Giulio Rossi,Anna Farnedi,Fabio Davoli et al.
Giulio Rossi et al.
The thoracic district is the most frequent visceral location of synovial sarcoma, generally involving lung and pleura as a large solid mass. We present herein a 57-year-old man with recurrent pneumothorax and a localized bulla at the lingul...
Case Reports
Pathologica. 2022 Aug;114(4):316-321. DOI:10.32074/1591-951X-377 2022
Pulmonary squamous cell carcinoma with a lepidic-pagetoid growth pattern [0.03%]
具有鳞状细胞癌-in-situ生长方式的肺鳞癌
Claudio Guerrieri,Mark Lindner,Joanna Sesti et al.
Claudio Guerrieri et al.
We report a rare case of a peripheral squamous cell carcinoma (SCC) of the lung in which most of the tumor displayed a "lepidic" growth pattern. The tumor cells also appeared to grow along the alveolar walls between the overlying pneumocyte...
Case Reports
Pathologica. 2022 Aug;114(4):304-311. DOI:10.32074/1591-951X-450 2022
Use of digital pathology and artificial intelligence for the diagnosis of Helicobacter pylori in gastric biopsies [0.03%]
数字病理学和人工智能在胃活检标本中幽门螺杆菌诊断中的应用
Daniel S Liscia,Mariangela D&#x;Andrea,Elena Biletta et al.
Daniel S Liscia et al.
Objective: A common source of concern about digital pathology (DP) is that limited resolution could be a reason for an increased risk of malpractice. A frequent question being raised about this technology is whether it ca...
In-house testing for homologous recombination repair deficiency (HRD) testing in ovarian carcinoma: a feasibility study comparing AmoyDx HRD Focus panel with Myriad myChoiceCDx assay [0.03%]
卵巢癌同源重组修复缺陷(HRD)的院内检测可行性研究：AmoyDx HRD Focus Panel与Myriad myChoice CDx Assay的对比分析
Caterina Fumagalli,Ilaria Betella,Alberto Ranghiero et al.
Caterina Fumagalli et al.
Background: Homologous recombination repair (HRR) is the main mechanism of repair of DNA double-strand breaks. Its deficiency (HRD) is a common feature of epithelial ovarian cancers (EOCs). BRCA1/2 mutations and/or other ...
Gianni Bussolati
Gianni Bussolati
Andrea Ascione,Guido Martignoni,Giulia d&#x;Amati et al.
Andrea Ascione et al.
A 79-year-old woman underwent surgical resection of a peripheral, solitary, pulmonary lesion that was diagnosed as malignant PEComa. Her clinical history was positive for uterine leiomyosarcoma, excised 20 years before. Re-evaluation of the...
Case Reports
Pathologica. 2022 Aug;114(4):312-315. DOI:10.32074/1591-951X-762 2022
Immunohistochemistry with 3 different clones in anaplastic lymphoma kinase fluorescence in situ hybridization positive non-small-cell lung cancer with thymidylate synthase expression analysis: a multicentre, retrospective, Italian study [0.03%]
意大利多中心回顾性研究：含三种不同克隆的间变性淋巴瘤激酶荧光原位杂交阳性非小细胞肺癌的免疫组化与胸苷酸合成酶表达分析
Paolo Bironzo,Laura Melocchi,Valentina Monica et al.
Paolo Bironzo et al.
Introduction: ALK rearrangement is the only druggable oncogenic driver detectable by immunohistochemistry (IHC) not requiring further confirmation of positivity in accessing first-line specific inhibitors. ALK-positive pa...
Multicenter Study
Pathologica. 2022 Aug;114(4):278-287. DOI:10.32074/1591-951X-756 2022
Carlo Alfredo Clerici,Carlo Patriarca
Carlo Alfredo Clerici
Alongside his anatomical studies, which laid the foundations of modern neuroanatomy, Santiago Ramón y Cajal also showed a lively interest in studying dreams, hypnosis, and the world of the paranormal. On his travels to worlds far removed f...
Considerations about the burial of foetuses of less than 20-weeks gestational age [0.03%]
论小于孕龄20周胎龄胎儿埋葬的若干思考
Ezio Fulcheri,Francesca Buffelli,Cristina Fiore et al.
Ezio Fulcheri et al.
Primary extraskeletal myxoid chondrosarcoma of the breast: report of a case and literature review [0.03%]
原发于乳腺的Extraskeletal肌样软骨肉瘤1例报告及文献复习
Shivani Sharma,Anandi Lobo,Anurag Sharma et al.
Shivani Sharma et al.
Primary extraskeletal myxoid chondrosarcoma (pEMC) of the breast is rare and only a few cases have been reported to date. Herein, we report a case of primary EMC of the breast in a 45-year-old female. The patient presented with a left breas...