Where you live matters: Area deprivation predicts poor survival and liver transplant waitlisting [0.03%]
你居住的地方很重要：地区剥夺预示着较差的生存率和肝脏移植等待列表
Bima J Hasjim,Alexander A Huang,Mitchell Paukner et al.
Bima J Hasjim et al.
Social determinants of health (SDOH) are important predictors of poor clinical outcomes in chronic diseases, but their associations among the general cirrhosis population and liver transplantation (LT) are limited. We conducted a retrospect...
Florent Artru,Mark J McPhail
Florent Artru
Acute-on-chronic liver failure is a well-established description of a high-mortality syndrome of chronic liver disease (usually cirrhosis) with organ failure. While the exact definition is under refinement, the accepted understanding of thi...
Donor-derived carbapenem-resistant gram-negative bacterial infections in solid organ transplant recipients: Active surveillance enhances recipient safety [0.03%]
实体器官移植受者中来自供者的碳青霉烯耐药阴性细菌感染：主动监控提高受者安全
Alessandra Mularoni,Andrea Cona,Maria Campanella et al.
Alessandra Mularoni et al.
Donor-derived infections (DDIs) caused by carbapenem-resistant gram-negative bacteria (CR-GNB) in solid organ transplant recipients are potentially life-threatening. In this prospective study, we evaluated the incidence, factors associated ...
The respiratory syncytial virus vaccines are here: Implications for solid organ transplantation [0.03%]
呼吸道合胞病毒疫苗对实体器官移植的影响现已显现
Paul Trubin,Marwan M Azar,Camille N Kotton
Paul Trubin
In 2023, the Food and Drug Administration approved 2 recombinant subunit respiratory syncytial virus (RSV) vaccines based on prefusion RSV F glycoproteins for the prevention of RSV-associated lower respiratory tract disease. These vaccines ...
Recurrence of membranous nephropathy after kidney transplantation: A multicenter retrospective cohort study [0.03%]
肾移植后膜性肾病的复发：一项多中心回顾性队列研究
Frank Hullekes,Audrey Uffing,Rucháma Verhoeff et al.
Frank Hullekes et al.
Membranous nephropathy (MN) is a leading cause of kidney failure worldwide and frequently recurs after transplant. Available data originated from small retrospective cohort studies or registry analyses; therefore, uncertainties remain on ri...
The decedent model: A new paradigm for de-risking high stakes clinical trials like xenotransplantation [0.03%]
死者模型：为高风险临床试验去风险化的全新范式——以异种移植为例
Robert A Montgomery,Adam D Griesemer,Dorry L Segev et al.
Robert A Montgomery et al.
The first 2 living recipients of pig hearts died unexpectedly within 2 months, despite both recipients receiving what over 30 years of nonhuman primate (NHP) research would suggest were the optimal gene edits and immunosuppression to ensure...
Neutralizing antibodies as key players in preventing BK polyomavirus replication: Insights from bench to bedside [0.03%]
中和抗体在预防BK多瘤病毒复制中的关键作用：从实验台到病床的启示
Ilies Benotmane,Sophie Caillard,Samira Fafi-Kremer et al.
Ilies Benotmane et al.
Genetic versus self-reported African ancestry of the recipient and neighborhood predictors of kidney transplantation outcomes in 2 multiethnic urban cohorts [0.03%]
受者基因和自我报告的非洲血统以及两个多民族城市队列中邻里预测因素对肾移植结果的影响
Francesca Zanoni,Y Dana Neugut,Joy E Obayemi et al.
Francesca Zanoni et al.
African American (AA) kidney recipients have a higher risk of allograft rejection and failure compared to non-AAs, but to what extent these outcomes are due to genetic versus environmental effects is currently unknown. Herein, we tested the...
Adjusting for race in metrics of organ procurement organization performance [0.03%]
器官采购组织绩效指标中种族调节因素
Jonathan M Miller,David Zaun,Nicholas L Wood et al.
Jonathan M Miller et al.
The Scientific Registry of Transplant Recipients has previously reported the effects of adjusting for demographic variables, including race, in the Centers for Medicare & Medicaid Services (CMS) organ procurement organization (OPO) performa...
Patient-centered research in pediatric transplant: Engaging families and recipients [0.03%]
以患者为中心的儿科移植研究：与家庭和接受者互动
Emily R Perito,Melissa McQueen,Jennifer Lau et al.
Emily R Perito et al.
Pediatric liver transplant (LT) recipients navigate a lifelong journey that includes constant monitoring and challenges. Research priorities and questions in LT have traditionally been provider-driven. This project was a novel partnership b...