Gut microbiome profiles as predictors of response to chemoradiotherapy in locally advanced rectal cancer [0.03%]
局部晚期直肠癌患者肠道微生物组谱型可预测化学放射治疗反应
Jiya You,Rashid Mahmood Khan,Nidhi Reji
Jiya You
This prospective cohort study investigates the predictive role of gut microbiota composition in determining the therapeutic response to neoadjuvant chemoradiotherapy (CRT) in patients with locally advanced rectal cancer (LARC) at Qiqihar Ji...
Genome-resolved analysis of multidrug-resistant ESKAPE pathogens reveals Klebsiella pneumoniae diversity and plasmid-mediated resistance in a patient in intensive care [0.03%]
基因组解析分析了ESKAPE病原体的多重耐药性，发现在重症监护患者中的肺炎克雷伯氏菌多样性以及质粒介导抗性
Aarti Pustam,Rajeev P Nagassar,Jayaraj Jayaraman et al.
Aarti Pustam et al.
Multidrug-resistant (MDR) Gram-negative pathogens continue to threaten patient outcomes in intensive care units (ICUs) worldwide, particularly in regions where genomic surveillance is limited. Understanding intra-host genomic diversity and ...
Longitudinal effects of antiretroviral therapy on the oral microbiota in people living with HIV: A systematic review [0.03%]
抗逆转录病毒治疗对HIV携带者口腔微生物群纵向影响的系统评价研究
Handayani Ali,Irene Edith Rieuwpassa,Nurlindah Hamrun et al.
Handayani Ali et al.
People living with HIV frequently experience oral microbial dysbiosis, contributing to oral disease burden and reduced quality of life. Although antiretroviral therapy (ART) effectively suppresses viral replication and promotes immune recov...
Rare case of bacteremia, liver abscess and possible infective endocarditis caused by Fusobacterium nucleatum [0.03%]
由核梭杆菌引起的罕见菌血症、肝脓肿和可能感染性心内膜炎病例
Despoina Spentzouri,Petros Ioannou,Andria Papazachariou et al.
Despoina Spentzouri et al.
Fusobacterium nucleatum is a Gram-negative obligate anaerobic bacterium typically found as a commensal in the human oral cavity, gastrointestinal and female genital tract. While it is a common cause of endodontic infections, it is a rare ca...
New insights into Salmonella virulence: Detection of spvB and spvR genes in avian and human isolates from northeastern Algeria [0.03%]
鼠伤寒沙门氏菌毒力因子spvR和spvB基因的广泛检测及其在进化上的意义
Amira Kout,Radia Boufermes,Rania Laouar et al.
Amira Kout et al.
The emergence of highly virulent and multidrug-resistant Salmonella strains continues to pose a major global public health concern. Building on our previous investigation of 80 Salmonella isolates obtained from avian and human sources in no...
Integrative analysis of the gut-liver-heart axis in coronary artery disease: From chronic metabolic dysbiosis to acute cardiogenic shock [0.03%]
冠心病肠道-肝脏-心脏轴的整体分析研究：从慢性代谢性菌群失调到急性心源性休克
Muhammad Salman Khan,Muhammad Naveed Khan,Syed Muhammad Umair et al.
Muhammad Salman Khan et al.
The complex interplay between chronic metabolic disorders and acute cardiovascular decompensation represents a critical frontier in cardiology. This integrative research program conducted at Chongqing Medical University systematically exami...
Molecular epidemiology and prognostic impact of lower respiratory tract infections during immune checkpoint inhibitor therapy in advanced non-small cell lung cancer: A retrospective cohort study [0.03%]
免疫检查点抑制剂治疗过程中晚期非小细胞肺癌下呼吸道感染的分子流行病学及预后影响：一项回顾性队列研究
Ning Xu,Chao Li
Ning Xu
Patients with advanced non-small cell lung cancer (NSCLC) are prone to lower respiratory tract infection (LRTI) during immune checkpoint inhibitor (ICI) treatment, but the pathogen spectrum and clinical impact remain unclear. This study pro...
Exploring the gut-lung axis in post-liver transplant acute lung injury: A multi-omics approach [0.03%]
肝移植后急性肺损伤的肠肺轴多组学研究
Abdul Ahad Mehboob,Remsha Fatima,Saadia Kanwal et al.
Abdul Ahad Mehboob et al.
Acute lung injury (ALI) is a significant post-operative complication of liver transplant (LT), with mounting evidence suggesting a role for the gut-lung axis. However, the mechanistic link between gut microbiota dysbiosis and ALI pathogenes...
Comprehensive whole-genome sequencing reveals the resistome, virulome, and mobile genetic architecture of multidrug-resistant Acinetobacter baumannii [0.03%]
全基因组测序揭示多重耐药鲍曼不动杆菌的耐药谱、毒力谱和可移动遗传元件架构
Kannika Parameshwari Kannan,A S Smiline Girija
Kannika Parameshwari Kannan
Acinetobacter baumannii is a major cause of hospital-acquired infections and has emerged as a critical multidrug-resistant (MDR) pathogen with limited therapeutic options. In this study, two MDR clinical isolates from a tertiary care hospit...
Kimaya Kaushik,Mihir Sharma,Ritik Sharma et al.
Kimaya Kaushik et al.
Aging is the natural process of changes that are accumulated over time and are responsible for the ever-increasing susceptibility to diseases and death. Extensive research has been done to understand the role of gut microbiota in aging, how...