Expression dynamics of mCry3A and eCry3.1Ab transgenes in Bt corn hybrids across growth and environments [0.03%]
抗虫玉米杂交种中mCry3A和eCry3.1Ab转基因表达量的时空动态及环境效应研究
Isaac Oyediran,Jared Conville,Eric Boudreau
Isaac Oyediran
In 2017 and 2018, studies were conducted in Iowa, US across three environments with a history of greater than expected corn rootworm injury i.e., greater than one node of injury to (US EPA 2009) and one environment without rootworm injury, ...
Exploratory conversations with biodiversity-oriented civil society groups on the potential applications of gene drive-modified mosquitoes for malaria control in Tanzania [0.03%]
坦桑尼亚生物多样性民间社会组织关于疟疾控制的基因驱动改造蚊子潜在应用的探索性对话
Marceline F Finda,Maganga Sambo,Goodluck Malika et al.
Marceline F Finda et al.
Gene drive-modified mosquitoes (GDMMs) are gaining attention as sustainable tools to complement existing malaria control strategies. Their ability to self-propagate and spread through wild mosquito populations offers the promise of low-cost...
The Agrobacterium-mediated genetic transformation: a gateway for efficient CRISPR/Cas9 gene editing in leguminous [0.03%]
农杆菌介导的遗传转化：豆科植物CRISPR/Cas9基因编辑的有效途径
Imane Sarroukh,Mohammed Ibriz,Lamia Yakkou et al.
Imane Sarroukh et al.
Climate change enhances the damaging consequences of abiotic and biotic stressors, leading to severe soil fertility loss and ecosystem degradation worldwide. Leguminous have contributed significantly to replenishing soil nitrogen via symbio...
A CRISPR/Cas9 assisted strategy for the conditional expression of human NF-kappaB c-Rel cDNA in mouse T cells: design, prospects, and challenges [0.03%]
基于CRISPR/Cas9的条件表达人NF-κB c-Rel cDNA的策略：设计、前景与挑战
Corynn N Appolonia,Joshua T Centore,Sadhanshu Shukla et al.
Corynn N Appolonia et al.
Nuclear factor-κB protein c-Rel is a critical regulator of autoimmune diabetes. We found that c-Rel O-GlcNAcylation at serine-350 increases with hyperglycemia, which results in increased transcription of proautoimmune Th1 cytokines, interl...
Reaumuria trigyna transcription factor RtWRKY49 confers cold tolerance to Arabidopsis thaliana [0.03%]
雷姆里乌穆利亚三花序功能基因RtWRKY49可增强拟南芥耐冷性
Chao Du,Ziqi Gao
Chao Du
Cold stress can greatly narrow the development and living spaces of plants. As one endangered xerophytic shrub, Reaumuria trigyna can adapt the harsh cold, but the underlying molecular mechanisms remain unknown. Here, the RtWRKY49 gene of R...
Tissue culture optimization and genome editing for yield improvement of an Indian rice landrace Chittimuthyalu [0.03%]
提高印度稻地方品种Chittimuthyalu产量的组织培养优化和基因组编辑
Faisal Yousuf,Manish Solanki,Surya Satyanarayana Singh et al.
Faisal Yousuf et al.
Chittimuthyalu, a rice landrace from Southern India, is known for its pleasant aroma, rich nutritive value, and excellent cooking qualities. However, it has a poor plant type (tall and weak stem prone to lodging) and is low yielding. The ef...
Functional divergence of zebrafish keap1 paralogs revealed by CRISPR/Cas9-mediated gene editing: a specialized role for keap1b in inflammation [0.03%]
利用CRISPR/Cas9基因编辑揭示斑马鱼keap1冗余基因的功能分化：KEAP1B在炎症反应中具有特殊功能
Vu Thanh Nguyen,Bui Thi Thu Van,Tran Ngoc Uyen et al.
Vu Thanh Nguyen et al.
The Keap1/Nrf2 signaling pathway is a master regulator of cellular defense against oxidative and electrophilic stress. In teleosts like zebrafish (Danio rerio), whole-genome duplication resulted in two keap1 paralogs, keap1a and keap1b, who...
Deciphering the cucumber ATG6 and its promoter to enhance abiotic stress tolerance and drive stress-responsive transgene expression in plants [0.03%]
黄瓜ATG6及其启动子的解析及在提高植物逆境抗性和驱动胁迫响应的目的基因表达中的应用研究
Issariya Dachphun,Phasanat Supphokha,Supachai Vuttipongchaikij et al.
Issariya Dachphun et al.
Developing climate-resilient plants with enhanced tolerance to abiotic stresses such as drought and salinity is essential for mitigating the impact of climate change on agriculture. One promising approach is the heterologous expression of s...
Avenues of genome editing for color trait improvement in ornamental fishes: current status and future perspectives [0.03%]
观赏鱼类色彩性状改良的基因组编辑途径：现状与未来展望
S S Priyanka,Gowhar Iqbal,N C Nidarshan et al.
S S Priyanka et al.
Ornamental fish industries are growing sectors contributing significantly to livelihood, trade and export, driven by the worldwide demand for colourful and unique species. Pigmentation is the focal point of the visual appeal of ornamental f...
A novel tamoxifen-inducible Mct8-CreERT2 mouse model for targeted studies of Mct8-expressing cells and thyroid hormone transport and function [0.03%]
一项新颖的他莫昔芬诱导型Mct8-CreERT2小鼠模型用于靶向研究表达Mct8的细胞和甲状腺激素转运及功能
Anna Molenaar,Noémi Mallet,Marin Bralo et al.
Anna Molenaar et al.
Deficiency of the Monocarboxylate Transporter 8 (MCT8) severely impairs thyroid hormone (TH) transport into the brain, disrupting brain development as well as peripheral TH homeostasis. Studies assessing MCT8 expression patterns and tissue-...