Breast carcinoma metastasizing to an adrenocortical adenoma: a case of tumour-to-tumour metastasis [0.03%]
乳腺癌转移到肾上腺皮质腺瘤的一个病例：肿瘤转移到肿瘤病例
Maria Luísa Sacramento,João Menino,Vitor Proa et al.
Maria Luísa Sacramento et al.
Tumor-to-tumor metastasis (TTM) refers to a malignant tumor metastasizing to a second, distict tumor. It is a rare phenomenon and the most common donor organs are the lung and breast. Here in, we report a case of TTM metastasis of breast ca...
Case Reports
Pathologica. 2026 Apr;118(2):145-147. DOI:10.32074/1591-951X-2228 2026
Metastatic melanoma with heterologous bone after neoadjuvant immunotherapy: diagnostic insights [0.03%]
免疫治疗新辅助治疗后的黑色素瘤骨异位诊断思路
Ludovica Pepe,Vincenzo Fiorentino,Antonio Ieni et al.
Ludovica Pepe et al.
We report a BRAF V600E-mutated cutaneous melanoma (pT3b) with nodal metastases treated with neoadjuvant anti-PD-1 therapy. Axillary lymph node dissection demonstrated residual viable melanoma intimately associated with extensive heterologou...
Case Reports
Pathologica. 2026 Apr;118(2):142-144. DOI:10.32074/1591-951X-1977 2026
Lymphangitic breast cancer in explanted lungs with interstitial lung disease: an unexpected finding [0.03%]
伴有间质性肺疾病的移植肺中意外发现淋巴管侵犯的乳腺癌
Giuseppe Maggioni,Omar El Mnif,Eleonora Faccioli et al.
Giuseppe Maggioni et al.
A 60-year-old woman with end-stage fibrosing interstitial lung disease (ILD) underwent bilateral lung transplantation. Systematic histological analysis of the explanted lungs revealed extensive lymphangitic carcinomatosis and hilar lymph no...
Case Reports
Pathologica. 2026 Apr;118(2):138-141. DOI:10.32074/1591-951X-1823 2026
Histological insights into sudden, unexpected death due to tuberculosis: two autopsy case reports and review of the literature [0.03%]
结核病导致的突发意外死亡的病理学见解：两例尸检病例报告及文献回顾
Rosanna Zamparese,Margherita Neri,Giovanni Tossetta et al.
Rosanna Zamparese et al.
We report two singular cases of sudden death in which the cause was advanced tuberculosis infection. In the first case, a 24-year-old man died suddenly following massive hemoptysis due to erosion of the pulmonary vessels. The second case in...
Teaching with human remains: curatorship, technological innovation and ethical engagement at the Morgagni Museum of Human Anatomy [0.03%]
人体遗骸的教学：莫尔加尼解剖学博物馆的馆藏、技术创新和伦理互动
Giovanni Magno,Alberto Zanatta
Giovanni Magno
Medical museums are increasingly challenged to balance accessibility, educational effectiveness, and ethical responsibility, particularly when displaying human remains. Despite growing interest in digital museology, limited attention has be...
Technical feasibility of a long read, fourth generation sequencing platform in diagnostic profiling of clinical routine samples: a proof-of-concept study [0.03%]
基于长读取的第四代测序平台在临床常规样本诊断中的技术可行性研究：概念验证型研究
Domenico Vitale,Lorenzo Colarossi,Gianluca Russo et al.
Domenico Vitale et al.
Background: Next generation sequencing (NGS) impacted on clinical algorithm of solid tumor patients. A heterogeneous series of NGS platforms have been implemented in clinical practice but challenging handling procedures, ...
Nodular fibromuscular villous stromal dysplasia (NFMVSD): forensic insights into fetal/neonatal outcomes [0.03%]
结节性纤维肌绒毛状间质发育不良(NFMVSD)的法医病理学研究及其对胎儿/新生儿结局的影响
Ezio Fulcheri,Jennifer Belfiore,Carlo Bellini et al.
Ezio Fulcheri et al.
Objective: To assess the frequency, morphological features, and perinatal/forensic relevance of nodular fibromuscular villous stromal dysplasia (NFMVSD) in a large retrospective placental series. ...
Golden rules for optimizing the diagnostic pathway of IDH-mutant tumors: bridging evidence and clinical practice in cholangiocarcinoma and adult-type diffuse gliomas [0.03%]
IDH突变型肿瘤诊断路径优化的金标准：结合证据与临床实践以治疗胆管癌和成人弥漫性胶质瘤
Manila Antonelli,Valeria Barresi,Luca Bertero et al.
Manila Antonelli et al.
Background: Mutations in the isocitrate dehydrogenase (IDH) genes are key biomarkers in intrahepatic cholangiocarcinoma (CCA) and adult-type diffuse gliomas, although real-world adoption of comprehensive molecular diagnos...
AI for cervical cancer screening on whole slide images: opportunities with open-source simple tools [0.03%]
基于开源工具的宫颈癌全片数字切片筛查人工智能方法及应用机遇
Laura Nonnis,Lorenzo Putzu,Michela Vincis et al.
Laura Nonnis et al.
Objective: Cervical cancer remains a major global health burden, where early detection is critical. Cytological and histological assessments aim to identify precancerous squamous intraepithelial lesions (SILs). While arti...
Detection of NTRK gene fusions in sarcomas: a comparative study of Pan-TRK immunohistochemistry, FISH, and RNA-Based NGS [0.03%]
NTRK基因融合在肉瘤中的检测：Pan-TRK免疫组化、FISH和基于RNA的NGS比较研究
Stefania Cocchi,Marco Gambarotti,Gabriella Gamberi et al.
Stefania Cocchi et al.
Background: Fusion involving NTRK1, NTRK2 and NTRK3 are oncogenic driver occurring in several adult and pediatric tumor types. In sarcomas they are mostly found in infantile fibrosarcoma, inflammatory (IFS), inflammatory ...
Comparative Study
Pathologica. 2026 Apr;118(2):72-84. DOI:10.32074/1591-951X-1385 2026