Pilot Study Assessing the Efficacy of Melatonin and Osteogenic Loading on Bone Health in a Postmenopausal Population with Osteopenia: MelaOstrong Randomized Controlled Trial [0.03%]
评估褪黑激素和成骨负载对绝经后骨质疏松人群骨健康影响的试点研究：随机对照试验MelaOstrong
Afsana Jahan,Yong Myoung,Afsin Malik et al.
Afsana Jahan et al.
The purpose of this 1-year study was to assess the effect of osteogenic loading combined with melatonin on musculoskeletal health and well-being in a population with osteopenia. Participants were randomized into one of four groups and recei...
Randomized Controlled Trial
Journal of pineal research. 2025 Nov;77(6):e70088. DOI:10.1111/jpi.70088 2025
The Mechanism by Which Melatonin Improves the Dysregulation of Glucose and Lipid Metabolism in Castrated Female Mice [0.03%]
褪黑素改善去势大鼠糖脂代谢紊乱的机制研究
Xin Jin,Xuan Liu,Yunjuan Wang et al.
Xin Jin et al.
Postmenopausal women have a significantly increased risk of cardiovascular disease and osteoporosis due to the lack of estrogen protection. To explore the effects of melatonin on clock genes and glucose and lipid metabolic disorders of post...
Melatonin-Producing Microorganisms: A Rising Research Interest in Their Melatonin Biosynthesis and Effects on Crops [0.03%]
产褪黑素微生物：它们的褪黑素生物合成及对农作物的影响研究日益增多
Sang-Mo Kang,Ashim Kumar Das,Da-Sol Lee et al.
Sang-Mo Kang et al.
Melatonin is imperative in animals and plants, contributing to multiple physiological roles, and its microbial production could offer an eco-friendly alternative to synthetic melatonin. However, detecting and characterizing it in microorgan...
Circadian Misalignment as a Determinant of Insomnia Severity: Possible Implications in Sleep Medicine Clinical Practice [0.03%]
昼夜节律失调与失眠严重程度的关系及其在睡眠医学临床实践中的意义
Alessandro Colitta,Ugo Faraguna
Alessandro Colitta
In this letter to the editor, we comment on the recently published study from Scott et al. (2025), which highlights circadian misalignment as a possible determinant of insomnia severity. Considering the robust methodology of this study and ...
Relationship Between Urinary 6-Sulfatoxymelatonin Rhythms and the Bone Resorption Marker Amino-Terminal Cross-Linked Telopeptide of Collagen I in Blind Women [0.03%]
盲人女性尿液6-硫酸水杨胺节律与骨吸收标志物I型胶原交联N末端肽关系研究
Melissa A St Hilaire,Erin E Flynn-Evans,Shadab A Rahman et al.
Melissa A St Hilaire et al.
Evidence exists for the daily rhythmicity of bone metabolism that may be influenced by melatonin production, reproductive hormones, the light/dark cycle, or all three, but the ability to determine their independent contributions is confound...
Sequence Symmetry Analysis of the Interrelationships Between Ramelteon and Parkinson's Disease [0.03%]
瑞美隆与帕金森病之间互作关系的序列对称性分析
Yoshihiro Noguchi,Rikuto Masuda,Tomoaki Yoshimura
Yoshihiro Noguchi
Parkinson's disease is the second most frequent neurodegenerative disease after Alzheimer's disease, and the most common neurodegenerative disease that causes movement dysfunction. Without innovations in prevention and treatment, the incide...
Melatonin Ameliorates Circadian Disruption-Associated Dry Eye via Modulation of BMAL1-REV-ERBα-IL-17 Axis and Ocular Surface Microbiota Homeostasis [0.03%]
褪黑素通过调节BMAL1-REV-ERBα-IL-17轴和眼表微生物群稳态来改善昼夜节律紊乱相关干眼病
Bowen Wang,Hao Zeng,Xue Yang et al.
Bowen Wang et al.
The association between modern lifestyle factors and dry eye disease (DED) pathogenesis has garnered increasing scientific attention. Emerging evidence implicates circadian disruption-a prevalent consequence of contemporary living patterns-...
Melatonin Boosts the Phytochemical Profile of Blood Oranges, Enhancing (Poly)phenol and Endogenous Melatonin Content, Through Pre- and Postharvest Treatments [0.03%]
褪黑素通过预处理和后收获处理提升血橙的植物化学特性，增强（ poly）酚和内源性褪黑素含量
Fernando Garrido-Auñón,Pedro Antonio Padilla-González,María Serrano et al.
Fernando Garrido-Auñón et al.
Nowadays, increasing consumer awareness of the link between diet and health has underscored the value of bioactive compounds in preventing metabolic disorders. In this frame, blood oranges are highly appreciated for their unique phytochemic...