Upadacitinib and vedolizumab combination therapy for the management of refractory ulcerative colitis and Crohn's disease [0.03%]
乌帕替尼联合 Vedolizumab 治疗难治性溃疡性结肠炎和克罗恩病的疗效
Robert Gilmore,Amrutha Murali,Amirah Etchegaray et al.
Robert Gilmore et al.
Background/aims: Inflammatory bowel disease (IBD) is characterised by chronic inflammation of the gastrointestinal tract, and encompasses both ulcerative colitis (UC) and Crohn's disease (CD). Refractory disease is common...
Clinical spectrum of acute severe ulcerative colitis in the biologic era: a prospective cohort study from India [0.03%]
生物制剂时代急性重症溃疡性结肠炎的临床谱系：一项印度前瞻性队列研究
Arshdeep Singh,Mayur Luthra,Arshia Bhardwaj et al.
Arshdeep Singh et al.
Background/aims: Acute severe ulcerative colitis (ASUC) is a time-critical situation requiring urgent intervention. Limited data exist on the evolving clinical spectrum of ASUC in the era of advanced therapies. ...
The duration of prior anti-tumor necrosis factor agents is associated with the effectiveness of vedolizumab in patients with ulcerative colitis: a real-world multicenter retrospective study [0.03%]
溃疡性结肠炎患者先前使用抗肿瘤坏死因子药物的时长与维多珠单抗疗效的相关性：一项真实世界多中心回顾性研究
Taku Kobayashi,Tadakazu Hisamatsu,Satoshi Motoya et al.
Taku Kobayashi et al.
Background/aims: Previous literature suggests that the response of patients with ulcerative colitis to vedolizumab may be affected by previous biologic therapy exposure. This real-world study evaluated vedolizumab treatme...
Decoding genetic divergence: TPMT and NUDT15 polymorphisms in north India mirror Caucasian ancestry [0.03%]
解码遗传差异：北印度人群中的TPMT和NUDT15多态性反映高加索人祖先的影响
Arshdeep Singh,Renu Moti Pandita,Manjeet Kumar Goyal et al.
Arshdeep Singh et al.
Lifestyle restrictions are associated with impaired quality of life but not reduction in relapse in ulcerative colitis [0.03%]
生活方式限制与溃疡性结肠炎患者的生活质量下降有关，但与其病情缓解无关
Hajime Yamazaki,Masakazu Nagahori,Tadakazu Hisamatsu et al.
Hajime Yamazaki et al.
Background/aims: Patients with ulcerative colitis (UC) in remission commonly restrict thir lifestyle to prevent relapse; however, the effectiveness and impact on quality of life (QOL) is unclear. This study investigated w...
Response: Comments on "Adequacy of sigmoidoscopy as compared to colonoscopy for assessment of disease activity in patients of ulcerative colitis: a prospective study" [0.03%]
关于“评估溃疡性结肠炎患者疾病活动度时内镜检查充分性的前瞻性研究”的评论
Sameet Tariq Patel,Sanjay Chandnani,Pravin M Rathi
Sameet Tariq Patel
Does statin have a chemopreventive effect in patients with ulcerative colitis? [0.03%]
溃疡性结肠炎患者的他汀类药物化学预防作用探讨
Yoon Suk Jung
Yoon Suk Jung
Anti-integrin αvβ6 autoantibody in patients with ulcerative colitis after proctocolectomy: a cross-sectional study in Japan [0.03%]
日本溃疡性结肠炎患者的回肠肛门 pouch术后的抗αvβ6整合素自身抗体：横断面研究
Tsuyoshi Yanagida,Yu Nishida,Yumie Kobayashi et al.
Tsuyoshi Yanagida et al.
Background/aims: Pouchitis is a common complication in patients with ulcerative colitis (UC) following colectomy with ileal pouch-anal anastomosis (IPAA). Recent studies have identified a novel autoantibody against integr...
Gut, bone, and muscle: the triad of osteosarcopenia in inflammatory bowel disease [0.03%]
胃肠、骨骼和肌肉：炎症性肠病的骨肌减少症三联征
Shilpa Sharma
Shilpa Sharma
Inflammatory bowel disease (IBD) is a group of chronic inflammatory conditions affecting the gastrointestinal tract that can lead to multiple systemic complications. Among these, osteosarcopenia has emerged as a significant concern, charact...