Van Gogh-like 2 is essential for the architectural patterning of the mammalian biliary tree [0.03%]
梵高样2对于哺乳动物胆管系统的结构模式至关重要
Michaela Raab,Ersi Christodoulou,Roopesh Krishnankutty et al.
Michaela Raab et al.
Background & aims: In the developing liver, bipotent epithelial progenitor cells undergo lineage segregation to form hepatocytes, which constitute the bulk of the liver parenchyma, and biliary epithelial cells (cholangioc...
Pkd1l1-deficiency drives biliary atresia through ciliary dysfunction in biliary epithelial cells [0.03%]
Pkd1l1缺乏通过胆管上皮细胞纤毛功能障碍驱动胆管闭锁
Yi Zou Lim,Min Zhu,Yunguan Wang et al.
Yi Zou Lim et al.
Background & aims: Syndromic biliary atresia is a cholangiopathy characterized by fibro-obliterative changes in the extrahepatic bile duct (EHBD) and congenital malformations including laterality defects. The etiology rem...
Cutting edges in the HBV genome: How RNA splicing is involved in modulating virus ultrastructure to promote infection [0.03%]
HBV基因组中的剪接边缘：RNA剪接如何参与调节病毒超微结构以促进感染的过程
Stefan Seitz,Ralf Bartenschlager
Stefan Seitz
Endothelial POFUT1 controls injury-induced liver fibrosis by repressing fibrinogen synthesis [0.03%]
内皮细胞POFUT1通过抑制纤维蛋白原的合成控制损伤诱导的肝脏纤维化
Shan He,Yuru Luo,Wangge Ma et al.
Shan He et al.
Background & aims: NOTCH signaling in liver sinusoidal endothelial cells (LSECs) regulates liver fibrosis, a pathological feature of chronic liver diseases. POFUT1 is an essential regulator of NOTCH signaling. Here, we in...
Uric acid in pediatric MASLD definition: Is it time to implement diagnostic criteria? [0.03%]
儿科MASLD定义中的尿酸：是否到了实施诊断标准的时候？
Anna Di Sessa,Stefano Guarino,Giuseppina Rosaria Umano et al.
Anna Di Sessa et al.
Autoimmune hepatitis: Mycophenolate mofetil vs. azathioprine as first-line therapy [0.03%]
自身免疫性肝炎：吗替麦考酚酯与硫唑嘌呤作为一线治疗的对比研究
Cem Şimşek,Staffan Wahlin,Cumali Efe
Cem Şimşek
Comparative Study
Journal of hepatology. 2024 Jul;81(1):e41-e42. DOI:10.1016/j.jhep.2024.02.022 2024
Rare monogenic causes of steatotic liver disease masquerading as MASLD [0.03%]
伪装成代谢相关脂肪性肝病的罕见单基因所致脂肪肝疾病
Martijn C G J Brouwers,David Cassiman
Martijn C G J Brouwers
The synergism of public health policies and social work may reduce mortality from cancer, liver disease and cardiovascular disease [0.03%]
公共卫生政策与社会工作的协同作用可降低癌症、肝病和心血管疾病的死亡率
Shijie Guo,Jingqiang Zeng
Shijie Guo
Syngeneic murine models with distinct immune microenvironments represent subsets of human intrahepatic cholangiocarcinoma [0.03%]
具有不同免疫微环境的同系小鼠模型代表了人类肝内胆管癌的不同亚群
Jennifer L Tomlinson,Binbin Li,Jingchun Yang et al.
Jennifer L Tomlinson et al.
Background & aims: Cholangiocarcinoma (CCA) is a poorly immunogenic malignancy associated with limited survival. Syngeneic immunocompetent mouse models of CCA are an essential tool to elucidate the tumor immune microenvir...
Reply to: "Familial clustering of MASLD: Rethinking strategies for population screening" [0.03%]
《对“MASLD的家庭聚集性：重新思考人群筛查策略”的回应》
Fahim Ebrahimi,Jonas F Ludvigsson
Fahim Ebrahimi