Extranodal involvement defines distinct immune-molecular phenotypes and clinical outcomes in diffuse large b-cell lymphoma [0.03%]
结外受累定义了弥漫性大B细胞淋巴瘤中不同的免疫分子表型和临床结局
Yiliya Ahongjiang,Lihua Qiu,Min Li et al.
Yiliya Ahongjiang et al.
Extranodal involvement (ENI) is incorporated into routine risk assessment for diffuse large B-cell lymphoma (DLBCL), but treating ENI as a single binary adverse feature may conceal clinically relevant heterogeneity in extranodal burden, ana...
Fatty acids metabolic reprogramming and tumor microenvironment in pancreatic cancer: targeting pathways [0.03%]
脂肪酸代谢重构与胰腺癌肿瘤微环境：靶向作用途径
Bassant Ehab,Ekram Saleh
Bassant Ehab
Pancreatic ductal adenocarcinoma (PDAC) represents a highly aggressive form of pancreatic cancer. It is distinguished by a profound metabolic plasticity that supports its survival in a hypoxic and nutrient deprived microenvironment. Among t...
Correction: Clonal Metamorphosis: Deconstructing MPN Evolution with Single-Cell and Spatial Multi-Omics [0.03%]
Correction: 酷拟态：利用单细胞和空间多组学重构MPN进化
Muhammad Shahid Iqbal,Abdullah K Alahmari,Mohd Faiyaz Khan et al.
Muhammad Shahid Iqbal et al.
Published Erratum
Clinical and experimental medicine. 2026 Jul 27;26(1):280. DOI:10.1007/s10238-026-02261-w 2026
Expression of VISTA on peripheral blood mononuclear cells in Systemic lupus erythematosus: association with disease activity and treatment status [0.03%]
系统性红斑狼疮外周血单个核细胞上VISTA的表达：与疾病活动度和治疗状态的关系研究
Afsaneh Enteshari-Moghaddam,Rozita Abolhasan,Meysam Motevasseli et al.
Afsaneh Enteshari-Moghaddam et al.
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease characterized by autoantibody production and multi-organ involvement due to dysregulated immune responses. Ongoing research aims to understand the underlying mechanism...
CK2 in triple-negative breast cancer: oncogenic signaling networks and emerging CK2 inhibitor-based combination therapies [0.03%]
CK2在三阴性乳腺癌中的致癌信号网络及基于CK2抑制剂的联合治疗新策略
Navas Shereef Ellyan,Angel Treasa Alex,Usha Yogendra Nayak et al.
Navas Shereef Ellyan et al.
The aggressive and highly heterogeneous subtype of breast cancer, triple-negative breast cancer (TNBC), has a poor response to conventional treatments and a high propensity for metastasis, causing unfavorable clinical outcomes. In TNBC, cas...
Machine learning-based identification of lactate metabolism-associated biomarkers in non-alcoholic fatty liver disease [0.03%]
基于机器学习的非酒精性脂肪肝疾病中乳酸代谢相关生物标志物识别
Xiaocui Wang,Xinhan Wang,Liang Zhao et al.
Xiaocui Wang et al.
To determine lactate metabolism-associated biomarkers for non-alcoholic fatty liver disease (NAFLD). Based on NAFLD datasets from the gene expression omnibus database and lactate metabolism-related genes from GeneCards database, NAFLD-lacta...
Von Willebrand, factor VIII, and D-dimer levels as predictors of risk and clinical outcomes in acute myeloid leukemia [0.03%]
血管性血友病因子、因子Ⅷ和D-二聚体在急性髓系白血病风险及临床结局中的预测价值
Hanaa Ali El-Sayed,Doaa H Sakr,Mohamed Awad Ebrahim et al.
Hanaa Ali El-Sayed et al.
Coagulopathies, infection, and CNS infiltration are common complications during induction therapy of acute myeloid leukemia (AML). Early identification of adverse-risk patients may improve outcomes. This study evaluated the predictive value...
ncRNA-driven regulation of PD-L1 in breast cancer: mechanisms of immune escape and therapeutic opportunities [0.03%]
乳腺癌中的ncRNA介导的PD-L1调控：免疫逃逸机制与治疗机会
Amirhossein Mardi,Sajjad Rajabi Moghaddam,Ali Roohi Motlagh et al.
Amirhossein Mardi et al.
Programmed death-ligand 1 (PD-L1) is an immune checkpoint molecule important in tumor immune evasion acting primarily by inhibiting T cell activation. In breast cancer, PD-L1 is frequently abnormally expressed and associated with tumor prog...
Neuropeptide Y promotes myocardial fibrosis post myocardial infarction reperfusion through Neuropeptide Y receptor type 1 [0.03%]
神经肽Y通过神经肽Y受体促进心肌梗死后再灌注损伤的纤维化形成
Dinghui Wang,Bo Wei,Chunfeng Cao et al.
Dinghui Wang et al.
Although the treatment of ischemic heart disease is becoming increasingly mature, the role of neuropeptide Y (NPY) in the pathophysiology after reperfusion still remains remains unanswered. In our study, we used a mouse model of myocardial ...
Circulating microRNAs as prognostic biomarkers in patients with oropharyngeal cancer undergoing radiotherapy: temporal dynamics analysis [0.03%]
放射治疗的口腔癌患者循环miRNA预后标志物的动态分析研究
Bartłomiej Tomasik,Damian Mikulski,Bartosz Kamil Sobocki et al.
Bartłomiej Tomasik et al.
The incidence of oropharyngeal cancer (OPC) is increasing. Thus, there is a need for biomarkers that can identify high-risk patients and support personalised treatment. This study investigated the prognostic significance of circulating micr...