Early-Onset Oral Squamous Cell Carcinoma: Emerging Biological Insights, Risk Factors and Clinical Implications [0.03%]
Gennaro Musella,Cristina D&#x;Antonio,Federica Canfora et al.
Gennaro Musella et al.
Background: Early-onset oral squamous cell carcinoma (EO-OSCC), commonly defined as occurring in individuals under 50 years of age, is increasingly recognized as a potentially distinct clinical subset with differences in ...
Immunological Biomarkers in Oral Leukoplakia According to Oral Intraepithelial Neoplasia (OIN) Classification: A Comparative Analysis of Salivary and Plasma Cytokines [0.03%]
根据口腔原位瘤(OIN)分类的口腔黏膜白斑免疫生物标志物：唾液和血浆细胞因子比较分析
Hakan Yülek,Gaye Keser,Başak Aru et al.
Hakan Yülek et al.
Background: Oral leukoplakia (OL) is the most common oral potentially malignant disorder, defined as a white patch or plaque not attributable to other causes. While OL carries an inherent risk of malignant transformation,...
Sclerosing Odontogenic Carcinoma: A Review of a Challenging Entity in Malignant Odontogenic Classification With a Focus on Perineural Invasion and Cellular Proliferation [0.03%]
硬化性成釉细胞瘤癌：恶性成釉瘤分类中一个具有挑战性的实体的回顾，重点是神经周围浸润和细胞增殖
Merva Soluk-Tekkesin,Keith David Hunter,Ronell Bologna-Molina et al.
Merva Soluk-Tekkesin et al.
Background: Sclerosing odontogenic carcinoma (SOC) is a rare intraosseous neoplasm defined by the World Health Organization as a locally aggressive tumor with "no metastatic potential". ...
Mucosal Melanoma of Head and Neck: A Rare and Aggressive Disease-A Register-Based Cohort Study [0.03%]
头颈部黏膜黑色素瘤：一种罕见且具有侵袭性的疾病-基于登记的队列研究
Sara C Degerholm,Tuula A Salo,Matti O Mauramo
Sara C Degerholm
Background: Mucosal melanomas of the head and neck are rare and often diagnosed in the advanced stage. This study examines the incidence, survival and histology of mucosal melanoma compared to its cutaneous counterpart. ...
p16 and MGMT Methylation in Chronic Traumatic Ulcers: A Plausible Link Between Chronic Mechanical Irritation and Oral Carcinogenesis? [0.03%]
P16和MGMT甲基化在慢性创伤性溃疡中的作用：慢性机械刺激与口腔癌变之间的可能联系？
Jeronimo Pablo Lazos,Marcela Hernandez Rios,Jessica Astorga et al.
Jeronimo Pablo Lazos et al.
Background: Chronic mechanical irritation (CMI) has been proposed as a risk factor for oral cancer. Epigenetic alterations, particularly methylation, are early events in carcinogenesis, and it has been proposed that they ...
Epithelial-Mesenchymal Transition, Immune Response, and Extracellular Matrix Remodelling in Oral Cancer [0.03%]
口腔癌上皮间质转化、免疫反应及细胞外基质重塑
Nicole Lonni,Camilla Kammer Pereira,Amanda Maciel Costa et al.
Nicole Lonni et al.
Aim: This retrospective study investigates the interplay between epithelial-mesenchymal transition (EMT) and immune response within the tumor microenvironment (TME) of oral squamous cell carcinoma (OSCC). ...
Vitamin D Modulates Doxorubicin-Induced ACE2 Expression and Pro-Inflammatory Cytokines in the Rat Tongue [0.03%]
维生素D调节阿霉素诱导的大鼠舌组织ACE2表达及促炎因子释放
Mustafa Sami Demirsoy,Aras Erdil,Sefa Çolak et al.
Mustafa Sami Demirsoy et al.
Purpose: Doxorubicin (DOX) is a widely used chemotherapy drug, but its severe toxic effects, including inflammation and taste disturbances, limit its clinical use. This study examined the protective effects of vitamin D o...
Mousa Ali Heba,Resteu Anastasia,Werner Andreas et al.
Mousa Ali Heba et al.
Background: Oral lichen planus (OLP) is a chronic T-cell-mediated immune disease of unknown aetiology. MicroRNA (miRNAs) are short non-coding RNAs capable of regulating mRNA and may have roles in T-cell-related diseases. ...
Association of p16INK4A Methylation With Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders: A Systematic Review and Meta-Analysis [0.03%]
p16INK4A甲基化与口腔鳞状细胞癌和口腔潜在恶性疾病的关系：系统评价和 meta 分析
Rairam Fernandes de Aguiar,Denis Francisco Gonçalves de Oliveira,Lucas Moreira de Araújo et al.
Rairam Fernandes de Aguiar et al.
Introduction: Methylation of tumor-suppressor gene promoters, particularly p16INK4A, is implicated in oral carcinogenesis. Although associations with oral squamous cell carcinoma (OSCC) and oral potentially malignant diso...
Sjögren's Disease and Cancer: Key Predictors From the Spanish Multicenter SjögrenSER-TRANS Cohort [0.03%]
西班牙多中心SjögrenSER-TRANS队列中的舍格伦病与癌症：关键预测因素
Olga Rusinovich-Lovgach,Zulema Plaza,Mónica Fernández Castro et al.
Olga Rusinovich-Lovgach et al.
Objective: To identify key clinical and therapeutic predictors of malignancy in a well-characterized, multicenter Spanish cohort of patients with Sjögren's disease (SjD). ...