Targeting xanthine oxidoreductase reverses resistance to EGFR tyrosine kinase inhibitors in intrahepatic cholangiocarcinoma [0.03%]
靶向黄嘌呤氧化还原酶可逆转肝内胆管癌表皮生长因子受体酪氨酸激酶抑制剂耐药性
Jianbo He,Minglu Zhang,Yuze Shi et al.
Jianbo He et al.
Background & aims: Despite the overexpression and aberrant activation of epidermal growth factor receptor (EGFR) in intrahepatic cholangiocarcinoma (iCCA), the disease remains refractory to EGFR tyrosine kinase inhibitors...
From Protocol to Precision: The Evolving Diagnosis of Hepatorenal Syndrome [0.03%]
从方案到精准： hepatorenal syndrome 诊断的演变
Mitra K Nadim,John A Kellum,François Durand
Mitra K Nadim
Letter: Calorie Control or Circadian Alignment? A Closer Look at Time-Restricted Eating for MASLD [0.03%]
致编辑关于MASLD的时间限制性饮食：卡路里控制还是昼夜节律同步？更深入的研究
Sofia Tsitsou,Evangelos Cholongitas
Sofia Tsitsou
Nikolaj Torp,Mads Israelsen,Maja Thiele et al.
Nikolaj Torp et al.
Steatotic liver disease (SLD) encompasses metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol-related liver disease (ALD), and their combination (MetALD). Distinguishing these subclasses relies on accurately assessing ...
Ashish Kumar
Ashish Kumar
Male-to-female ratios in the risk of hepatocellular carcinoma: A nationwide study of Danish patients with viral or non-viral cirrhosis [0.03%]
丹麦病毒性和非病毒性肝硬化患者的肝细胞癌男性向女性转化率的全国范围研究
Amalie Borg Bjørn,Morten Daniel Jensen,Adriana Pero et al.
Amalie Borg Bjørn et al.
Patient-derived liver organoids recapitulate liver epithelial heterogeneity and enable precision modeling of alcohol-related liver disease [0.03%]
患者衍生的肝脏类器官再现肝上皮异质性并能精准建模酒精相关性肝病
Silvia Ariño,Raquel Ferrer-Lorente,Guillermo Serrano et al.
Silvia Ariño et al.
Background & aims: Alcohol-associated liver disease (ALD) is a major cause of liver disease worldwide with scarce therapeutic options. Animal models poorly recapitulate advanced ALD precluding the development of new treat...
Reply to: "Challenges in Applying MASLD Risk Algorithms in Pregnancy: A Call for Adaptation and Inclusion" [0.03%]
对“妊娠期应用MASLD风险算法的挑战：适应与包容的呼吁”的答复
Terry Cheuk-Fung Yip,Vincent Wai-Sun Wong
Terry Cheuk-Fung Yip
Stratification, Therapeutic Targeting and Towards Personalised Care in Cirrhosis [0.03%]
肝硬化的分层、治疗靶点及个体化治疗
Nipun Verma,Paolo Angeli,Rajiv Jalan
Nipun Verma