Coexistence of two missense mutations in the KRAS gene in adenocarcinoma of the lung: a possible indicator of poor prognosis [0.03%]
肺腺癌中KRAS基因两个错义突变的共存可能是预后不良的一个标志
Manuela Spinelli,Persephone Du Parcq,Nandita Gupta et al.
Manuela Spinelli et al.
Background: KRAS mutations are present in up to 30% of patients with lung adenocarcinoma. The two most common KRAS mutations in non-small cell lung cancer (NSCLC) are G12C (~40%) and G12V (~22%). We describe the case of a...
Case Reports
Pathologica. 2022 Jun;114(3):221-227. DOI:10.32074/1591-951X-334 2022
Three cases of BRAF-mutant melanoma with divergent differentiation masquerading as sarcoma [0.03%]
3例分化方向不同且具有BRAF突变的黑色素瘤以肉瘤样形态表现病例报告
Michael A Cilento,Chankyung Kim,Sean Chang et al.
Michael A Cilento et al.
Melanoma is an important cause of skin cancer related death throughout the world, particularly in Europe, the United States, and Australia. Rarely melanoma undergoes divergent differentiation to simulate the full morphologic and immunohisto...
Case Reports
Pathologica. 2022 Jun;114(3):217-220. DOI:10.32074/1591-951X-771 2022
NTRK gene fusions in solid tumors: agnostic relevance, prevalence and diagnostic strategies [0.03%]
实体瘤中的NTRK基因重排：检测方法和临床意义
Antonio Marchetti,Benedetta Ferro,Maria Paola Pasciuto et al.
Antonio Marchetti et al.
A number of innovative drugs, developed for precision medicine, have shown impressive activity in neoplastic patients with rare molecular targets, independently from the site and type of tumor. This gave rise to the concept of agnostic trea...
Biomarker characterization in endometrial cancer in Italy: first survey data analysis [0.03%]
意大利子宫内膜癌生物标志物特征首次调查数据分析
Gian Franco Zannoni,Angela Santoro,Nicoletta D&#x;Alessandris et al.
Gian Franco Zannoni et al.
Objective: Endometrial carcinoma (EC) is the most common gynecological malignant disease in high income countries. The 2020 edition of the World Health Organization (WHO) Classification of Tumors of the Female Genital Tra...
From Pathognomicha and Passiologia to Pathologia: concise history of a neologism (1486-1598) [0.03%]
从特异性症状学和疾病情感学到病理学：一个新词的简史（1486-1598）
Diederik F Janssen
Diederik F Janssen
The etymology of the term pathology refers to one to the various ancient (Hippocratic, Galenic and Pseudo-Galenic) suggestions for subdividing the medical arts (medicinae artis partes), suggestions that came into print during the late fifte...
Subcutaneous dirofilariosis in Italy: a diagnostic hypothesis to remind when the anamnesis is misleading [0.03%]
意大利皮下旋毛虫病：误诊时的诊断假设需牢记
Naghia Ahmed,Leonardo Tonelli,Giuseppina Labagnara et al.
Naghia Ahmed et al.
Subcutaneous parasitic infections are possible matches in routine pathology and can be detected not only in patients coming from or travelling in tropical countries, but also when the anamnesis does not suggest at first worm infestations. ...
Case Reports
Pathologica. 2022 Apr;114(2):174-177. DOI:10.32074/1591-951X-297 2022
Alessandro Caputo,Maria Addesso,Filippo Fraggetta et al.
Alessandro Caputo et al.
The bladder is a rare site for breast cancer metastases, and only occasional reports are present in the literature. Most cases coexist with synchronous metastases elsewhere, but isolated cases of a single metastatic localization in the urin...
Metastasis of lung carcinoid in the thyroid gland after 18 years: it is never too late. A case report and review of the literature [0.03%]
肺类癌甲状腺转移18年后个例报告及文献回顾
Michele Dello Spedale Venti,Elisa Giannetta,Daniela Bosco et al.
Michele Dello Spedale Venti et al.
Metastasis to the thyroid gland is a rare event. To date, only 11 cases of metastasis from neuroendocrine tumors (NETs) originating in the lung have been reported. We present a case of a patient in his 40s harboring two nodules in the thyro...
A microcystic/reticular schwannoma in an unusual site: description of a retroperitoneal location and review of the literature [0.03%]
微囊型/网状施万瘤罕见部位的1例并文献复习
Rita Bianchi,Giulio Fraternali Orcioni,Bruno Spina et al.
Rita Bianchi et al.
Microcystic/reticular (MRV) schwannoma has been described since 2008, but remains a rarely encountered entity. MRV has a predilection for visceral locations and has variable histologic appareances. Given its rarity and anatomic variability,...
The "Queen of the Moors". Paleopathological investigation of a natural mummy from Scicli, South-Eastern Sicily [0.03%]
“摩尔人的女王”。对西西里东南部斯奇克利的一具天然木乃伊的病理学研究
Luca Ventura,Guido Romeo,Bettina Grimaldi et al.
Luca Ventura et al.
A natural, well-preserved mummy belonging to a 45-55 year old female was found in the Church of Santa Maria della Consolazione in Scicli, south-eastern Sicily. The body was submitted to external examination, digital radiology, and computed ...
Case Reports
Pathologica. 2022 Apr;114(2):152-158. DOI:10.32074/1591-951X-256 2022