The impact of infections on the onset of contrast-associated acute kidney injury in patients with cirrhosis [0.03%]
感染对肝硬化患者对比剂相关急性肾损伤的发生的影响
Tammo L Tergast,Benjamin Maasoumy
Tammo L Tergast
A beneficial response of fetal wound healing gone bad in the bile duct: The overarching cause of biliary atresia? [0.03%]
胎儿伤口愈合的有益反应在胆管中变坏：这是胆道闭锁的主要原因？
David C Trampert,Ulrich Beuers
David C Trampert
Ileitis promotes MASLD progression via bile acid modulation and enhanced TGR5 signaling in ileal CD8+ T cells [0.03%]
回肠炎通过调节胆酸和增强回肠CD8+ T细胞中的TGR5信号来促进MASLD的发展
Chang Zheng,Lei Wang,Tianhui Zou et al.
Chang Zheng et al.
Background & aims: Clinical evidence substantiates a link between inflammatory bowel disease, particularly Crohn's disease (CD), and metabolic dysfunction-associated steatotic liver disease (MASLD). This study aims to exp...
IL-10 dampens antitumor immunity and promotes liver metastasis via PD-L1 induction [0.03%]
通过诱导PD-L1的表达，IL-10抑制抗肿瘤免疫并促进肝转移的发生
Ahmad Mustafa Shiri,Tao Zhang,Tanja Bedke et al.
Ahmad Mustafa Shiri et al.
Background & aims: The liver is one of the organs most commonly affected by metastasis. The presence of liver metastases has been reported to be responsible for an immunosuppressive microenvironment and diminished immunot...
Hepatic encephalopathy and survival after transjugular intrahepatic portosystemic shunt: Do spontaneous portosystemic shunts matter? [0.03%]
经颈静脉肝内门体分流术后肝性脑病与生存率：自发的门体分流有关系吗？
Feng Zhang,Ming Zhang,Lei Wang et al.
Feng Zhang et al.
Efficient formation and maintenance of humoral and CD4 T-cell immunity targeting the viral capsid in acute-resolving hepatitis E infection [0.03%]
急性自限性戊型肝炎感染中针对病毒衣壳体液免疫和CD4 T细胞免疫的高效形成与维持
Benedikt Csernalabics,Mircea Stefan Marinescu,Lars Maurer et al.
Benedikt Csernalabics et al.
Background & aims: CD4 T cells shape the neutralizing antibody (nAb) response and facilitate viral clearance in various infections. Knowledge of their phenotype, specificity and dynamics in hepatitis E virus (HEV) infecti...
Reply to: "Incorporating AFP-L3 and DCP in selecting patients with hepatocellular carcinoma for liver transplantation: What are the optimal criteria?" [0.03%]
《在选择肝细胞癌患者进行肝脏移植中纳入AFP-L3和DCP：最优标准是什么？》回复
Joshua S Norman,Neil Mehta
Joshua S Norman
Safety and efficacy of the oral TLR8 agonist selgantolimod in individuals with chronic hepatitis B under viral suppression [0.03%]
口服TLR8激动剂selgantolimod在病毒抑制的慢性乙型肝炎个体中的安全性和有效性研究
Edward J Gane,P Rod Dunbar,Anna E Brooks et al.
Edward J Gane et al.
Background & aims: Selgantolimod (GS-9688) is a Toll-like receptor 8 (TLR8) agonist that suppresses HBV in vitro. In a phase II study, we evaluated the safety and efficacy of weekly selgantolimod treatment in virally supp...
Clinical Trial
Journal of hepatology. 2023 Mar;78(3):513-523. DOI:10.1016/j.jhep.2022.09.027 2023
Tailoring allocation policies and improving access to paediatric liver transplantation over a 16-year period [0.03%]
长达16年儿童肝移植分配政策的调整和改善患儿获取移植肝脏的机会
Marco Spada,Roberta Angelico,Silvia Trapani et al.
Marco Spada et al.
Background & aims: Mortality on the paediatric liver transplantation (pLT) waiting list (WL) is still an issue. We analysed the Italian pLT WL to evaluate the intention-to-treat (ITT) success rate and to identify factors ...
Adipose tissue macrophage dysfunction in human MASLD - Cause or consequence? [0.03%]
人类MASLD患者脂肪组织巨噬细胞功能障碍是病因还是结果？
Fabio Colella,Prakash Ramachandran
Fabio Colella