Transabdominal ultrasonography for small-bowel lesions in Crohn's disease: a prospective comparison with balloon-assisted enteroscopy [0.03%]
克罗恩病小肠病变的经腹超声内镜检查与气囊辅助内镜检查的对比研究
Masahiro Takahara,Sakiko Hiraoka,Keiko Takeuchi et al.
Masahiro Takahara et al.
Background/aims: Transabdominal ultrasonography (TUS) is increasingly used to assess small-bowel lesions in Crohn's disease (CD); however, the diagnostic performance of prospective segment-specific data relative to balloo...
Long-term efficacy and safety of vedolizumab compared with infliximab in biologic-naive ulcerative colitis: a systematic review and meta-analysis [0.03%]
与英夫利昔单抗相比， vedolizumab治疗初治溃疡性结肠炎远期疗效和安全性的系统评价和meta分析
Akhil Deepak Vatvani,Timotius Ivan Hariyanto,Daniel Gonzalez Mosquera et al.
Akhil Deepak Vatvani et al.
Background/aims: Vedolizumab and infliximab are widely used biologic agents for ulcerative colitis (UC), yet their comparative long-term effectiveness and safety in biologic-naive patients remain uncertain. This meta-anal...
Environmental pollutants and the rising burden of inflammatory bowel disease in East Asia: a narrative review [0.03%]
环境污染物与东亚地区炎症性肠病负担加重：一篇述评式综述
Shabari Shenoy,Mansi Chaubey,Eun Soo Kim et al.
Shabari Shenoy et al.
Inflammatory bowel disease (IBD) is rising at an alarming rate in parallel with rapid urbanization in newly industrialized parts of the world, including East Asia. Simultaneously, environmental pollutants are also an escalating problem in t...
Efficacy and safety of ustekinumab in Asian patients with moderately to severely active Crohn's disease: a small subpopulation analysis of UNITI/IM-UNITI long-term extension through 5 years [0.03%]
乌司奴单抗治疗中重度活动性克罗恩病亚洲患者的有效性和安全性：UNITI/IM-UNITI长期扩展研究（长达五年）的亚组分析
Byong Duk Ye,Ken Sugimoto,Jae Hee Cheon et al.
Byong Duk Ye et al.
Background/aims: This final long-term extension (LTE) analysis assessed the long-term efficacy and safety of ustekinumab (UST) in the Asian patient subpopulation of the UNITI/IM-UNITI study. ...
Efficacy and safety of ozanimod in Japanese patients with moderately to severely active ulcerative colitis naive to immunomodulators or advanced therapies: post hoc analysis of the phase 2/3 J-True North study [0.03%]
奥扎莫德对日本中至重度活动性溃疡性结肠炎患者（未接受过免疫调节剂或生物制剂治疗）疗效和安全性的探索：J-True North 研究的事后分析
Tadakazu Hisamatsu,Toshimitsu Fujii,Hiroshi Nakase et al.
Tadakazu Hisamatsu et al.
Background/aims: There is limited evidence for ozanimod, an oral sphingosine 1-phosphate receptor modulator, in patients with ulcerative colitis (UC) before treatment is escalated to an immunomodulator (IM) or advanced th...
Guselkumab efficacy and safety in East Asian participants with moderately to severely active Crohn's disease: subgroup analysis of the phase 3 GALAXI 2 and GALAXI 3 trials [0.03%]
Guselkumab在东亚中至重度活动性克罗恩病患者中的疗效和安全性：GALAXI 2和GALAXI 3三期试验的事后亚组分析
Hiroshi Nakase,Baili Chen,Qian Cao et al.
Hiroshi Nakase et al.
Background/aims: Guselkumab, a dual-acting interleukin-23p19 subunit inhibitor, demonstrated efficacy and safety in participants with moderately to severely active Crohn's disease in the global phase 3 GALAXI 2 and 3 tria...
Long-term clinical and endoscopic efficacy of vedolizumab and therapeutic persistence in patients with ulcerative colitis in China: a multicenter observational study [0.03%]
维多珠单抗治疗中国溃疡性结肠炎患者的长期临床和内镜疗效以及药物维持：一项多中心观察性研究
Zhaopeng Huang,Lingya Yao,Yun Qiu et al.
Zhaopeng Huang et al.
Background/aims: Limited data are available on the long-term efficacy of vedolizumab (VDZ) in Asian patients with ulcerative colitis (UC), particularly regarding endoscopic outcomes. ...
Post-treatment simplified MaRIA score predicts clinical outcome in Crohn's disease patients [0.03%]
改良MaRIA评分可预测克罗恩病临床预后
Ami Kawamoto,Kento Takenaka,Junichi Tsuchiya et al.
Ami Kawamoto et al.
Hyoung Il Choi,Jae Myung Cha
Hyoung Il Choi
Liquid biopsy refers to the analysis of tumor-derived components in blood to enable minimally invasive cancer detection and characterization. Circulating tumor cells, circulating tumor DNA, and tumor-derived extracellular vesicles have demo...
Effectiveness of adjunctive use of antibiotics in acute severe ulcerative colitis: a propensity score matching analysis [0.03%]
抗菌药物辅助治疗重度急性溃疡性结肠炎的疗效分析：倾向分值匹配研究
Hye Kyung Hyun,Jihye Park,Soo Jung Park et al.
Hye Kyung Hyun et al.
Background/aims: The exact cause of ulcerative colitis (UC) remains unclear but likely involves an immune response to an unidentified component of gut microbiota. The use of antibiotics in treating acute severe UC (ASUC) ...