Reply to: "The HDL criterion for MetALD can misclassify patients with cirrhosis" [0.03%]
对“MetALD诊断标准会导致肝硬化患者分类错误”的回复
David Marti-Aguado,José Luis Calleja,Ramon Bataller et al.
David Marti-Aguado et al.
Hyodeoxycholic acid ameliorates cholestatic liver fibrosis by facilitating m6A-regulated expression of a novel anti-fibrotic target ETV4 [0.03%]
胆汁郁积性肝纤维化小核糖核酸分子调节机制研究取得进展
Xiaoyong Xue,Runping Liu,Yajie Cai et al.
Xiaoyong Xue et al.
Background & aims: Cholestatic liver fibrosis is a common pathological feature of various biliary tract diseases. the underlying pathological mechanisms are not fully elucidated, posing significant obstacles to the discov...
Response to: Unlock AI-Safe-C score's potential at all levels: Improve methods and overcome barriers [0.03%]
回应：解锁AI-Safe-C评分在各层面的潜力：改进方法和克服障碍
Huapeng Lin,Terry Cheuk-Fung Yip,Vincent Wai-Sun Wong et al.
Huapeng Lin et al.
Association of Metabolic Signatures of Air Pollution with MASLD: A Note on Data Consistency [0.03%]
空气污染代谢标志物与MASLD相关性的数据一致性的说明注释
Jianmin Zhao,Jianjun Zhao
Jianmin Zhao
Multiomic analysis uncovers a continuous spectrum of differentiation and Wnt-MDK-driven immune evasion in hepatoblastoma [0.03%]
多组学分析揭示了肝母细胞瘤中连续的分化谱系和Wnt-MDK驱动的免疫逃逸现象
Daniel Münter,Flavia W de Faria,Mathis Richter et al.
Daniel Münter et al.
Background & aims: Hepatoblastoma is the most common pediatric cancer of the liver and the majority of cases display activating mutations in the Wnt/β-catenin pathway. Understanding the complex milieu of the tumor microe...
Metabolic dysfunction-associated steatotic liver disease may increase intrahepatic interferon gene signatures in patients with chronic hepatitis B [0.03%]
代谢功能异常的肝脂肪变性疾病可能增加慢性乙型肝炎患者肝脏内干扰素基因信号
Yan Han,Jing Tang,Peng Hu et al.
Yan Han et al.
Elisa Pose,Salvatore Piano,Maja Thiele et al.
Elisa Pose et al.
Chronic liver diseases (CLD) are a leading cause of death worldwide, with alcohol consumption and metabolic risk factors as the two reasons accounting for the majority of cases of CLD in many developed countries. Currently there is a lack o...
Loss or gain of function: The functional complexity of the PNPLA3 I148M Variant [0.03%]
功能获得或丧失：PNPLA3 I148M变异的功能复杂性
Sepideh Mikaeeli,David E Cohen
Sepideh Mikaeeli
Beyond Portal Hypertension: Characterizing Porto-Sinusoidal Vascular Disorder in Patients without signs of PH [0.03%]
超越门脉高血压：在没有PH迹象的患者中表征门-窦血管病变
Nicola Pugliese,Stella De Nicola,Luca di Tommaso et al.
Nicola Pugliese et al.
Loss of SGK1 supports metastatic colonization in hepatocellular carcinoma by promoting resistance to T cell-mediated immunity [0.03%]
SGK1丢失通过促进对T细胞介导的免疫抵抗支持肝癌转移殖民化
Zefan Zhang,Chenlu Geng,Minfang Song et al.
Zefan Zhang et al.
Background & aims: Immune evasion by tumor cells is a principal obstacle to effectively targeting metastasis in hepatocellular carcinoma (HCC). However, the specific molecular mechanisms facilitating immune escape during ...