Addressing vaccination coverage among pediatric solid organ transplant candidates and recipients in the post-COVID-19 pandemic period of increased vaccine hesitancy [0.03%]
后COVID-19大流行时期疫苗犹豫加剧背景下儿科实体器官移植供者和受者的疫苗接种覆盖率应对策略
Sanya J Thomas,Amy Feldman,Nicole Hayde et al.
Sanya J Thomas et al.
Pediatric solid organ transplant (PSOT) candidates and recipients remain under-vaccinated and at higher risk of vaccine preventable illness (VPI) than the general population. An American Society of Transplantation Pediatric Community of Pra...
Single cell transcriptional landscape of liver transplant rejection reveals tissue persistence of clonally expanded, treatment-resistant T cells [0.03%]
单细胞转录组图谱揭示肝移植排异反应中克隆扩增T细胞的组织驻留性及治疗抵抗性
Anna L Peters,Erica A K DePasquale,Gousia Begum et al.
Anna L Peters et al.
T cell mediated rejection (TCMR) affects ∼50% of pediatric liver transplant recipients within 5 years, and late TCMR is associated with graft failure due to ineffective treatment. Although CD8+ T cells promote late TCMR, their clonal expan...
Erythropoietin as a macrophage-specific immunoregulatory switch with implications for oncology and transplantation [0.03%]
促红细胞生成素作为巨噬细胞特异性免疫调节开关在肿瘤和移植中的潜在作用
Paolo Cravedi,James M Gardner
Paolo Cravedi
Machine perfusion for deceased donor kidney transplantation: network meta-analysis of the Cochrane review [0.03%]
尸体供者肾脏移植的机器灌注：Cochrane 系统评价的网状meta分析
Dharesh Raj Amarnath,Samuel J Tingle,Colin H Wilson
Dharesh Raj Amarnath
dd-cfDNA Significantly Improves Rejection Yield in Kidney Transplant Biopsies [0.03%]
dd-cfDNA显著提高肾移植活检的排斥反应产量
Jonathan S Bromberg,Daniel C Brennan,David J Taber et al.
Jonathan S Bromberg et al.
Donor-derived cell-free DNA (dd-cfDNA) is a biomarker that enables the early detection of immune-mediated graft injury. This study evaluated the clinical utility of dd-cfDNA in predicting the presence of biopsy-proven rejection (BPAR). We a...
Increase in New Delhi Metallo-β-Lactamase-Producing Carbapenem-Resistant Enterobacterales - New York City, 2019-2024 [0.03%]
2019-2024年纽约市新德里金属β-内酰胺酶产生碳青霉烯耐药肠杆菌科细菌增多
Marcus Pereira
Marcus Pereira
Pre-clinical research on the effect of thoraco-abdominal normothermic regional perfusion on pulmonary function: a comparison of two strategies [0.03%]
胸腹腔 normothermic 地区灌注对肺功能影响的临床前研究——两种策略的比较
Katrien Vandendriessche,Michaela Orlitová,Arno Vanstapel et al.
Katrien Vandendriessche et al.
Thoraco-abdominal normothermic regional perfusion (TA-NRP) is a novel technique to recover organs from donors after circulatory death by restoring regional circulation with extracorporeal support. However, its potential impact on pulmonary ...
Higher versus Standard Mean Arterial Pressure Target in the Immediate Postoperative Period of Liver Transplantation to Prevent Acute Kidney Injury: A Randomized Clinical Trial - (LIVER-PAM) [0.03%]
更高的平均动脉压目标值可以减少肝移植术后急性肾损伤：（肝脏-PAM）试验临床随机对照试验
Rodolpho Augusto de Moura Pedro,Bruna Carla Scharanch,Lucas de Oliveira Araújo et al.
Rodolpho Augusto de Moura Pedro et al.
Acute kidney injury (AKI) is a frequent complication after liver transplantation, with incidence up to 81%, and is associated with impaired long-term renal function, graft survival, and increased mortality. Hypotension is a modifiable risk ...
Antibodies to Angiotensin II Type 1 Receptor and Endothelin Type A Receptor are associated with Cytokine Production Enriched for Type 2 Immune Response and Antibody Production in Pediatric Kidney Transplant Recipients [0.03%]
儿童肾移植受者中血管紧张素II型1受体和内皮素A受体的自身抗体与富含第2种免疫反应及抗体产生的细胞因子产生相关
Meghan Pearl,Lucia Chen,Tristan Grogan et al.
Meghan Pearl et al.
Activating antibodies to angiotensin II type 1 receptor and endothelin type A receptor (AT1R and ETAR-Abs) have been associated with rejection, allograft loss, decline in allograft function, and development of HLA donor specific antibodies ...