关的卡波氏肉瘤病毒致病：迈向全国协调战略
Nazzarena Labo,Wendell Miley,Vickie Marshall et al.
Nazzarena Labo et al.
Although Kaposi sarcoma-associated herpesvirus (KSHV)-associated disease (KAD) has long been recognized as a complication of transplantation, in the past five years, the incidence of KAD among solid organ transplant recipients in the United...
Pretransplant Gut Microbiome Signatures Predict Early Acute Rejection After Kidney Transplantation [0.03%]
移植前肠道微生物组特征可预测肾移植后的早期急性排斥反应
Ji Eun Kim,Hyunjeong Cho,Jangwook Lee et al.
Ji Eun Kim et al.
Early identification of rejection remains a critical unmet need in kidney transplantation, as conventional tools detect rejection only after irreversible allograft injury. The pre-transplant gut microbiome may provide novel predictive signa...