Isolation of bacteria from remote high altitude Andean lakes able to grow in the presence of antibiotics [0.03%]
从安第斯山脉偏远的高原湖泊中分离出能在抗生素存在下生长的细菌
Julián R Dib,Annika Weiss,Anna Neumann et al.
Julián R Dib et al.
High altitude Andean lakes are placed in Puna desert over 4400 above sea level. Completely isolated, they are exposed to extreme environmental factors like high levels of salinity, UV radiation and heavy metals and low concentrations of pho...
Dietrich Hasper,Joerg C Schefold,Daniel C Baumgart
Dietrich Hasper
Abdominal infections are associated with significant morbidity and mortality. Nearly all bacteria causing abdominal infections are derived from the endogenous flora of the alimentary tract. The resulting infection is typically polymicrobial...
Triggering Receptor Expressed on Myeloid Cells (TREM) family and the application of its antagonists [0.03%]
表达于髓系细胞的触发受体(TREMs)家族及其拮抗剂的应用进展
Eleanor J Molloy
Eleanor J Molloy
The Triggering Receptors Expressed on Myeloid cells (TREM) are a family of activating receptors with some homology with activating natural killer cell receptors. TREM-1 is an activating receptor on neutrophils and monocytes that plays an im...
Barbara Zechini,Ilaria Versace
Barbara Zechini
Resistance of bacteria to many classes of antibiotics is an increasing problem worldwide. Multidrug resistance efflux pumps are recognized as an important component of resistance in both Gram-positive and Gram-negative bacteria. Some bacter...
Antonio Giorgio,Antonella Di Sarno,Giorgio de Stefano et al.
Antonio Giorgio et al.
Percutaneous treatment of Hydatid Liver Cyst (HLC) with scolicidal agent under ultrasound guidance is now worldwide used after the advent of Percutaneous-Aspiration-Injection and Re-Aspiration (PAIR) and its modifications. Although HLC repr...
Jason J Schafer,Debra A Goff,Julie E Mangino
Jason J Schafer
Doripenem (DPM) is the newest antimicrobial in the carbapenem class. It is a broad spectrum agent with activity against gram-positive, gram-negative and anaerobic bacteria. in vitro Susceptibility testing has demonstrated potent activity fo...
Jennifer C Pai,Jamie N Sutherland,Jennifer A Maynard
Jennifer C Pai
The global market for monoclonal antibody therapeutics reached a total of $11.2 billion in 2004, with an impressive 42% growth rate over the previous five years and is expected to reach approximately $34 billion by 2010. Coupled with this g...
Paolo R Errante,Josias B Frazão,Antonio Condino-Neto
Paolo R Errante
Chronic granulomatous disease (CGD) is a primary immunodeficiency characterized by early onset of recurrent and severe infections. The molecular defects causing CGD are heterogeneous and lead to absence, low expression, or malfunctioning of...
Chand Wattal,Jaswinder K Oberoi,Reena Raveendran et al.
Chand Wattal et al.
In the era of multidrug resistance keen interest needs to be taken in developing newer antiinfective drugs and patents. We all are aware that not many such drugs are readily available and still less are in the pipeline, and thus, such paten...
Sourav Sen,Adesh G Mathur,Rajiv M Gupta et al.
Sourav Sen et al.
HIV disease is a chronic infection that requires lifelong treatment with the aim of suppressing the circulating viral load in order to improve the host immune status. The development of safe and effective antiretroviral agents with unique r...