Evaluating Concordance and Clinical Utility of ctDNA Profiling in Advanced Biliary Tract Cancer [0.03%]
评估ctDNA谱分析在晚期胆道癌中的符合率和临床效用
Kui Wang,Yuhua Chen,Yanqing Li
Kui Wang
Avik Majumdar,Manuel Luis Rodríguez-Perálvarez,Emmanuel Tsochatzis
Avik Majumdar
Non-responder on thyroid hormone receptor-β agonist? Bacteroides thetaiotaomicron to the rescue! [0.03%]
甲状腺激素受体-β激动剂无反应？ thetaiotamicron杆菌来帮忙！
Abraham S Meijnikman,Eveline Bruinstroop
Abraham S Meijnikman
PNPLA3(148M) is a gain-of-function mutation that promotes hepatic steatosis by inhibiting ATGL-mediated triglyceride hydrolysis [0.03%]
PNPLA3（148M）通过抑制ATGL介导的甘油三酯水解促进肝脂肪变是一个功能获得性突变
Yang Wang,Sen Hong,Hannah Hudson et al.
Yang Wang et al.
Background & aims: PNPLA3(148M) (patatin-like phospholipase domain-containing protein 3) is the most impactful genetic risk factor for steatotic liver disease (SLD). A key unresolved issue is whether PNPLA3(148M) confers ...
Genetic study of intrahepatic cholestasis of pregnancy in Chinese women unveils East Asian etiology linked to historic HBV epidemic [0.03%]
针对中国孕妇遗传性妊娠期肝内胆汁淤积症的基因研究揭示了与历史性乙肝流行相关的东亚病因学机制
Yanhong Liu,Yuandan Wei,Xiaohang Chen et al.
Yanhong Liu et al.
Background & aims: Intrahepatic cholestasis of pregnancy (ICP) is the most common and high-risk liver disorder during pregnancy, with varying prevalence across populations. Our understanding of the mechanisms underlying I...
Surrender to evidence: the futility of plasma exchange for severe liver disease and liver failure [0.03%]
顺应证据：严重肝病及肝衰竭患者无需血浆置换疗法
Cyriac Abby Philips,Arif Hussain Theruvath,Aryalakshmi Sreemohan et al.
Cyriac Abby Philips et al.
Unlock AI-Safe-C score's potential at all levels: Improve methods and overcome barriers [0.03%]
释放AI-Safe-C评分体系的潜力：改进方法、突破瓶颈
Qin Guo,Hui Li,Chengshan Guo
Qin Guo
Non-invasive algorithms could outperform HVPG in selecting candidates for non-selective beta-blockers in cirrhosis [0.03%]
非侵入性算法或可在选择失代偿期肝硬化患者使用非选择性β阻滞剂方面优于HVPG
Emma Vanderschueren,Wim Laleman
Emma Vanderschueren
Activating hepatobiliary water channels for gallstone prevention in complicated gallstone disease [0.03%]
复杂胆囊结石病的肝胆水通道活化防石研究
Jan G Hengstler,Nachiket Vartak
Jan G Hengstler