Carvedilol is superior to propranolol in preventing first and further decompensation, and mortality in patients with cirrhosis [0.03%]
对于肝硬化患者，卡维地洛优于普萘洛尔，可预防首次和再次失代偿及降低死亡风险
Maria Christaki,Dimitrios Biros,Ilias Tsiakas et al.
Maria Christaki et al.
New platinum derivatives selectively cause double-strand DNA breaks and death in naïve and cisplatin-resistant cholangiocarcinomas [0.03%]
新型铂类化合物能选择性诱导胆管癌细胞双链DNA断裂并杀伤顺铂敏感及耐药的胆管癌细胞系
Irene Olaizola,Mikel Odriozola-Gimeno,Paula Olaizola et al.
Irene Olaizola et al.
Background & aims: Patients with cholangiocarcinoma (CCA) have poor prognosis. Current cisplatin-based first-line chemotherapy offers limited survival benefits. Cisplatin induces single-strand DNA breaks, activating DNA r...
The Emerging Role of Second Harmonic Generation/Two Photon Excitation for Precision Digital Analysis of Liver Fibrosis in MASH Clinical Trials [0.03%]
调制亚micron空间谐振临床试验中肝纤维化精准数字分析中二次谐波生成/两光子激发的新兴作用
Brent A Neuschwander-Tetri,Kutbuddin Akbary,Danielle H Carpenter et al.
Brent A Neuschwander-Tetri et al.
Conventional histopathological evaluation of liver biopsy slides has been invaluable in assessing the causes of liver injury, the severity of the underlying disease processes, and the degree of resulting fibrosis. However, the use of conven...
Combined Liver with Other Solid Organ Transplants: Promises, Pitfalls and ethical dilemmas, An Expert Opinion [0.03%]
联合肝移植与其它实体器官移植的承诺、困境及伦理难题——专家意见
Francesco Paolo Russo,Sarwa Darwish Murad,Anjana A Pillai et al.
Francesco Paolo Russo et al.
This expert opinion explores the growing practice of multi-organ transplantation (MOT) in which liver transplantation is combined with another solid organ transplantation, such as heart, lung or kidney transplantation. There is an increasin...
Camila A Picchio,Aina Nicolàs,Jeffrey V Lazarus
Camila A Picchio
Alastair M Kilpatrick,Victoria L Gadd,Stuart J Forbes
Alastair M Kilpatrick
Claudia Am Fulgenzi,Alessia Dalla Pria,Alberto Giovanni Leone et al.
Claudia Am Fulgenzi et al.
People living with HIV (PLWH) carry a higher risk of developing chronic liver disease and hepatocellular carcinoma (HCC). This relates to shared transmission pathways of HIV and viral hepatitis and a plethora of direct and indirect effects ...
Corrigendum to "Association of metabolic signatures of air pollution with MASLD: Observational and Mendelian randomization study" [J Hepatol (2025) 10.1016/j.jhep.2024.09.033] [0.03%]
关于“空气污染的代谢标志物与MASLD相关性：观察性和孟德尔随机化研究”的勘误[J Hepatol (2025) 10.1016/j.jhep.2024.09.033]
Shanshan Ran,Jingyi Zhang,Fei Tian et al.
Shanshan Ran et al.
Published Erratum
Journal of hepatology. 2025 Apr 28:S0168-8278(25)00225-9. DOI:10.1016/j.jhep.2025.04.001 2025
David J Pinato
David J Pinato