Novel SOS1 Mutations Associated With Hereditary Gingival Fibromatosis and Dual-Gated Model for SOS1 Activation [0.03%]
与遗传性牙龈纤维瘤病相关的新型SOS1突变和SOS1激活的双门控模型
Qian Gao,Chengcan Yang,Nuo Xu et al.
Qian Gao et al.
Background: Hereditary gingival fibromatosis (HGF) is a rare, genetically heterogeneous disorder characterized by benign, slowly progressive fibrous overgrowth of the gingiva. This study aimed to identify the pathogenic g...
TGF-β1 Up-Regulates PLAU Expression to Promote Invasion and Migration of Oral Squamous Cell Carcinoma [0.03%]
TGF-β1通过上调PLAU表达促进口腔鳞癌侵袭和迁移
Gaoren Lin,Honglan Wang,Dandan Zhang et al.
Gaoren Lin et al.
Introduction: Dysregulated expression of urokinase-type plasminogen activator (PLAU), a serine protease, is frequently associated with various cancers. However, in oral squamous cell carcinoma (OSCC), the specific biologi...
Oral Dysesthesia and Mandibular Dyskinesia as First Signs and Symptoms of Primary Familial Brain Calcification (PFBC) Associated With a Novel Splice Site Mutation in the SLC20A2 Gene [0.03%]
与SLC20A2基因新型剪接位点突变相关的原发性家族性脑钙化(PFBC)的首发症状为口腔部烧灼感和下颌不自主运动
Laura Sisalli,Mario Caggiano,Massimo Amato et al.
Laura Sisalli et al.
Comparative Pilot Study of Chronic Hyperplastic Candidiasis and Atypical Epithelial Proliferation With Candida Utilizing p53, p16, CD44, and OCT4 Immunohistochemistry [0.03%]
利用p53、p16、CD44和OCT4免疫组化比较慢性增生性念珠菌病与非典型上皮增生中的念珠菌
Jessica Li,Indraneel Bhattacharyya,Sumita Sam et al.
Jessica Li et al.
Introduction: Chronic hyperplastic candidiasis (CHC) has a controversial potential role in the carcinogenesis of oral epithelium. In addition, histological overlap between CHC and atypical epithelial proliferation with Ca...
Diagnostic Performance of the PrevoCheck for the Detection of Human Papillomavirus 16-Driven Head and Neck Squamous Cell Carcinoma [0.03%]
Prevocheck检测人乳头瘤病毒16型驱动的头颈鳞癌的诊断性能
Charlotte S Schouten,Vittoria Guarda,Thomas M Stadler et al.
Charlotte S Schouten et al.
Background: Human papillomavirus (HPV)-16 is the most commonly found HPV-type in HPV-induced oropharyngeal squamous cell carcinomas (OPSCC). The serological response to HPV oncoproteins could be a way to detect HPV-driven...
Prediction of Extranodal Extension in Oral Squamous Cell Carcinoma Using Demographic and Clinicopathological Variables-Evidence From a Multicentre Study [0.03%]
基于多中心研究证据利用人口统计学和临床病理变量预测口腔鳞状细胞癌的淋巴结外侵犯
Thomas George Kallarakkal,B S M S Siriwardena,Ariyapala Samaranayaka et al.
Thomas George Kallarakkal et al.
Background: Cervical lymph node metastasis is one of the most important prognosticators in oral squamous cell carcinoma (OSCC). The presence of extranodal extension (ENE) in metastatic nodes further worsens the prognosis....
Characteristics of Acyclovir-Resistant Herpes Simplex Virus Infection in Hematological Patients [0.03%]
血液病患者抗病毒治疗失败的难治性HSV感染的临床特点及发病机制分析
Reema Shehadeh,Mor Bar Ilan,Sara Dovrat et al.
Reema Shehadeh et al.
Objective: Acyclovir-resistant herpes simplex virus infections pose a significant challenge in immunosuppressed patients. This study aimed to characterize the clinical features, treatment outcomes, and mortality associate...
Predicting Malignant Transformation in Oral Leukoplakia: A Multilayer Perceptron Approach Incorporating Clinicopathological Features and DNA Content [0.03%]
结合临床病理特征和DNA含量的多层感知器方法在口腔白斑恶性转化预测中的应用研究
Guilherme Iani Pontes,Anna Luíza Damaceno Araújo,Andresa Borges Soares et al.
Guilherme Iani Pontes et al.
Background: Oral leukoplakia (OL) is a potentially malignant disorder of the oral mucosa. Accurate prediction of malignant transformation (MT) remains a clinical challenge. This study aimed to develop and evaluate a machi...
Thiago Guedes Pinto,Wilton Mitsunari Takeshita,Patricia Ramos Cury et al.
Thiago Guedes Pinto et al.
Jujuboside A Alleviates Facial Allodynia of CCI-ION Rats by Inhibiting the Expression of P2X7 Receptor in the Spinal Trigeminal Subnucleus Caudalis [0.03%]
柚皮苷A通过抑制三叉神经脊束核尾端P2X7受体表达缓解CCI-ION大鼠面部痛觉过敏
Min Zhou,Wei Han,Yangyuan Wu et al.
Min Zhou et al.
Background: Trigeminal neuralgia is a common neuropathic pain of the oral and maxillofacial region. P2X7 receptor, a neural mediator, P2X7 receptor is closely related to this condition. Despite several studies on the role...