miR-449a ameliorates acute rejection after liver transplantation via targeting procollagen-lysine1,2-oxoglutarate5-dioxygenase 1 in macrophages [0.03%]
mir-449a通过靶向巨噬细胞中的procollagen-lysine1,2-oxoglutarate5-dioxygenase 1改善肝移植后的急性排斥反应
Zhen-Rui Cao,Wei-Xiong Zheng,Yu-Xin Jiang et al.
Zhen-Rui Cao et al.
Acute rejection (AR) is an important factor that leads to poor prognosis after liver transplantation (LT). Macrophage M1-polarization is an important mechanism in AR development. MicroRNAs play vital roles in disease regulation; however, th...
The current state of transplant advanced practice providers: results of the advanced practice provider practice survey [0.03%]
移植高级执业提供者的现状:高级执业提供者实践调查的结果
Brenda L Muth,Danielle Krieger,Hazel Domingo et al.
Brenda L Muth et al.
Advanced practice providers (APPs) are trained, licensed health care providers. The American Society of Transplant APP community of practice developed an electronic survey to investigate transplant APP demographics, scope of practice, and a...
TIGIT agonism alleviates costimulation blockade-resistant rejection in a regulatory T cell-dependent manner [0.03%]
TIGIT 激动以调节性T细胞依赖性方式缓解共刺激阻断耐药排斥反应
Christina R Hartigan,Katherine P Tong,Danya Liu et al.
Christina R Hartigan et al.
Belatacept-based immunosuppression in kidney transplantation confers fewer off-target toxicities than calcineurin inhibitors but comes at a cost of increased incidence and severity of acute rejection, potentially due to its deleterious effe...
Infection and clinical xenotransplantation: Guidance from the Infectious Disease Community of Practice of the American Society of Transplantation [0.03%]
感染与临床异种移植:美国移植学会感染疾病实践社区的指导意见
Sapna A Mehta,Kapil K Saharia,Anoma Nellore et al.
Sapna A Mehta et al.
This guidance was developed to summarize current approaches to the potential transmission of swine-derived organisms to xenograft recipients, health care providers, or the public in clinical xenotransplantation. Limited specific data are av...
Donor and recipient human leukocyte antigen-G polymorphisms modulate the risk of adverse immunologic events following lung transplantation [0.03%]
供者和受者的HLA-G多态性可调节肺移植后免疫不良事件的发生率
Peter Riddell,Jin Ma,Julieta Lazarte et al.
Peter Riddell et al.
The long-term benefits of lung transplantation (LTx) are limited by pathogenic alloimmune responses that drive injury, inflammation, and chronic dysfunction. Human leukocyte antigen-G (HLA-G) plays a key role in the modulation of these path...
Darren Stewart,Tatenda Mupfudze,David Klassen
Darren Stewart
The median waiting time (MWT) to deceased donor kidney transplant is of interest to patients, clinicians, and the media but remains elusive due to both methodological and philosophical challenges. We used Organ Procurement and Transplantati...
A comparison of deprivation indices and application to transplant populations [0.03%]
剥夺指数的比较及其在移植人群中的应用
Christine Park,Tyler Schappe,Sarah Peskoe et al.
Christine Park et al.
The choice of deprivation index can influence conclusions drawn regarding the extent of deprivation within a community and the identification of the most deprived communities in the United States. This study aimed to determine the degree of...
Oxidative stress and related metabolic alterations are induced in ex situ perfusion of donated hearts regardless of the ventricular load or leukocyte depletion [0.03%]
无论心室负荷或白细胞耗竭,离体灌流的捐献心脏中都会诱导氧化应激和相关的代谢改变
Sanaz Hatami,Xiao Qi,Mobashir Khan et al.
Sanaz Hatami et al.
We sought to determine the role of donor blood circulating leukocytes in mediating oxidative stress and inflammation during normothermic ex situ heart perfusion (ESHP). Normothermic ESHP allows preservation of donated heart in a perfused, d...
American Society of Transplant Surgeons recommendations on best practices in donation after circulatory death organ procurement [0.03%]
美国移植外科医生协会关于循环死亡后器官获取最佳实践的建议
Kristopher P Croome,Andrew S Barbas,Bryan Whitson et al.
Kristopher P Croome et al.
The American Society of Transplant Surgeons supports efforts to increase the number of organs that are critically needed for patients desperately awaiting transplantation. In the United States, transplantation using organs procured from don...
Demographic and Clinical Characteristics of Mpox in Persons Who Had Previously Received 1 Dose of JYNNEOS Vaccine and in Unvaccinated Persons - 29 U.S. Jurisdictions, May 22-September 3, 2022 [0.03%]
接种一剂JYNNEOS疫苗者和未接种者中猴痘的流行病学和临床特征——来自美国29个管辖区的调查,2022年5月22日至9月3日
Jennifer L Farrar,Nathaniel M Lewis,Kennedy Houck et al.
Jennifer L Farrar et al.