Non-selective β-blockers reduce bacterial translocation by restoring gut barrier function during experimental cirrhosis [0.03%]
非选择性β受体阻滞药通过恢复实验性肝硬化时的肠道屏障功能来减少细菌移位
Elisa Castillo,Marco Felber,Lorena Paule et al.
Elisa Castillo et al.
Background & aims: Intestinal barriers limiting gut-to-liver translocation of bacteria/l products are disrupted in cirrhosis. Cirrhosis is characterised by sustained β-adrenergic overactivity, which may contribute to bar...
Corrigendum to "Development and validation of the A-TANGO organ failure score for acute-on-chronic liver failure in global cohorts" [J Hepatol 85 (2026) 91-105] [0.03%]
“急性-on-慢性肝功能衰竭的A-TANGO器官功能评分在不同地区的开发和验证”的勘误表
Cornelius Engelmann,Nipun Verma,Tingting Qi et al.
Cornelius Engelmann et al.
Published Erratum
Journal of hepatology. 2026 Jul 25:S0168-8278(26)02713-3. DOI:10.1016/j.jhep.2026.07.005 2026
The hepatocellular carcinoma wish list: Five aspirations for future care [0.03%]
肝癌诊疗展望：未来五年的发展方向与期望成果
Stephen L Chan,Bruno Sangro,Lorenza Rimassa
Stephen L Chan
A framework and shared vocabulary to identify actionable protein biomarkers and enable optimal precision medicine: Myth-Busting with Unicorn Biomarkers [0.03%]
一种识别可操作的蛋白质生物标志物和实现最佳精准医疗的框架和共享词汇：用独角兽生物标志物破除迷思
Morten A Karsdal,Anne-Christine Bay-Jensen,Daniel Guldager Kring Rasmussen et al.
Morten A Karsdal et al.
Not all biomarkers are equal, and some should not be termed biomarkers. Despite an explosion in putative biomarker discoveries from high-throughput proteomic technologies, very few advance beyond initial excitement to become validated, clin...
An ABC approach for preoperative staging in perihilar cholangiocarcinoma An international multicenter cohort study [0.03%]
一种肝门胆管癌术前分期的ABC方案：国际多中心队列研究
Britte H E A Ten Haaft,Alessandro M Bonomi,Bas Groot Koerkamp et al.
Britte H E A Ten Haaft et al.
Background & aims: Curative-intent surgery in patients with perihilar cholangiocarcinoma (pCCA) is associated with substantial surgical risks and high early-recurrence rates. This study aimed to develop an ABC system for ...
IL-19 limits macrophage-driven inflammation in acetaminophen-induced liver injury [0.03%]
白细胞介素19通过限制乙酰氨基酚致肝损伤中的巨噬细胞驱动炎症而发挥作用
Dongwei Jia,Yasuko Iwakiri
Dongwei Jia
Alastair D Burt,Cynthia Behling,Annette S H Gouw et al.
Alastair D Burt et al.
Numerous observations have indicated that significant amounts of liver fibrosis can either completely disappear or be substantially remodelled following removal of the initiating agent or with therapeutic intervention. Reversal of establish...
Gonzalo Sapisochin,Grainne M O&#x;Kane,Anudari Zorigtbaatar et al.
Gonzalo Sapisochin et al.
Surgical resection is a cornerstone of curative therapy for hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA), the two most common primary liver malignancies. In most patients with HCC, underlying cirrhosis is presen...
Redefining healthy human liver zonation using high-resolution spatial multiomics [0.03%]
基于高通量空间多组学技术重塑健康人肝功能区划分标准
Prakash Ramachandran
Prakash Ramachandran
Disruption of carbon metabolism by the hepatic mononuclear phagocytic system drives liver injury in a mouse model of severe dengue [0.03%]
小鼠登革热重症模型中的肝单核吞噬系统扰乱碳代谢致肝损伤
Qian Chen,Wei Yang,Yi-Zhen Yuan et al.
Qian Chen et al.
Background & aims: Severe dengue (SD) is the leading cause of morbidity and mortality resulting from dengue virus (DENV) infection, with liver injury being one of the most common complications. However, besides symptomati...