High Glucose Supplementation Aggravates Experimental Autoimmune Epididymo-orchitis via Localized Th17 Skewing in the Male Reproductive Tract [0.03%]
高糖补充通过使雄性生殖道局部Th17偏移加重实验性自身免疫附睾炎-睾丸炎
Jin-Chuan Liu,Qun-Xiong Zeng,Fu Shi et al.
Jin-Chuan Liu et al.
Background: Chronic epididymo-orchitis contributes significantly to male infertility through immune cell infiltration and pro-inflammatory cytokine elevation. High glucose intake promotes Th17 differentiation and autoimmu...
Persistence of SARS-CoV-2 RNA Residues in Placenta Tissue Following Maternal COVID-19 Infection During Pregnancy [0.03%]
妊娠期感染COVID-19后胎盘组织中SARS-CoV-2 RNA残留的持续性
Yang Gu,Jie Xu,Xin Gu et al.
Yang Gu et al.
Problem: Prolonged SARS-CoV-2 viral persistence was reported in extrapulmonary tissues in patients infected with COVID-19. SARS-CoV-2 can infect placental tissue. However, little is known about SARS-CoV-2 viral persistenc...
Alterations in Cellular Immunity in Patients With Endometriosis: Systematic Review and Meta-Analysis [0.03%]
子宫内膜异位症患者的细胞免疫改变：系统评价和荟萃分析
Leila Adamyan,Laura Pivazyan,Kristina Kurbatova et al.
Leila Adamyan et al.
Determining the pathogenesis of endometriosis remains a major challenge in contemporary gynecology, and the investigation of alterations in cellular immunity may provide important insights into this issue. A comprehensive search of electron...
Altered Distribution of CD14+ Macrophages and Reduced ROS Activity in Preeclamptic Placentas [0.03%]
子痫前期胎盘CD14+巨噬细胞分布异常及反应氧簇活性降低
Luis Donis-Maturano,Judith Yenny Flores-Colque,Juana Calderon-Amador et al.
Luis Donis-Maturano et al.
Problem: Pregnancy requires a delicate balance between maternal immune tolerance and protective responses, with macrophages playing a pivotal role in placental development and immune regulation. Preeclampsia, a hypertensi...
EVT-Derived Migrasomes Provide Mechanistic Insights Into Antiphospholipid Syndrome-Associated Recurrent Miscarriage [0.03%]
基于EVT来源的迁移体从机制上解释了抗磷脂综合征相关的复发性流产
Di Wang,Yu Xie,Hongyuan Zhang et al.
Di Wang et al.
Objective: Recurrent miscarriage (RM) is a complex pregnancy-related disorder closely associated with impaired extravillous trophoblast (EVT). Antiphospholipid antibody syndrome (APS) is an autoimmune condition that contr...
First-Trimester Maternal CALLY Index Is Associated With Fetal Growth Restriction [0.03%]
妊娠早期母体CALLY指数与胎儿生长受限相关
Esra Karakus,Ali Furkan Yahsi,Kubra Katipoglu
Esra Karakus
Background: Fetal growth restriction (FGR) is a major cause of perinatal morbidity and is frequently associated with placental malperfusion related to inflammatory and immune dysregulation. This study evaluated whether th...
Evaluation of the Hemoglobin, Albumin, Lymphocyte, and Platelet Score and Inflammatory Markers in Preterm Premature Rupture of Membranes [0.03%]
评估胎膜早破的血红蛋白、白蛋白、淋巴细胞和血小板评分及炎症标志物
Çiğdem Akçabay,Dilara Duygulu Bulan,Batuhan Tepe et al.
Çiğdem Akçabay et al.
Problem: To evaluate the hemoglobin, albumin, lymphocyte, and platelet (HALP) score and its relationship with inflammatory markers in patients with preterm premature rupture of membranes (PPROM), and to assess their assoc...
Natural Products Targeting Oxidative Stress-Inflammation Crosstalk in Endometriosis [0.03%]
针对氧化应激-炎症相互作用的治疗子宫内膜异位症的天然药物
Divya Mhatre,Tanvi Jadhav,Sanket Shirodkar et al.
Divya Mhatre et al.
Problem: Endometriosis is a chronic, estrogen-dependent inflammatory disorder marked by ectopic endometrial-like tissue growth, resulting in pelvic pain, infertility, and significant declines in quality of life. Despite e...
Ferroptosis-Mediated Placental Dysfunction in the Pathophysiology of Gestational Diabetes Mellitus [0.03%]
铁死亡介导的胎盘功能障碍在妊娠糖尿病病理生理中的作用
S Monisha,K L Milan,M Anuradha et al.
S Monisha et al.
Problem: Gestational diabetes mellitus (GDM) is a common metabolic complication of pregnancy associated with adverse maternal and fetal outcomes. Nevertheless, the molecular mechanism of placental dysfunction in GDM are s...
The HIV Reservoir and Immune Landscape Across the Life Course of Women: Implications for Cure Strategies [0.03%]
女性生命周期中的HIV储存库和免疫景观：对治愈策略的意义
Elizabeth Hastie,Priya Khetan,Sarah A LaMere et al.
Elizabeth Hastie et al.
Sex hormones and reproductive transitions profoundly shape immune, metabolic, neuropsychological, and mucosal biology, as well as HIV persistence, across women's lives. Although women constitute the majority of people with HIV worldwide, ho...