Acute kidney injury in patients with cirrhosis: Acute Disease Quality Initiative (ADQI) and International Club of Ascites (ICA) joint multidisciplinary consensus meeting [0.03%]
肝硬化患者急性肾损伤：急性疾病质量倡议（ADQI）和国际腹水俱乐部（ICA）联合多学科共识会议
Mitra K Nadim,John A Kellum,Lui Forni et al.
Mitra K Nadim et al.
Patients with cirrhosis are prone to developing acute kidney injury (AKI), a complication associated with a markedly increased in-hospital morbidity and mortality, along with a risk of progression to chronic kidney disease. Whereas patients...
Evaluation of a delayed liver transplantation strategy for patients with HCC receiving bridging therapy: the DELTA-HCC study [0.03%]
肝癌患者接受序贯治疗的延迟肝脏移植策略评价：DELTA-HCC研究
Catherine Lamarque,Lauriane Segaux,Philippe Bachellier et al.
Catherine Lamarque et al.
Background & aims: To maximize utility and prevent premature liver transplantation (LT), a delayed LT strategy (DS) was adopted in France in 2015 in patients listed for any single HCC treated with resection or thermal abl...
Post-treatment LSM rather than change during treatment predicts decompensation in patients with cACLD after HCV cure [0.03%]
丙肝治愈后，LSM的基线值及其变化预测cACLD患者失代偿性疾病的价值大于治疗过程中的监测价值
Georg Semmler,Sonia Alonso López,Monica Pons et al.
Georg Semmler et al.
Background & aims: Baveno VII has defined a clinically significant (i.e., prognostically meaningful) decrease in liver stiffness measurement (LSM) in cACLD as a decrease of ≥20% associated with a final LSM
Multicenter Study
Journal of hepatology. 2024 Jul;81(1):76-83. DOI:10.1016/j.jhep.2024.03.015 2024
Transplant benefit-based offering of deceased donor livers in the United Kingdom [0.03%]
基于移植收益的英国肝移植分配制度改革
Elisa Allen,Rhiannon Taylor,Alexander Gimson et al.
Elisa Allen et al.
Background & aims: The National Liver Offering Scheme (NLOS) was introduced in the UK in 2018 to offer livers from deceased donors to patients on the national waiting list based, for most patients, on calculated transplan...
Mycophenolate mofetil in autoimmune hepatitis: Are we ready for primetime? [0.03%]
霉酚酸酯治疗自身免疫性肝炎：我们准备好了吗？
Sagnik Biswas,Shalimar
Sagnik Biswas
Unraveling the liver antiviral immunity in functional cure of chronic hepatitis B using scRNAseq [0.03%]
单细胞转录组揭示功能性治愈慢性乙肝的肝脏抗病毒免疫机制
Pierre Tonnerre,Thomas F Baumert
Pierre Tonnerre
Phenotypes and ontogeny of senescent hepatic stellate cells in metabolic dysfunction-associated steatohepatitis [0.03%]
与代谢紊乱相关性脂肪肝炎背景下肝星状细胞衰老表型及发生发展过程研究
Chittampalli N Yashaswini,Tianyue Qin,Dipankar Bhattacharya et al.
Chittampalli N Yashaswini et al.
Background & aims: Hepatic stellate cells (HSCs) are the key drivers of fibrosis in metabolic dysfunction-associated steatohepatitis (MASH), the fastest growing cause of hepatocellular carcinoma (HCC) worldwide. HSCs are ...
FASN-mediated fatty acid biosynthesis remodels immune environment in Clonorchis sinensis infection-related intrahepatic cholangiocarcinoma [0.03%]
脂肪酸合成酶介导的脂肪酸生物合成重塑肝吸虫感染相关肝内胆管癌免疫微环境
Lixia Xu,Ying Zhang,Zhilong Lin et al.
Lixia Xu et al.
Background & aims: Intrahepatic cholangiocarcinoma (iCCA) is the second most common primary liver cancer and is highly lethal. Clonorchis sinensis (C. sinensis) infection is an important risk factor for iCCA. Here we inve...
Targeting IL-1 in severe alcohol-related hepatitis: How many frogs will we need to kiss to find an effective therapy? [0.03%]
靶向IL-1治疗重症酒精性肝炎：需要接吻多少只青蛙才能找到有效的疗法？
Mark Thursz,Philippe Mathurin
Mark Thursz
Lucile Moga,Valérie Paradis,Onorina Bruno et al.
Lucile Moga et al.