Novel Oral Anticoagulants for Venous Thromboembolism with Special Emphasis on Risk of Hemorrhagic Complications and Reversal Agents [0.03%]
新型口服抗凝药物治疗静脉血栓栓塞症及其出血并发症的风险和逆转剂的特异性强调
Zaheer Ahmed,Seemeen Hassan,Gary A Salzman
Zaheer Ahmed
Warfarin was the only oral anticoagulant available for the treatment of venous thromboembolism for about half a century until the recent approval of novel oral agents dabigatran, rivoraxaban and apixaban. This presents new classes of medica...
Enhancing Immunogenicity of Cancer Vaccines: QS-21 as an Immune Adjuvant [0.03%]
用于癌症疫苗的QS-21免疫佐剂增强其免疫原性研究
David Y Gin,Susan F Slovin
David Y Gin
Saponins comprise a class of plant natural products that incorporate a lipophilic terpenoid core, to which is appended one or more carbohydrate residues. They are amphiphilic molecules and often exhibit toxic biological profiles, likely as ...
Vladimir Skljarevski,Shuyu Zhang,Smriti Iyengar et al.
Vladimir Skljarevski et al.
The primary objective of this study is to review the efficacy of duloxetine in treating chronic pain using the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) recommendations for clinical significance ac...
Who's Winning the War? Molecular Mechanisms of Antibiotic Resistance in Helicobacter pylori [0.03%]
战争谁胜谁负？幽门螺杆菌抗生素抗性的分子机制
Kathleen R Jones,Jeong-Heon Cha,D Scott Merrell
Kathleen R Jones
The ability of clinicians to wage an effective war against many bacterial infections is increasingly being hampered by skyrocketing rates of antibiotic resistance. Indeed, antibiotic resistance is a significant problem for treatment of dise...
Anurag Sharma,Manish Tandon,Dinesh S Bangari et al.
Anurag Sharma et al.
Definitive treatment of cancer has eluded scientists for decades. Current therapeutic modalities like surgery, chemotherapy, radiotherapy and receptor-targeted antibodies have varied degree of success and generally have moderate to severe s...