'Whole-Body Pharmacokinetics of Lipid, mRNA and Translated Protein Following Intravenous Administration of Spike Protein Expressing mRNA-LNP in Mice' [0.03%]
intravenous注射 Spike蛋白表达mRNA-lipid nanoparticle的小鼠全身药代动力学：脂质、信使rna和翻译蛋白质
Mokshada Kumar,Shrusti Tiwari,Aneesh Rajwade et al.
Mokshada Kumar et al.
Aim: Lipid nanoparticle (LNP)-encapsulated mRNAs (mRNA-LNPs) are being explored for various prophylactic and therapeutic applications. However, the relationship between the pharmacokinetics (PK) of lipid, mRNA, and expres...
Factors Associated with Parental Vaccine Hesitancy in Childhood Immunization: Insights from a Cross-Sectional Survey in Southern Italy [0.03%]
意大利南部儿童免疫规划中父母接种犹豫的相关因素：横断面调查分析
Maria Antonietta Barbieri,Giuseppe Cicala,Antonino Molonia et al.
Maria Antonietta Barbieri et al.
Introduction: Parental vaccine hesitancy (VH) threatens childhood immunization and may improve vaccination coverage. This study aimed to investigate parental VH factors in childhood immunization in Southern Italy, focusin...
New Vistas for Withania somnifera in Signal Transduction of Inflammation and Aging [0.03%]
Withania somnifera在炎症和衰老信号转导中的新展望
Eshita Sharma,Dilip Mehta,Prem Muthuraj et al.
Eshita Sharma et al.
Aging in humans is a multidimensional complexity featured by systematic chronic inflammation and further accompanied by organ dysfunction, gut dysbiosis, immune senescence, and age-related diseases. Chronic inflammation in cells relates to ...
Melt-Extruded Paclitaxel Nanocrystal-Loaded Sutures for Sustained Local Drug Delivery [0.03%]
用于持续局部给药的载熔融挤出紫杉醇纳米晶体缝线
Hala M Abdelhakk,Alhassan Issa,Crystal S Shin et al.
Hala M Abdelhakk et al.
Purpose: To develop biodegradable poly(lactic‑co‑glycolic acid) (PLGA) sutures loaded with paclitaxel (PTX) nanocrystals for sustained local drug delivery and to systematically evaluate their physicochemical, mechanical...
Henrietta Tsosie,James Thomas,John Strong et al.
Henrietta Tsosie et al.
Purpose: This study examined how controlled punch surface preparation and subsequent atmospheric aging influence adhesion between punch metal and formulation powder during tablet compaction. We aimed to clarify how the ev...
Correction: A Multi-Functional Tumor Theranostic Nanoplatform for MRI Guided Photothermal-Chemotherapy [0.03%]
题目校正：一种多模式肿瘤诊疗纳米平台用于MRI引导的光热化疗
Jinjin Shi,Binghua Wang,Zhaoyang Chen et al.
Jinjin Shi et al.
Published Erratum
Pharmaceutical research. 2026 Mar 26. DOI:10.1007/s11095-026-04071-x 2026
A Comprehensive Review of the Revolutionary Potential of Blockchain in Safe, Secure, and Sustainable Pharmaceutical Operations [0.03%]
区块链在安全、可靠和可持续的医药运营中的革命潜力全面回顾
Md Faiyazuddin,Keshav Moharir,Amol D Gholap et al.
Md Faiyazuddin et al.
Background: Pharmaceutical research and industrial operations generate vast volumes of sensitive data across drug discovery, formulation development, manufacturing, and distribution, necessitating secure, transparent, and...
Formation Mechanism of N-Despropyl Ropinirole in Ropinirole Hydrochloride Extended-Release Tablets: Nucleophilic Oxidation or Free Radical-Mediated Oxidation? [0.03%]
盐酸罗吡尼咯缓释片中N-脱丙基降解产物的生成机制：亲核氧化还是自由基介导的氧化？
Kong Wu,Jinsheng Lin,Xiao Liang et al.
Kong Wu et al.
Purpose: To probe the formation mechanism of N-despropyl ropinirole, an oxidative degradant in ropinirole hydrochloride extended-release tablets. Methods:...
Hospital-Compounded Birabresib Capsules for NUT Carcinoma: A Quality- and Risk-Based CMC Strategy [0.03%]
NUT癌医院内调配的倍拉溴吸入用 капсул：基于质量和风险的CMC策略
Maxime Annereau,François-Xavier Legrand,Maria Virginia Sánchez-Becerra et al.
Maxime Annereau et al.
Purpose: NUT carcinoma is an ultra-rare and highly aggressive malignancy lacking authorised systemic therapies. Birabresib, a bromodomain and extra-terminal (BET) inhibitor, has shown preliminary clinical activity; howeve...
Investigation into Clearance of Organic Compounds from Biomanufacturing Process Streams during Ultrafiltration/Diafiltration [0.03%]
超滤/透析过程中有机化合物的清除研究——生物制造过程流中的有机化合物清除研究
Noemí Dorival-García,Anna Mulligan,Ronan Hayes et al.
Noemí Dorival-García et al.
Objective: Ultrafiltration and diafiltration (UF/DF) operations have been demonstrated to clear leachables from drug substance, however there is limited data available. Consequently, comprehensive and systematic character...