DMRTA2 Regulates Radial Glial Maintenance and Tumorigenicity of Paediatric High-Grade Glioma [0.03%]
Hitomi N Royston,Autumn B Hampton,Elissa G Oliver et al.
Hitomi N Royston et al.
DMRTA2 is a member of the evolutionarily conserved transcription factor family involved in various developmental processes including neurogenesis. However, the roles of DMRTA2 in human development and disease are not fully characterised. Si...
Nonlinear Bivariate Associations and Mononuclear Cell-Type-Specific Expression Level Differences in the STING Signalling Pathway [0.03%]
David Kaplan,Eric L Christian
David Kaplan
Understanding intracellular signalling pathways is crucial since they regulate essential functional activities. Bivariate relationships have been useful in delineating these pathways in clinical samples. In our previous studies, we have fou...
Increased CD44 Expression in Endothelial Cells Induced by Advanced Glycation End Products Leads to Insufficient Maturation of Angiogenesis [0.03%]
Xiaoxia Huang,Zhuanhua Liu,Jiaqing Hu et al.
Xiaoxia Huang et al.
Pathological angiogenesis occurs in various diseases, including tumours, diabetes and wound healing. The endothelial cells lining these aberrant neovessels exhibit abnormal morphology, with loosely attached or absent pericytes and the basem...
The SGLT2 Inhibitor Canagliflozin Promotes β-Cell Regeneration and Restores and Stabilises β-Cell Identity in a Polygenic Model of Severe Early-Onset Type 2 Diabetes [0.03%]
SGLT2抑制剂卡格列净可促进β细胞再生并在严重早期发病的2型糖尿病多基因模型中恢复和稳定β细胞身份
Iuliana Popescu,Robert C Bunn,Phil Ray et al.
Iuliana Popescu et al.
Childhood obesity has led to an increase in type 2 diabetes (T2D) among youth, with adolescent-onset T2D showing a rapid decline in β-cell function compared to adult-onset cases. While the disease progression is more aggressive in early li...
A Brain-Targeting Curcumin Analog Inhibits Glioblastoma Progression Through THBS1/TGF-β1/PI3K-AKT Axis Modulation: Evidence From Experimental and Bioinformatic Analyses [0.03%]
一种靶向大脑的姜黄素类似物通过调节THBS1/TGF-β1/PI3K-AKT轴抑制胶质母细胞瘤的发展：实验和生物信息学证据
Zijian Han,Xuetao Li,Yang Zhu et al.
Zijian Han et al.
Glioblastoma (GBM) is the most aggressive primary brain tumour, associated with a dismal prognosis and an urgent need for innovative therapeutic strategies. To address this challenge, our group developed DMC-GF, a novel brain-targeted curcu...
Correction to "Protectin DX Promotes Epithelial Injury Repair and Inhibits Fibroproliferation Partly via ALX/PI3K Signalling Pathway" [0.03%]
"DHX保护修复上皮损伤和抑制纤维增生的部分机制是通过ALX/PI3K信号通路实现的——对“DHX促进上皮损伤修复和抑制纤维化是部分通过ALX/PI3K信号通路实现的”的更正
Published Erratum
Journal of cellular and molecular medicine. 2026 Mar;30(5):e71087. DOI:10.1111/jcmm.71087 2026
ODC1 Polyamine Metabolism Drives Prostate Cancer via AKT and Splicing [0.03%]
ODC1多胺代谢通过AKT和剪接驱动前列腺癌的发展
Jian Ma,Ting Pan,Shengli Sun et al.
Jian Ma et al.
Prostate cancer is an aggressive disease with limited quantifiable biomarkers. One gene of interest is ODC1, which encodes ornithine decarboxylase, the rate-limiting enzyme converting ornithine to putrescine in polyamine metabolism. Althoug...
Jianpi Jiedu Xiaozheng Fang Regulates Hepatocellular Carcinoma Proliferation and Metastasis Based on Network Pharmacology [0.03%]
健脾解毒消证方通过网络药理学调控肝癌增殖转移作用机制研究
Bin Li,Han-Qian Shi,Rui Luo et al.
Bin Li et al.
Hepatocellular carcinoma (HCC) is a primary malignant tumour that impacts patients' quality of life. Currently, clinical experience from The First Affiliated Hospital of Guangzhou University of Chinese Medicine suggests that Jianpi Jiedu Xi...