Lucy Meunier,Eleonora De Martin;REFHEPS group
Lucy Meunier
Wajahat Z Mehal
Wajahat Z Mehal
Molecular force-induced liberation of transforming growth factor-beta remodels the spleen for ectopic liver regeneration [0.03%]
分子力诱导转化生长因子-β释放重塑脾脏以实现异位肝脏再生
Zhenzhen Wang,Daping Xie,Jiayi Li et al.
Zhenzhen Wang et al.
Background & aims: Ectopic liver regeneration in the spleen is a promising alternative to organ transplantation for treating liver failure. To accommodate transplanted liver cells, the splenic tissue must undergo structur...
A novel treatment strategy utilizing panobinostat for high-risk and treatment-refractory hepatoblastoma [0.03%]
利用泛脱乙酰酶抑制剂治疗高风险及难治性肝母细胞瘤的新策略
Andres F Espinoza,Roma H Patel,Kalyani R Patel et al.
Andres F Espinoza et al.
Background & aims: Patients with metastatic, treatment-refractory, and relapsed hepatoblastoma (HB) have survival rates of less than 50% due to limited treatment options. To develop new therapeutic strategies for these pa...
Radiotherapy following intrahepatic progression on immunotherapy in advanced hepatocellular carcinoma [0.03%]
晚期肝细胞癌免疫治疗过程中发生肝内进展后接受放射治疗
Landon L Chan,Kevin Mok,Stephen L Chan
Landon L Chan
Optimal hepatitis C treatment adherence patterns and sustained virologic response among people who inject drugs: The HERO study [0.03%]
注射毒品者中丙型肝炎治疗依从性模式与持续病毒学反应的最佳化：HERO研究
Moonseong Heo,Brianna L Norton,Irene Pericot-Valverde et al.
Moonseong Heo et al.
Background & aims: Direct-acting antivirals (DAAs) are highly effective for treating HCV infection even among people who inject drugs (PWID). Yet, little is known about patients' adherence patterns and their association w...
BMI status and its changes across adulthood in relation to all-cause mortality in metabolic dysfunction-associated steatotic liver disease [0.03%]
与代谢功能障碍相关性肝病成年期全程的体重指数及其变化对全因死亡率的影响关系研究
Zhen Sun,Mengsi Liu,Jianglong Guo et al.
Zhen Sun et al.
Loreta A Kondili,Jeffrey V Lazarus,Peter Jepsen et al.
Loreta A Kondili et al.
Given the increasing burden of liver cancer in Europe, it is crucial to investigate how social determinants of health (SDoH) affect liver cancer risk factors and access to care in order to improve health outcomes equitably. This paper summa...
TRIB3-TRIM8 complex drives NAFLD progression by regulating HNF4α stability [0.03%]
TRIB3-TRIM8复合物通过调节HNF4α的稳定性驱动NAFLD进展
Meng-Chao Xiao,Nan Jiang,Li-Lin Chen et al.
Meng-Chao Xiao et al.
Background & aims: Endoplasmic reticulum (ER) stress of hepatocytes plays a causative role in non-alcoholic fatty liver disease (NAFLD). Reduced expression of hepatic nuclear factor 4α (HNF4α) is a critical event in the...
Sho Osonoi,Takanori Takebe
Sho Osonoi
Metabolic dysfunction-associated steatotic liver disease affects millions of people worldwide. Progress towards a definitive cure has been incremental and treatment is currently limited to lifestyle modification. Hepatocyte-specific lipid a...