Comparative response to pharmacological management of asthma in overweight/obese children versus their counterparts: a systematic review and call for data [0.03%]
肥胖和非肥胖儿童对哮喘药物治疗反应的差异：系统评价及数据分析呼吁
Jose A Castro-Rodriguez,Samantha H Averill,M Isabel Castro-Guevara et al.
Jose A Castro-Rodriguez et al.
Background: Obese children with asthma experience higher morbidity than their counterparts; whether different treatments should be considered remains to be clarified. ...
Jessica Tolentino,Madison Coward-Smith,Brian G G Oliver et al.
Jessica Tolentino et al.
Respiratory infections during critical periods of lung development can shape immune responses and cause lasting alterations in pulmonary structure and function. Lung development begins in utero, with airway branching, alveolarisation and ep...
Selective phosphodiesterase 4B inhibition in fibrotic lung disease: a scoping review of vascular-immune mechanisms and extrapulmonary implications [0.03%]
选择性磷酸二酯酶4B抑制在肺纤维化疾病中的作用：血管-免疫机制和肺外影响的综述性研究
Fabio Perrotta,Domenica Francesca Mariniello,Raffaella Pagliaro et al.
Fabio Perrotta et al.
Background: Preferential phosphodiesterase 4B (PDE4B) inhibition with nerandomilast has demonstrated attenuation of forced vital capacity decline in idiopathic pulmonary fibrosis and progressive pulmonary fibrosis. Becaus...
Beyond nocturnal hypercapnia: positioning obstructive sleep apnoea within a sleep-circadian-hypothalamic network [0.03%]
超越夜间高碳酸血症：在睡眠-昼夜节律-下丘脑网络中定位阻塞性睡眠呼吸暂停
Yu-Hsiang Lin,Kuo-Jen Lin,Jau-Yuan Chen
Yu-Hsiang Lin
Nocturnal hypercapnia in OSA/OHS is one signal within a broader sleep–circadian–hypothalamic network linking respiration with endocrine, autonomic and mitochondrial dysregulation, warranting integrated phenotyping beyond carbon dioxide. h...
Change in pulmonary artery pressure upon acute exposure to high altitude: a systematic review and meta-analysis [0.03%]
高原急性暴露肺动脉压变化的系统综述和 meta 分析
Eva Cafuta Wagner,Julian Müller,Michael Furian et al.
Eva Cafuta Wagner et al.
Background/research question: We investigated the increase in pulmonary artery pressure (PAP) with altitude gain in healthy low-altitude residents travelling to high altitude, analysing reported measures including systoli...
The triple-hit hypothesis: exploring pulmonary e-cigarette, PM2.5 and viral polyexposure [0.03%]
三重打击假说——探讨肺部电子烟、PM2.5和病毒的复合暴露
Hilma Clemén,Sangeetha Ramu,Lena Uller
Hilma Clemén
Exposure to e-cigarette aerosols, particulate matter with aerodynamic diameter ≤2.5 µm (PM2.5) and respiratory viruses rarely occurs in isolation, but rather in complex polyexposure contexts during daily life. On a cellular and molecular ...
COPD maintenance trials use heterogeneous outcomes and measurement instruments: a systematic literature review [0.03%]
慢阻肺维持期研究使用异质性的疗效指标和评估工具：系统综述研究
Vi Truong,Sulaiman Bin Safar,Sachin Ananth et al.
Vi Truong et al.
Background: Randomised controlled trials (RCTs) of COPD management assess heterogeneous outcomes with diverse instruments and often omit those important to patients and healthcare professionals, limiting interpretability ...
Fibrotic chronic eosinophilic pneumonia: from inflammation to fibrosis and therapeutic implications [0.03%]
从炎症到纤维化：慢性嗜酸性粒细胞肺炎的发病机制及治疗意义
Daniele Previtero,Gioele Castelli,Ylenia Padrin et al.
Daniele Previtero et al.
Chronic eosinophilic pneumonia is a rare inflammatory lung disease that typically responds to systemic glucocorticoids but is frequently complicated by relapses and treatment-related toxicity. In recent years, monoclonal antibodies targetin...
Genetic susceptibility to respiratory health effects from outdoor air pollution: a structured narrative review [0.03%]
户外空气污染的遗传易感性：呼吸健康影响的结构叙述性审查
Yidan Meng,Ji Soo Lim,Christine Chen et al.
Yidan Meng et al.
Outdoor air pollution exposure is a well-established driver of respiratory disease, while growing evidence highlights an important role for genetic susceptibility. Building on this expanding body of work, our review synthesises findings acr...
Prediction of PD-L1 expression in nonsmall cell lung cancer using artificial intelligence models based on radiomics: a systematic review and meta-analysis [0.03%]
基于影像组学的人工智能模型预测非小细胞肺癌程序性死亡配体1表达的系统评价和meta分析
Peng Zhang,Biao Zhang,Nian Liu et al.
Peng Zhang et al.
Background: Since 1992, the incidence of lung cancer has shown an overall downward trend, with survival rates significantly improving in recent years due to the application of immune checkpoint inhibitors (ICIs). Assessin...