Prospective evaluation of artificial intelligence-assisted monitoring of the effective withdrawal time on adenoma detection [0.03%]
Thomas Ka Luen Lui,Carla Pui-Mei Lam,Vivien Wai-Man Tsui et al.
Thomas Ka Luen Lui et al.
Background/aims: Standard withdrawal time (SWT) is a recognized colonoscopy quality metric but may not capture mucosal examination quality. We developed an artificial intelligence (AI)-derived metric, effective withdrawal...
Impact of filgotinib on health-related quality of life over 3 years in Japanese patients with ulcerative colitis: a post hoc analysis of the SELECTION and SELECTION long-term extension trials [0.03%]
.filgotinib对日本溃疡性结肠炎患者3年健康相关生活质量的影响：SELECTION和SELECTION长期扩展试验的事后分析
Katsuyoshi Matsuoka,Stefan Schreiber,Erina Hata et al.
Katsuyoshi Matsuoka et al.
Background/aims: This post hoc analysis of the phase 2b/3 SELECTION (NCT02914522) study and its long-term extension (SELECTIONLTE; NCT02914535) evaluated the impact of filgotinib 200 mg (FIL200) on health-related quality ...
Deciphering the diet-inflammatory bowel disease relationship: knowledge gaps and future perspectives [0.03%]
解读饮食与炎症性肠病关系：知识空白及未来展望
Arshdeep Singh,Arshia Bhardwaj,Vandana Midha et al.
Arshdeep Singh et al.
Diet is increasingly recognized not as a passive exposure but as a dynamic determinant of inflammatory bowel disease (IBD) pathogenesis, progression, and treatment response. This review article redefines diet as a multidimensional modifier ...
Temporal hospitalization trends for inflammatory bowel disease in Taiwan [0.03%]
台湾地区炎症性肠病住院趋势的时空变化规律探究
Hao-Yu Wu,Meng-Tzu Weng,Chien-Chih Tung et al.
Hao-Yu Wu et al.
Background/aims: Scant population-based data are available for inflammatory bowel disease (IBD)-related hospitalization rates in Asian countries. We investigated the epidemiological trends of hospitalization rate and leng...
Characteristics of monogenic inflammatory bowel disease in very early-onset cases: a Japanese multicenter registry study [0.03%]
日本多中心注册研究中的单基因炎症性肠病极早期发病患者的特征分析
Natsuki Ito,Takahiro Kudo,Keisuke Jimbo et al.
Natsuki Ito et al.
Background/aims: Very early-onset inflammatory bowel disease (VEO-IBD), defined as IBD diagnosed before 6 years of age, is highly influenced by genetic factors. Monogenic IBD is a type of enterocolitis caused by a single ...
Colitis-associated colorectal neoplasia in ulcerative colitis with primary sclerosing cholangitis: a nationwide study [0.03%]
溃疡性结肠炎伴原发性硬化性胆管炎的结直肠癌前病变全国流行病学研究报告
Koichi Komatsu,Takahide Shinagawa,Motoi Uchino et al.
Koichi Komatsu et al.
Background/aims: Ulcerative colitis (UC)-associated colorectal neoplasia (UCAN) in patients with UC and primary sclerosing cholangitis (PSC) has not been studied well in Japan. This retrospective study examined the clinic...
Evaluation of the Mayo endoscopic score in ulcerative colitis using a multimodal large language model: a human-blinded accuracy study [0.03%]
利用多模态大型语言模型评估Mayo内镜评分在溃疡性结肠炎中的准确性：一项盲法人类研究
Antonietta Gerarda Gravina,Raffaele Pellegrino,Giuseppe Imperio et al.
Antonietta Gerarda Gravina et al.
Background/aims: To date, some large language models (LLMs), such as Chat Generative Pre-trained Transformer 4-omni (ChatGPT-4o), can process images through visual transformer patching. An LLM analysis was conducted to as...
Efficacy and safety of subcutaneous guselkumab in East Asian participants with moderately to severely active Crohn's disease: subgroup analysis of the Phase 3 GRAVITI study [0.03%]
针对中度至重度活动性克罗恩病的东亚患者的皮下注射古塞库单抗疗效和安全性：III期GRAVITI研究的事后亚组分析
Wenjia Liu,Hong Guo,Tae Oh Kim et al.
Wenjia Liu et al.
Background/aims: The GRAVITI (NCT05197049) study demonstrated efficacy and safety of guselkumab, a dual-acting interleukin- 23p19 subunit inhibitor, as subcutaneous (SC) induction and maintenance therapy in participants w...
Safety and effectiveness of budesonide rectal foam for ulcerative colitis in a large-scale, multicenter, prospective observational study: final report of post-marketing surveillance in Japan [0.03%]
布地奈德 Rectal 泡沫剂治疗溃疡性结肠炎的上市后大规模多中心前瞻性观察研究：最终报告
Masayuki Saruta,Teppei Omori,Akira Nagaki et al.
Masayuki Saruta et al.
Background/aims: Budesonide rectal foam was approved in Japan in 2017 for mild to moderate active ulcerative colitis (UC). This is the final report of post-marketing surveillance to evaluate real-world safety and effectiv...
Efficacy and safety of mirikizumab in maintenance therapy for ulcerative colitis in difficult-to-treat inflammatory bowel disease: a single-center retrospective study in Japan [0.03%]
难治性溃疡性结肠炎患者中米奎利珠维持治疗的疗效和安全性：日本单中心回顾性研究
Ichiro Mizushima,Yusuke Yoshimatsu,Hiroki Kiyohara et al.
Ichiro Mizushima et al.
Background/aims: Randomized controlled trials have confirmed the efficacy and safety of mirikizumab, an anti-interleukin-23p19 monoclonal antibody, for moderate-to-severe active ulcerative colitis (UC). However, there are...