Reply to: "Patients with hepatocellular carcinoma and portal vein tumour thrombosis after successful downstaging may be candidates for liver transplantation: A meta-analysis" [0.03%]
成功降期后肝细胞癌合并门静脉肿瘤血栓的患者可能适合进行肝脏移植:一项荟萃分析回复
Arvinder Soin,Mickael Lesurtel,Pierre A Clavien
Arvinder Soin
Researchers call for more flexible editorial conduct rather than abruptly adopting only the new MASLD nomenclature [0.03%]
研究人员呼吁采用更加灵活的编辑规范,而不是突然仅采用新的MASLD命名法
Amedeo Lonardo,Fernando Bril,Stephen H Caldwell et al.
Amedeo Lonardo et al.
Therapeutic vaccine-induced plasma cell differentiation is defective in the presence of persistently high HBsAg levels [0.03%]
治疗性疫苗诱导的浆细胞分化在持续高HBsAg水平存在时缺陷
Ruoyao Qi,Rao Fu,Xing Lei et al.
Ruoyao Qi et al.
Background & aims: Mechanisms behind the impaired response of antigen-specific B cells to therapeutic vaccination in chronic hepatitis B virus (HBV) infection remain unclear. The development of vaccines or strategies to o...
Major HBV splice variant encoding a novel protein important for infection [0.03%]
编码新型感染重要蛋白的主要HBV剪切变异体
Chen-Yen Chung,Cheng-Pu Sun,Mi-Hua Tao et al.
Chen-Yen Chung et al.
Background & aims: HBV expresses more than 10 spliced RNAs from the viral pregenomic RNA, but their functions remain elusive and controversial. To address the function of HBV spliced RNAs, we generated splicing-deficient ...
Sex-determining region Y gene promotes liver fibrosis and accounts for sexual dimorphism in its pathophysiology [0.03%]
SRY基因促进肝纤维化及其病理生理过程中的性别差异现象
Xiao-Ning Wu,Meng-Zhou Wang,Nan Zhang et al.
Xiao-Ning Wu et al.
Background & aims: Men are more prone to develop and die from liver fibrosis than women. In this study, we aim to investigate how sex-determining region Y gene (SRY) in hepatocytes promotes liver fibrosis. ...
Identifying the pivotal role of non-acute decompensation as a precursor to acute decompensation in cirrhosis [0.03%]
识别非急性失代偿在肝硬化中作为急性失代偿前驱的中心作用
Chien-Hao Huang,Ming-Hung Tsai,Chun-Yen Lin
Chien-Hao Huang
Increased Siglec-9/Siglec-9L interactions on NK cells predict poor HCC prognosis and present a targetable checkpoint for immunotherapy [0.03%]
NK细胞上Siglec-9/Siglec-9L相互作用的增加预示着HCC的不良预后,并为免疫治疗提供了可靶向的检查点
Rong Xiao,Ye Tian,Jiwei Zhang et al.
Rong Xiao et al.
Background & aims: Natural killer (NK) cell-based anti-hepatocellular carcinoma (HCC) therapy is an increasingly attractive approach that warrants further study. Siglec-9 interacts with its ligand (Siglec-9L) and restrain...
Changes of hepatic myeloid cells in chronic viral hepatitis and after cure and their clinical significance [0.03%]
慢性病毒性肝炎及其治愈后肝髓系细胞的变化及临床意义
Congyun Liu,Cheng Guo,Kai Liu
Congyun Liu
Endoscopic diagnosis and treatment for portal hypertension: not yet ready for clinical practice! [0.03%]
内镜下诊断和治疗门脉高压:尚未准备好投入临床!
Thomas Reiberger,Jaime Bosch
Thomas Reiberger
Primary hypocholesterolemia is associated with an increased risk of hepatic complications in the general population [0.03%]
原发性低胆固醇血症与普通人群中肝并发症的风险增加有关
Matthieu Wargny,Thomas Goronflot,Antoine Rimbert et al.
Matthieu Wargny et al.
Background & aims: Beyond cardiovascular disease protection, the health consequences of very low concentrations of low-density lipoprotein-cholesterol (LDL-C) remain a matter of debate. In primary hypobetalipoproteinemia ...