Cristina Has,Meropi Karakioulaki
Cristina Has
Dystrophic epidermolysis bullosa (DEB) is a rare, debilitating genodermatosis caused by loss-of-function variants in COL7A1, resulting in type VII collagen (C7) deficiency and defective anchoring fibrils, which are essential for dermal-epid...
Low-Risk Basal Cell Carcinoma: Surgery First, but Not Surgery Only-Toward Protocolised Active Surveillance [0.03%]
低风险基底细胞癌:首先进行手术,但并非唯有手术之途——迈向规范性积极监测
Vincenzo De Giorgi,Gabriella Perillo,Giovanni Cecchi et al.
Vincenzo De Giorgi et al.
Repetin Regulates Epidermal Barrier Homeostasis and Is Associated With Inflammatory Skin Diseases [0.03%]
Repetin调节表皮屏障稳态并与炎症性皮肤病相关
Megumi Mizawa,Teruhiko Makino,Keita Takemoto et al.
Megumi Mizawa et al.
Repetin (RPTN) is a member of the fusion S100 protein family encoded within the epidermal differentiation complex. Although genetic studies have revealed that RPTN is a susceptibility gene for atopic dermatitis (AD), its biological function...
LC-OCT for Cutaneous Lupus Erythematosus: Characterization Across Disease Subtypes and Differentiation From Rosacea [0.03%]
用于盘状红斑狼疮和慢性限局性红斑狼疮的线性偏振光学相干断层扫描:不同亚型的特征及与酒渣鼻的区别
Daniele Omar Traini,Gerardo Palmisano,Rebecca Ventura et al.
Daniele Omar Traini et al.
Cutaneous lupus erythematosus (CLE) encompasses a heterogeneous group of autoimmune skin manifestations that often overlap clinically with other inflammatory dermatoses, particularly rosacea. While histopathology remains the gold standard, ...
Observational Study
Experimental dermatology. 2026 Aug;35(8):e70337. DOI:10.1111/exd.70337 2026
Dermoscopic-Pathologic Correlates of Invasiveness and Nevus Visibility in Nevus-Associated Melanoma [0.03%]
与黑色素瘤痣相关的侵袭性和痣可见性的皮肤镜病理相关性
Marco Spadafora,Erica Baschieri,Simonetta Piana et al.
Marco Spadafora et al.
Nevus-associated melanoma (NAM) is histologically defined by coexisting nevus and melanoma components, yet the nevus component is frequently not visible on dermoscopy. We performed a retrospective, single-centre observational study includin...
Observational Study
Experimental dermatology. 2026 Aug;35(8):e70333. DOI:10.1111/exd.70333 2026
Minoxidil Sulfate Regulates JAK/STAT Signalling and Mitochondrial Function in Alopecia Areata [0.03%]
硫酸ミノキシジルが円形脱毛症におけるJAK/STAT信号伝達とミトコンドリア機能を制御することを特定する
Jung-Min Shin,Bogyeong Go,Kyung Eun Jung et al.
Jung-Min Shin et al.
Alopecia areata (AA) is an autoimmune hair disorder characterized by interferon-gamma (IFN-γ)-driven inflammation and collapse of hair follicle immune privilege. Although Janus kinase (JAK) inhibitors are effective, incomplete or delayed r...
Integrated Proteogenomics and Single-Cell Transcriptomics Prioritize Putative Protective Plasma Proteins for Hidradenitis Suppurativa [0.03%]
整合蛋白组学和单细胞转录组学优先考虑对汗腺炎具有潜在保护作用的血浆蛋白质
Yuzhe Cheng,Jingyi Ma,Jun Niu
Yuzhe Cheng
Translating hidradenitis suppurativa (HS) genetic susceptibility into actionable targets remains challenging, as most genome-wide association study loci lie in non-coding regions and tissue-level transcriptomics cannot easily distinguish ca...
Clinical Significance of Malassezia-Specific IgE in Assessing the Severity of Head and Neck Involvement in Korean Atopic Dermatitis Patients [0.03%]
马尔尼菲青霉特异性IgE在评估韩国特应性皮炎患者头颈部受累严重程度中的临床意义
Han-Na Kim,Jaewon Choi,Anna Kim et al.
Han-Na Kim et al.
Head and neck dermatitis (HND) is a distinct clinical phenotype of atopic dermatitis (AD). While Malassezia sensitisation and elevated Malassezia-specific IgE antibody (MSIA) levels have been documented in HND patients, the relationship bet...
Observational Study
Experimental dermatology. 2026 Jul;35(7):e70334. DOI:10.1111/exd.70334 2026
Prevotella copri Exacerbates Psoriasis Through Keratinocyte-Neutrophil Crosstalk via NF-κB Activation [0.03%]
黏附性不动杆菌通过NF-κB激活促进角质形成细胞-中性粒细胞相互作用从而加重银屑病
Meijunzi Luo,Jie Gao,Yujin Zhang et al.
Meijunzi Luo et al.
Psoriasis is a chronic inflammatory skin disorder driven by systemic immune dysregulation and recent studies have implicated the gut-skin axis in its pathogenesis. However, the specific role of individual gut microbes remains poorly underst...
Treatment With Ashwagandha-Derived Exosome-Like Nanovesicles Up-Regulates VEGF-A Production and Promotes Human Hair Growth Ex Vivo [0.03%]
阿育吠陀草药仙露明提取的外泌体样纳米囊泡通过上调血管内皮生长因子A促进头发生长作用研究
Alizée Le Riche,Janina Nienhaus,Marta Silva E Sousa et al.
Alizée Le Riche et al.
Human-derived exosomes show promise for hair loss treatment but may pose safety concerns, including inflammatory responses and pathogen transmission. Here, we investigated whether plant-derived exosomes, whose isolation can be standardized,...