Panax notoginseng Saponins Alleviate OSF by Inhibiting Ferroptosis Through GPX4 Activation [0.03%]
三七总皂苷通过激活GPX4抑制铁死亡从而改善口腔粘膜放射损伤
Xinyue Zhang,Yujie Sun,Chenxi Zhao et al.
Xinyue Zhang et al.
Objectives: Oral submucous fibrosis (OSF) is a chronic progressive disease characterized by fibrosis. Panax notoginseng saponins (PNS) are effective components of the traditional Chinese medicine Panax notoginseng and pla...
Chemerin, OPG, and WPOI as Markers of Bone Invasion and Prognosis in Oral Squamous Cell Carcinoma [0.03%]
化学引诱素、OPG和WPOI在口腔鳞癌骨侵袭及预后中的标志物作用
Jonas Eichberger,Juliane Schmelzer,Michael Gerken et al.
Jonas Eichberger et al.
Background: The objective of our study was to examine the role of Chemerin, Chemokine like receptor 1 (CMKLR1), receptor activator of nuclear factor kappa-Β ligand (RANKL), and Osteoprotegerin (OPG) in the development of...
Clinical Features Associated With Malignant Transformation of Low-Grade Dysplasia [0.03%]
低级别上皮内瘤变恶变的临床特征分析
Denise M Laronde,Matt Berkowitz,A Ross Kerr et al.
Denise M Laronde et al.
Background: Inferring risk for malignant transformation (MT) in patients with lesions diagnosed as mild or moderate oral epithelial dysplasia (low-grade OED) remains challenging. We developed two models assessing the risk...
Sue-Ching Yeoh,Stephen Adelstein,Omar Kujan
Sue-Ching Yeoh
Background: Pemphigus vulgaris is a rare autoimmune blistering condition characterised by mucocutaneous lesions secondary to acantholysis. Assessment of disease activity, severity, and treatment response is crucial for gu...
Clinicopathological Profile of Intraosseous Adenoid Cystic Carcinoma of the Jaws: A Systematic Review [0.03%]
关于颌骨牙腺样囊性癌的临床病理特征：系统回顾
Luccas Lavareze,João Figueira Scarini,Reydson Alcides de Lima-Souza et al.
Luccas Lavareze et al.
Objectives: We aimed to evaluate the clinicopathological features, survival rate, and potential prognostic markers of the jaws' primary intraosseous adenoid cystic carcinoma (PIACC). ...
Elevated N6-Methyladenosine (m6A)-RNA-Methylation During Oral Carcinogenesis [0.03%]
口腔癌变过程中N6-甲基腺苷(m6A) RNA甲基化水平升高
Zhiming Qin,Yanting Chi,Xinpei Wang et al.
Zhiming Qin et al.
Background/purpose: Oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC) encompass a series of molecular events in the malignant transformation process, ranging from simple epithelial hyperplasia to mil...
Chukwuemeka L Anyikwa,Peter A Brennan,Chukwuebuka E Ogwo
Chukwuemeka L Anyikwa
Oral diseases affect billions worldwide yet remain sidelined in both national and global health policies. This oversight has perpetuated disparities in care access, particularly in low- and middle-income countries. The separation of oral he...
Dental Pulp Mesenchymal Stem Cell-Secretome Gel Reverse Areca Nut Induced Oral Submucous Fibrosis in Mice: A Pilot Study [0.03%]
牙髓间充质干细胞分泌组凝胶逆转.areca nut.诱导的小鼠口腔粘膜下纤维化：一项初步研究
Nishant Mante,Supriya Kheur,Avinash Sanap et al.
Nishant Mante et al.
Objectives: Oral submucous fibrosis is a pre-malignant disorder caused by habitual areca nut consumption. This pilot study investigated the therapeutic potential of dental pulp mesenchymal stem cell-secretome chitosan gel...
Prevalence of Oral Alterations and Correlation Between Oral and Cutaneous Neurofibromas in Neurofibromatosis Type 1: A Retrospective Case-Control Study [0.03%]
I型神经纤维瘤病口腔病变的患病率及其与皮肤神经纤维瘤相关性的病例对照研究
Pâmella de Pinho Montovani,Gabriela Pizão Werneck Moreira da Costa,Rafaela Elvira Rozza-de-Menezes et al.
Pâmella de Pinho Montovani et al.
Objective: The aim of this study was to determine the prevalence of oral alterations detectable through physical examination in NF1 individuals. Additionally, we assessed the correlation between the number of oral and cut...
The PI3K Inhibitor HCD Promotes Caspase Activation in Head and Neck Squamous Cells by Upregulating the Extrinsic and Intrinsic Apoptosis Pathways [0.03%]
PI3K抑制剂HCD通过上调头颈部鳞状细胞的外在和内在凋亡途径促进半胱天冬酶活化
Leong-Perng Chan,Ya-Ping Tseng,Hui-Ching Wang et al.
Leong-Perng Chan et al.
Background: 16-hydroxycleroda-3,13-dien-15,16-olide (HCD), a compound isolated from Polyalthia longifolia var. pendula, has been identified as a PI3K inhibitor. P. longifolia var. pendula is recognized for its diverse pha...