Anne E Holland,Jerry A Krishnan,Yves Lacasse et al.
Anne E Holland et al.
Home oxygen therapy is a well-accepted treatment for advanced respiratory disease; however, there are substantial evidence gaps and implementation challenges. The patient experience varies widely; oxygen therapy devices are often poorly mat...
Murine models of pulmonary fibrosis: mechanisms, limitations and translational insights [0.03%]
肺纤维化的鼠类模型:机制、局限性和转化视角
Karen F Lou,McKenzie M Fulcer,Mary J Lotesto et al.
Karen F Lou et al.
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible interstitial lung disease characterised by excessive collagen deposition, aberrant tissue remodelling, and impaired gas exchange, ultimately leading to respiratory ...
Weight loss for obstructive sleep apnoea: first-line therapy should not mean single-line therapy [0.03%]
肥胖症患者阻塞性睡眠呼吸暂停的减肥治疗:一线治疗不应是唯一治疗
ZhiKang Yin,Liang Wei
ZhiKang Yin
Weight loss should be foundational in obstructive sleep apnoea care, but not a standalone substitute for event-controlling therapies. Treatment sequencing should reflect hypoxic burden, symptoms, risk, access and patient preference. https:/...
Giovanni Franco,Umberto Zanini,Giulia Peri et al.
Giovanni Franco et al.
Interstitial lung diseases (ILDs) comprise a heterogeneous group of lung disorders marked by progressive fibrosis and increased vulnerability to respiratory infections, which can trigger sudden outbreaks and worsen outcomes. Vaccination is ...
Ageing-associated regenerative failure in the lung: stem cell senescence and transitional cell persistence in idiopathic pulmonary fibrosis [0.03%]
Masahiro Yoshida,Jun Araya
Masahiro Yoshida
Alveolar regeneration failure due to alveolar stem cell senescence is a defining feature of idiopathic pulmonary fibrosis (IPF), yet the epithelial mechanisms underlying this dysfunction remain incompletely understood. Recent single-cell an...
Normal limits for the right ventricle-pulmonary circulation exercise echocardiography: a meta-analysis [0.03%]
正常右心室-肺循环运动负荷超声心动图指标的meta分析
Francesco Ferrara,Valentina Capone,Monica Franzese et al.
Francesco Ferrara et al.
Normal limits for exercise Doppler echocardiography (ex-TTE) measurements of the right ventricle (RV), pulmonary artery (PA) and left atrial (LA) unit remain inadequately defined. This meta-analysis aims to establish normal limits for measu...
Patient-reported outcome measures applied in chronic diseases relevant to asthma remission: a scoping review [0.03%]
应用于与哮喘缓解相关的慢性疾病的患者报告结果测量:系统评价
Allison Michaud,John Politis,Lachlan Faktor et al.
Allison Michaud et al.
Background: Asthma remission is a meaningful treatment goal that requires patient and healthcare provider agreement. However, there is currently no validated way to incorporate patient perspectives of remission in this pr...
How experimental models have unlocked hidden mechanisms of hypersensitivity pneumonitis [0.03%]
实验模型如何揭示过敏性肺炎的隐秘机制
Sandra Cabrera,Annie Pardo,Moisés Selman
Sandra Cabrera
Hypersensitivity pneumonitis (HP) is a complex immune-mediated interstitial lung disease triggered by repeated or persistent inhalation of a variety of inhaled antigens in genetically predisposed individuals. The disease encompasses a wide ...
Paediatric obstructive sleep apnoea and early cardiovascular risk phenotypes: an evidence review [0.03%]
儿童阻塞性睡眠呼吸暂停与早期心血管风险表型:证据回顾
Ping Wei,Hua Yang,Yi Yang et al.
Ping Wei et al.
Adult obstructive sleep apnoea (OSA) is an established cardiovascular risk factor, but paediatric OSA has been framed mainly around neurocognition and growth. We reviewed PubMed, Ovid-Embase and Web of Science (2000-2026), prioritising elig...