Associations Between Donor-derived Cell-free DNA Dynamics and Clinical Outcomes After Kidney Allograft Rejection: A Prospective, Multi-center Study [0.03%]
肾移植排异后供体来源细胞游离DNA动态变化及其临床预后的相关性研究：一项前瞻性多中心研究
Suphamai Bunnapradist,Nicolae Leca,Ziad S Zaky et al.
Suphamai Bunnapradist et al.
Active rejection (AR) remains a major risk factor for graft dysfunction and loss. Donor-derived cell-free DNA (dd-cfDNA) is a dynamic, noninvasive biomarker for AR. We hypothesized that dd-cfDNA monitoring post-rejection may enable physicia...
Prevalence of major malformations and small for gestational age in newborns of female transplant recipients on tacrolimus-containing regimens during pregnancy [0.03%]
他克莫司在怀孕期间对新生婴儿大畸形和宫内发育迟缓的影响研究
Serban Constantinescu,Noah J Robinson,Michael W Marcus et al.
Serban Constantinescu et al.
In female transplant recipients, immunosuppressant use during pregnancy raises potential concerns about adverse maternal and fetal outcomes. This non-interventional study used prospectively- and retrospectively-reported cases from the Trans...
Location, location, location-How real estate immunity and preservation of self are defined [0.03%]
位置，位置，位置——房地产免疫和自我保护如何定义
Caitlin Drinkwater,Natasha M Rogers
Caitlin Drinkwater
Engaging Patients in Organ Transplant Listing Meetings: A Survey Study [0.03%]
一项关于器官移植列入名单会议的调查研究：动员患者参与
Aditya S Pawar,Nicole Scholes-Robertson,Kristen Kennefick et al.
Aditya S Pawar et al.
Organ transplant listing decisions are made by multidisciplinary selection committees using structured, deliberative processes to evaluate candidate eligibility. Engaging patients in these meetings has been proposed as a strategy to enhance...
By Lara C Pullen
By Lara C Pullen
Epigenetically modulating macrophage subpopulations to promote long-term allograft survival in a mouse heart transplant model [0.03%]
通过表观遗传调控小鼠心脏移植模型中巨噬细胞亚群促进长期移植物存活
Xiaojun Su,Ge Deng,Si Sun et al.
Xiaojun Su et al.
Despite much-improved protocols that broadly suppress the adaptive immune cells, most allografts are still lost to chronic rejection, in which macrophages have been prominently featured in the graft. In both clinical and pre-clinical studie...
Impact of kidney function on 200 days of antiviral prophylaxis for cytomegalovirus disease in CMV-seronegative recipients of CMV-seropositive donor kidneys Post hoc analysis of a randomized, phase 3 trial of letermovir versus valganciclovir prophylaxis [0.03%]
肾脏功能对CMV阴性受者接受阳性供体肾脏移植术后200天内预防CMV疾病的影响：Letermovir对比Valganciclovir的随机III期临床研究的事后分析
Klemens Budde,Nassim Kamar,Marta Crespo et al.
Klemens Budde et al.
This post-hoc analysis was conducted to understand the impact of kidney function on 200 days of cytomegalovirus (CMV) prophylaxis in CMV donor-positive/recipient-negative (D+R-) kidney transplant recipients (KTRs). Adult CMV D+R- KTRs were ...
Reply to Takefuji, Yoshiyasu - Beyond LASSO: A Comprehensive Framework for Analyzing Complex Biological Data Using Nonlinear and Nonparametric Methods [0.03%]
对武藤义康的回应——超越LASSO：使用非线性和非参数方法分析复杂生物数据的全面框架
Weiwei Ma,Ramsey R Hachem,Andrew P Michelson
Weiwei Ma
Letter to the Editor: Modernization Without Transparency: Our Decision to Resign from the OPTN Board [0.03%]
致编辑的信：缺乏透明度下的现代化：我们为何决定辞去OPTN董事会职务
Macey L Levan,Kelley Hitchman,Denise L Abbey et al.
Macey L Levan et al.
Cultural Myth vs. Systemic Failure: Why Japan's Deceased Organ Donation Rate Remains Stagnant [0.03%]
文化迷思与体制障碍：日本器官捐献为何停滞不前？
Keita Okubo,Kazunari Tanabe,Sumi Hidaka et al.
Keita Okubo et al.
Japan's organ donation rate remains among the lowest in the developed world, with only 4% of patients on the transplant waiting list receiving organs annually. While cultural explanations are often cited, this Viewpoint contends that struct...