Correction: Development of Alcohol-Resistant Extended-Release Formulations: Regulatory Considerations and Formulation Strategies [0.03%]
Correction: Development of Alcohol-Resistant Extended-Release Formulations: Regulatory Considerations and Formulation Strategies——酒精耐受型缓释制剂的开发：监管因素及处方策略纠正论文
Ming Ji,Nitin K Swarnakar,Shanmuka Harish Chalamuri et al.
Ming Ji et al.
Published Erratum
Pharmaceutical research. 2026 Mar 23. DOI:10.1007/s11095-026-04057-9 2026
Mechanistic Insights into pH-Responsive Drug Release and Antitumor Effects of an Albumin-Pirarubicin Conjugate [0.03%]
白蛋白-吡喃阿霉素结合物的pH响应性药物释放及抗肿瘤效应机制研究
Kenji Tsukigawa,Shuhei Imoto,Kotone Imamura et al.
Kenji Tsukigawa et al.
Purpose: This study provides mechanistic insight into the behavior of HSA-THP, a human serum albumin-pirarubicin conjugate linked via a pH-sensitive hydrazone bond. Building upon our previous synthesis, we aimed to elucid...
Development of a Dual-Isotope Imaging Technique for Simultaneous Quantification and Evaluation of Biodistribution of Antibodies Using "XCam-CdTe" [0.03%]
开发一种使用“XCAM-CdTe”对抗体进行同时定量和评估分布的双同位素成像技术
Miho Nagayasu,Miho Katsuragawa,Kazuhisa Ozeki et al.
Miho Nagayasu et al.
Purpose: The tissue distribution of 125I- and 111In-labeled antibodies in a single animal remains challenging to assess simultaneously and sequentially using conventional methods. This study developed a method using "XCam...
Cindy Chung,Erica Schlesinger
Cindy Chung
Binding Kinetics Can Explain Linear and Nonlinear Pharmacokinetics of Dipeptidyl Peptidase-IV Inhibitors Within a Single Target-Mediated Framework [0.03%]
结合动力学可以解释二肽基肽酶-IV抑制剂的线性和非线性药代动力学在一个单一的目标介导框架内
Adam Elalem,Mfonabasi E Ette,Donald E Mager
Adam Elalem
Introduction: Dipeptidyl peptidase-IV inhibitors (DPP4i) are a class of small-molecule drugs for the treatment of patients with type 2 diabetes mellitus. Despite their common mechanism of action, the pharmacokinetics (PK)...
Evaluation of Mass Spectrometry Compatible Reagents for Determining Small Molecule Loading in Poly(lactic acid) Nanoparticles [0.03%]
用于测定聚乳酸纳米颗粒中微量小分子负载的与质谱兼容的试剂的评价
Samuel A Krug,Andrea L Cottingham,Masahiro Iwamoto et al.
Samuel A Krug et al.
Objective: The objective was to understand if sufficient base hydrolysis and subsequent small molecule quantitation within poly(lactic acid) nanoparticles (PLA-NPs) could be achieved using a mass spectrometry friendly vol...
Regional Nasal Drug Deposition in Pediatric vs. Adult Models: In vitro Insights into User Technique and Breathing Patterns Sensitivity [0.03%]
儿科与成人模型的区域性鼻内给药沉积情况：用户操作技术及呼吸模式敏感性的体外研究见解
Mohammad Hejazi,Xiomara Owen,David J Edwards et al.
Mohammad Hejazi et al.
Purpose: Although in vitro studies recommended for establishing bioequivalence of locally acting nasal suspension products provide useful information regarding product performance, currently they are not designed to fully...
Hannah R Weiler,Lauren M Le,Hala M Fadda
Hannah R Weiler
Purpose: Pediatric global regulatory initiatives have come into place to address gaps in evidence-based medicine for children. Objective of this study was to assess age-appropriateness of oral pediatric formulations autho...
Impact of Postnatal Changes in Creatinine Levels on Plasma Gentamicin Concentrations in Neonates [0.03%]
新生儿肌酐水平产后变化对血浆庆大霉素浓度的影响
Haruka Tsushita,Ryota Tanaka,Masanori Inoue et al.
Haruka Tsushita et al.
Objective: Gentamicin (GM), a renally eliminated drug, is widely used to treat infections in neonates. Neonatal dosing is typically based on body weight and postmenstrual age (PMA). Although serum creatinine (Cr) is the g...
Advancing Sterilization of Medical Implant Polymers: Novel Low-Temperature Deep-vacuum Vaporized H2O2 Technology Surpasses Current Methods [0.03%]
医疗器械植入用高分子材料的新型低温真空等离子灭菌技术及应用研究进展
Abinaya Nallathambi,Enrica Chiesa,Mariella Rosalia et al.
Abinaya Nallathambi et al.
Purpose: To develop a deep vacuum vaporized hydrogen peroxide (VH₂O₂) sterilization method capable of preserving the structural and functional integrity of biocompatible polymeric electrospun mats usable as advanced bio...